An overview of the serpin superfamily RHP Law, Q Zhang, S McGowan, AM Buckle, GA Silverman, W Wong, ... Genome biology 7, 1-11, 2006 | 907 | 2006 |
The structural basis for membrane binding and pore formation by lymphocyte perforin RHP Law, N Lukoyanova, I Voskoboinik, TT Caradoc-Davies, K Baran, ... Nature 468 (7322), 447-451, 2010 | 491 | 2010 |
The MACPF/CDC family of pore‐forming toxins CJ Rosado, S Kondos, TE Bull, MJ Kuiper, RHP Law, AM Buckle, ... Cellular microbiology 10 (9), 1765-1774, 2008 | 350 | 2008 |
Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack JA Lopez, O Susanto, MR Jenkins, N Lukoyanova, VR Sutton, RHP Law, ... Blood, The Journal of the American Society of Hematology 121 (14), 2659-2668, 2013 | 342 | 2013 |
A common fold mediates vertebrate defense and bacterial attack CJ Rosado, AM Buckle, RHP Law, RE Butcher, WT Kan, CH Bird, K Ung, ... Science 317 (5844), 1548-1551, 2007 | 330 | 2007 |
GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop G Fenalti, RHP Law, AM Buckle, C Langendorf, K Tuck, CJ Rosado, ... Nature structural & molecular biology 14 (4), 280-286, 2007 | 267 | 2007 |
The X-ray crystal structure of full-length human plasminogen RHP Law, T Caradoc-Davies, N Cowieson, AJ Horvath, AJ Quek, ... Cell reports 1 (3), 185-190, 2012 | 258 | 2012 |
New insights into the structure and function of the plasminogen/plasmin system RHP Law, D Abu-Ssaydeh, JC Whisstock Current opinion in structural biology 23 (6), 836-841, 2013 | 182 | 2013 |
Conformational changes during pore formation by the perforin-related protein pleurotolysin N Lukoyanova, SC Kondos, I Farabella, RHP Law, CF Reboul, ... PLoS biology 13 (2), e1002049, 2015 | 145 | 2015 |
Structure of the poly-C9 component of the complement membrane attack complex NV Dudkina, BA Spicer, CF Reboul, PJ Conroy, N Lukoyanova, ... Nature communications 7 (1), 10588, 2016 | 133 | 2016 |
The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins AJ Horvath, JA Irving, J Rossjohn, RH Law, SP Bottomley, NS Quinsey, ... Journal of Biological Chemistry 280 (52), 43168-43178, 2005 | 129 | 2005 |
X-ray crystal structure of the streptococcal specific phage lysin PlyC S McGowan, AM Buckle, MS Mitchell, JT Hoopes, DT Gallagher, ... Proceedings of the National Academy of Sciences 109 (31), 12752-12757, 2012 | 123 | 2012 |
Cloning and Expression of the Major SecretedCathepsin B-Like Protein from Juvenile Fasciola hepatica andAnalysis of Immunogenicity following Liver FlukeInfection RHP Law, PM Smooker, JA Irving, D Piedrafita, R Ponting, NJ Kennedy, ... Infection and immunity 71 (12), 6921-6932, 2003 | 122 | 2003 |
Optimal achieved blood pressure in acute intracerebral hemorrhage: INTERACT2 H Arima, E Heeley, C Delcourt, Y Hirakawa, X Wang, M Woodward, ... Neurology 84 (5), 464-471, 2015 | 121 | 2015 |
The structure and function of mammalian membrane‐attack complex/perforin‐like proteins SC Kondos, T Hatfaludi, I Voskoboinik, JA Trapani, RHP Law, ... Tissue Antigens 76 (5), 341-351, 2010 | 105 | 2010 |
The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates RM Kennan, W Wong, OP Dhungyel, X Han, D Wong, D Parker, ... PLoS pathogens 6 (11), e1001210, 2010 | 99 | 2010 |
The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix RHP Law, JA Irving, AM Buckle, K Ruzyla, M Buzza, ... Journal of Biological Chemistry 280 (23), 22356-22364, 2005 | 89 | 2005 |
[10] ATP synthase from Saccharomyces cerevisiae RHP Law, S Manon, RJ Devenish, P Nagley Methods in Enzymology 260, 133-163, 1995 | 75 | 1995 |
Inhibition of a K9/K36 demethylase by an H3. 3 point mutation found in paediatric glioblastoma HPJ Voon, M Udugama, W Lin, L Hii, RHP Law, DL Steer, PP Das, ... Nature communications 9 (1), 3142, 2018 | 74 | 2018 |
The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1 SS Pang, C Bayly-Jones, M Radjainia, BA Spicer, RHP Law, AW Hodel, ... Nature communications 10 (1), 4288, 2019 | 73 | 2019 |