Kenneth J. McDowall
Kenneth J. McDowall
Professor in Molecular Microbiology, University of Leeds
Verified email at - Homepage
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The regulation of the secondary metabolism of Streptomyces: new links and experimental advances
GP van Wezel, KJ McDowall
Natural product reports 28 (7), 1311-1333, 2011
A+ U content rather than a particular nucleotide order determines the specificity of RNase E cleavage.
KJ McDowall, S Lin-Chao, SN Cohen
Journal of Biological Chemistry 269 (14), 10790-10796, 1994
Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover
AJ Callaghan, MJ Marcaida, JA Stead, KJ McDowall, WG Scott, BF Luisi
Nature 437 (7062), 1187-1191, 2005
The N-terminal Domain of therneGene Product has RNase E Activity and is Non-overlapping with the Arginine-rich RNA-binding Site
KJ McDowall, SN Cohen
Journal of molecular biology 255 (3), 349-355, 1996
The CafA protein required for the 5′-maturation of 16 S rRNA is a 5′-end-dependent ribonuclease that has context-dependent broad sequence specificity
MR Tock, AP Walsh, G Carroll, KJ McDowall
Journal of Biological Chemistry 275 (12), 8726-8732, 2000
Transcriptional activation of the pathway‐specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor
GC Uguru, KE Stephens, JA Stead, JE Towle, S Baumberg, KJ McDowall
Molecular microbiology 58 (1), 131-150, 2005
Site-specific RNase E cleavage of oligonucleotides and inhibition by stem–loops
KJ McDowall, VR Kaberdin, SW Wu, SN Cohen, S Lin-Chao
Nature 374 (6519), 287-290, 1995
RNase E: still a wonderfully mysterious enzyme
SN Cohen, KJ McDowall
Molecular microbiology 23 (6), 1099-1106, 1997
Endonucleolytic initiation of mRNA decay in Escherichia coli
AJ Carpousis, BF Luisi, KJ McDowall
Progress in molecular biology and translational science 85, 91-135, 2009
Effects of nucleotide sequence on the specificity of rne-dependent and RNase E-mediated cleavages of RNA I encoded by the pBR322 plasmid.
S Lin-Chao, TT Wong, KJ McDowall, SN Cohen
Journal of Biological Chemistry 269 (14), 10797-10803, 1994
The endoribonucleolytic N-terminal half of Escherichia coli RNase E is evolutionarily conserved in Synechocystis sp. and other bacteria but not the C-terminal half, which is …
VR Kaberdin, A Miczak, JS Jakobsen, S Lin-Chao, KJ McDowall, ...
Proceedings of the National Academy of Sciences 95 (20), 11637-11642, 1998
The ams-1 and rne-3071 temperature-sensitive mutations in the ams gene are in close proximity to each other and cause substitutions within a domain that resembles a product of …
KJ McDOWALL, RG Hernandez, S Lin-Chao, SN Cohen
Journal of bacteriology 175 (13), 4245-4249, 1993
Regulation of antibiotic production in Actinobacteria: new perspectives from the post-genomic era
HU van der Heul, BL Bilyk, KJ McDowall, RF Seipke, GP van Wezel
Natural product reports 35 (6), 575-604, 2018
The permease gene nagE2 is the key to N‐acetylglucosamine sensing and utilization in Streptomyces coelicolor and is subject to multi‐level control
H Nothaft, S Rigali, B Boomsma, M Swiatek, KJ McDowall, GP Van Wezel, ...
Molecular microbiology 75 (5), 1133-1144, 2010
Characterization of an oxytetracycline‐resistance gene, otrA, of Streptomyces rimosus
D Doyle, KJ McDowall, MJ Butler, IS Hunter
Molecular microbiology 5 (12), 2923-2933, 1991
Quaternary structure and catalytic activity of the Escherichia coli ribonuclease E amino-terminal catalytic domain
AJ Callaghan, JG Grossmann, YU Redko, LL Ilag, MC Moncrieffe, ...
Biochemistry 42 (47), 13848-13855, 2003
Rapid cleavage of RNA by RNase E in the absence of 5′ monophosphate stimulation
L Kime, SS Jourdan, JA Stead, A Hidalgo‐Sastre, KJ McDowall
Molecular microbiology 76 (3), 590-604, 2010
Direct entry by RNase E is a major pathway for the degradation and processing of RNA in Escherichia coli
JE Clarke, L Kime, D Romero A, KJ McDowall
Nucleic acids research 42 (18), 11733-11751, 2014
Translational activation by the noncoding RNA DsrA involves alternative RNase III processing in the rpoS 5′-leader
A Resch, T Afonyushkin, TB Lombo, KJ McDowall, U Bläsi, VR Kaberdin
RNA 14 (3), 454-459, 2008
JOURNAL OF GENERAL MICROBIOLOGY 138 (11), 2465-2471, 1992
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