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Senani N.H. Rathnayake
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RAGE and TLR4 differentially regulate airway hyperresponsiveness: Implications for COPD
VSRR Allam, A Faiz, M Lam, SNH Rathnayake, B Ditz, SD Pouwels, ...
Allergy 76 (4), 1123-1135, 2021
202021
Cigarette smoke exposure alters phosphodiesterases in human structural lung cells
H Zuo, A Faiz, M Van den Berge, SNHR Mudiyanselage, T Borghuis, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 318 (1 …, 2020
172020
Current smoking alters gene expression and DNA methylation in the nasal epithelium of patients with asthma
KD Reddy, A Lan, IM Boudewijn, SNH Rathnayake, GH Koppelman, ...
American journal of respiratory cell and molecular biology 65 (4), 366-377, 2021
132021
Single-nucleotide polymorphism rs2070600 regulates AGER splicing and the sputum levels of the COPD biomarker soluble receptor for advanced glycation end-products
A Faiz, SNH Rathnayake, NHT Ten Hacken, V Guryev, M van den Berge, ...
ERJ open research 7 (2), 2021
92021
Differential lung tissue gene expression in males and females: implications for the susceptibility to develop COPD
M van den Berge, CA Brandsma, A Faiz, M de Vries, SNH Rathnayake, ...
European Respiratory Journal 54 (1), 1702567, 2019
92019
Genetic profiling for disease stratification in chronic obstructive pulmonary disease and asthma
SNH Rathnayake, M Van den Berge, A Faiz
Current opinion in pulmonary medicine 25 (3), 317-322, 2019
72019
Early transcriptional responses of bronchial epithelial cells to whole cigarette smoke mirror those of in-vivo exposed human bronchial mucosa
AM van der Does, RM Mahbub, DK Ninaber, SNH Rathnayake, W Timens, ...
Respiratory research 23 (1), 227, 2022
62022
Gene expression profiling of bronchial brushes is associated with the level of emphysema measured by computed tomography-based parametric response mapping
SNH Rathnayake, FAAM Hoesein, CJ Galban, NHT ten Hacken, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2020
62020
Smoking induces shifts in cellular composition and transcriptome within the bronchial mucus barrier
SNH Rathnayake, B Ditz, J van Nijnatten, T Sadaf, PM Hansbro, ...
Respirology 28 (2), 132-142, 2023
22023
Longitudinal Effects of 1-Year Smoking Cessation on Human Bronchial Epithelial Transcriptome
SNH Rathnayake, B Ditz, BWM Willemse, H Aliee, FJ Theis, MC Nawijn, ...
Chest 164 (1), 85-89, 2023
12023
Longitudinal effects of smoking cessation on DNA methylation in bronchial biopsies of COPD and asymptomatic smokers
A Faiz, SNH Rathnayake, C Vermeulen, W Timens, W Kooistra, B Oliver, ...
European Respiratory Journal 54 (suppl 63), 2019
12019
The ALDH3A1 gene suppresses Periostin gene expression in human airway epithelial cells exposed to cigarette smoke
S Rathnayake, K Reddy, D Xenaki, B Oliver, M Van Den Berge, A Faiz
European Respiratory Journal 62 (suppl 67), 2023
2023
Cigarette smoking, COPD and the sex chromosomes
KD Reddy, D Xenaki, S Rathnayake, R Zakarya, S Idrees, F Boedijono, ...
European Respiratory Journal 62 (suppl 67), 2023
2023
CRISPR single base-editing: in silico predictions to variant clonal cell lines
KA Dickson, N Field, T Blackman, Y Ma, T Xie, E Kurangil, S Idrees, ...
Human Molecular Genetics 32 (17), 2704-2716, 2023
2023
Influence of smoking on bronchial epithelial cell composition by cellular deconvolution and IHC
S Rathnayake, B Ditz, J Van Nijnatten, C Brandsma, W Timens, ...
European Respiratory Journal 60 (suppl 66), 2022
2022
The Y-chromosome regulates hallmark features of asthma and COPD
S Rathnayake, D Xenaki, A Faiz, B Oliver
European Respiratory Journal 60 (suppl 66), 2022
2022
Impact of smoking on bronchial-mucus barrier cellular composition and transcriptome
S Rathnayake, B Ditz, J van Nijnatten, P Hansbro, C Brandsma, W Timens, ...
RESPIROLOGY 27, 116-117, 2022
2022
Transcriptomic differences of the bronchial mucus barrier in COPD and healthy smokers compared to non-smokers
B Ditz, SNH Rathnayake, J van Nijnatten, T Sadaf, PM Hansbro, ...
Another step in COPD-endotyping, 29, 2022
2022
Current Smoking Affects Gene Expression and Methylation Patterns in Asthma Patient Nasal Epithelium
KD Reddy, IM Boudewijn, A Lan, S Rathnayake, GH Koppelman, B Oliver, ...
TP112. TP112 PROTEOMICS/GENOMICS/METABOLOMICS IN LUNG DISEASE, A4336-A4336, 2021
2021
LONGITUDINAL EFFECTS OF 12 MONTHS SMOKING CESSATION ON DNA METHYLATION AND GENE EXPRESSION IN BRONCHIAL BIOPSIES
S Rathnayake, C Vermeulen, N Ten Hacken, W Timens, W Kooistra, ...
RESPIROLOGY 26, 118-118, 2021
2021
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