| Recent advances in cancer therapy targeting proteins involved in DNA double-strand break repair E Bolderson, DJ Richard, BBS Zhou, KK Khanna Clinical Cancer Research 15 (20), 6314-6320, 2009 | 219 | 2009 |
| Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature MP Barr, SG Gray, AC Hoffmann, RA Hilger, J Thomale, JD O’Flaherty, ... PloS one 8 (1), e54193, 2013 | 218 | 2013 |
| Single-stranded DNA-binding protein hSSB1 is critical for genomic stability DJ Richard, E Bolderson, L Cubeddu, RIM Wadsworth, K Savage, ... Nature 453 (7195), 677-681, 2008 | 217 | 2008 |
| Combination therapy with histone deacetylase inhibitors (HDACi) for the treatment of cancer: achieving the full therapeutic potential of HDACi A Suraweera, KJ O’Byrne, DJ Richard Frontiers in oncology 8, 92, 2018 | 211 | 2018 |
| Functions and therapeutic roles of exosomes in cancer JA Tickner, AJ Urquhart, SA Stephenson, DJ Richard, KJ O’Byrne Frontiers in oncology 4, 127, 2014 | 192 | 2014 |
| Circulating tumour cells, their role in metastasis and their clinical utility in lung cancer JD O’Flaherty, S Gray, JJ O’Leary, FH Blackhall, KJ O’Byrne Lung Cancer, 2011 | 172 | 2011 |
| Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks E Bolderson, N Tomimatsu, DJ Richard, D Boucher, R Kumar, TK Pandita, ... Nucleic acids research 38 (6), 1821-1831, 2010 | 168 | 2010 |
| Transcriptional regulation in response to oxygen and nitrate of the operons encoding the [NiFe] hydrogenases 1 and 2 of Escherichia coli DJ Richard, G Sawers, F Sargent, L McWalter, DH Boxer Microbiology 145 (10), 2903-2912, 1999 | 120 | 1999 |
| Nucleophosmin: from structure and function to disease development JK Box, N Paquet, MN Adams, D Boucher, E Bolderson, KJ O’Byrne, ... BMC molecular biology 17 (1), 1-12, 2016 | 118 | 2016 |
| Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability KI Savage, JJ Gorski, EM Barros, GW Irwin, L Manti, AJ Powell, ... Molecular cell 54 (3), 445-459, 2014 | 115 | 2014 |
| The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy JD O’Flaherty, M Barr, D Fennell, D Richard, J Reynolds, J O’Leary, ... Journal of thoracic oncology 7 (12), 1880-1890, 2012 | 111 | 2012 |
| Par4 is a coactivator for a splice isoform–specific transcriptional activation domain in WT1 DJ Richard, V Schumacher, B Royer-Pokora, SGE Roberts Genes & development 15 (3), 328-339, 2001 | 109 | 2001 |
| The role of DNA repair pathways in cisplatin resistant lung cancer S O’Grady, SP Finn, S Cuffe, DJ Richard, KJ O’Byrne, MP Barr Cancer treatment reviews 40 (10), 1161-1170, 2014 | 103 | 2014 |
| BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability KI Savage, KB Matchett, EM Barros, KM Cooper, GW Irwin, JJ Gorski, ... Cancer research 74 (10), 2773-2784, 2014 | 97 | 2014 |
| Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis DJ Richard, E Bolderson, KK Khanna Critical reviews in biochemistry and molecular biology 44 (2-3), 98-116, 2009 | 94 | 2009 |
| Structure of Hjc, a Holliday junction resolvase, from Sulfolobus solfataricus CS Bond, M Kvaratskhelia, D Richard, MF White, WN Hunter Proceedings of the National Academy of Sciences 98 (10), 5509-5514, 2001 | 94 | 2001 |
| HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response Y Li, E Bolderson, R Kumar, PA Muniandy, Y Xue, DJ Richard, ... Journal of Biological Chemistry 284 (35), 23525-23531, 2009 | 93 | 2009 |
| Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising C Jekimovs, E Bolderson, A Suraweera, M Adams, KJ O’Byrne, ... Frontiers in oncology 4, 86, 2014 | 88 | 2014 |
| INTS3 controls the hSSB1-mediated DNA damage response JR Skaar, DJ Richard, A Saraf, A Toschi, E Bolderson, L Florens, ... Journal of Cell Biology 187 (1), 25-32, 2009 | 77 | 2009 |
| hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex DJ Richard, K Savage, E Bolderson, L Cubeddu, S So, M Ghita, DJ Chen, ... Nucleic acids research 39 (5), 1692-1702, 2011 | 73 | 2011 |
o'byrne kSt James's Hospital and Trinity College, Dublin, IrelandVerified email at eircom.net
