|Recent advances in cancer therapy targeting proteins involved in DNA double-strand break repair|
E Bolderson, DJ Richard, BBS Zhou, KK Khanna
Clinical Cancer Research 15 (20), 6314-6320, 2009
|Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature|
MP Barr, SG Gray, AC Hoffmann, RA Hilger, J Thomale, JD O’Flaherty, ...
PloS one 8 (1), e54193, 2013
|Single-stranded DNA-binding protein hSSB1 is critical for genomic stability|
DJ Richard, E Bolderson, L Cubeddu, RIM Wadsworth, K Savage, ...
Nature 453 (7195), 677-681, 2008
|Combination therapy with histone deacetylase inhibitors (HDACi) for the treatment of cancer: achieving the full therapeutic potential of HDACi|
A Suraweera, KJ O’Byrne, DJ Richard
Frontiers in oncology 8, 92, 2018
|Functions and therapeutic roles of exosomes in cancer|
JA Tickner, AJ Urquhart, SA Stephenson, DJ Richard, KJ O’Byrne
Frontiers in oncology 4, 127, 2014
|Circulating tumour cells, their role in metastasis and their clinical utility in lung cancer|
JD O’Flaherty, S Gray, JJ O’Leary, FH Blackhall, KJ O’Byrne
Lung Cancer, 2011
|Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks|
E Bolderson, N Tomimatsu, DJ Richard, D Boucher, R Kumar, TK Pandita, ...
Nucleic acids research 38 (6), 1821-1831, 2010
|Transcriptional regulation in response to oxygen and nitrate of the operons encoding the [NiFe] hydrogenases 1 and 2 of Escherichia coli|
DJ Richard, G Sawers, F Sargent, L McWalter, DH Boxer
Microbiology 145 (10), 2903-2912, 1999
|Nucleophosmin: from structure and function to disease development|
JK Box, N Paquet, MN Adams, D Boucher, E Bolderson, KJ O’Byrne, ...
BMC molecular biology 17 (1), 1-12, 2016
|Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability|
KI Savage, JJ Gorski, EM Barros, GW Irwin, L Manti, AJ Powell, ...
Molecular cell 54 (3), 445-459, 2014
|The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy|
JD O’Flaherty, M Barr, D Fennell, D Richard, J Reynolds, J O’Leary, ...
Journal of thoracic oncology 7 (12), 1880-1890, 2012
|Par4 is a coactivator for a splice isoform–specific transcriptional activation domain in WT1|
DJ Richard, V Schumacher, B Royer-Pokora, SGE Roberts
Genes & development 15 (3), 328-339, 2001
|The role of DNA repair pathways in cisplatin resistant lung cancer|
S O’Grady, SP Finn, S Cuffe, DJ Richard, KJ O’Byrne, MP Barr
Cancer treatment reviews 40 (10), 1161-1170, 2014
|BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability|
KI Savage, KB Matchett, EM Barros, KM Cooper, GW Irwin, JJ Gorski, ...
Cancer research 74 (10), 2773-2784, 2014
|Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis|
DJ Richard, E Bolderson, KK Khanna
Critical reviews in biochemistry and molecular biology 44 (2-3), 98-116, 2009
|Structure of Hjc, a Holliday junction resolvase, from Sulfolobus solfataricus|
CS Bond, M Kvaratskhelia, D Richard, MF White, WN Hunter
Proceedings of the National Academy of Sciences 98 (10), 5509-5514, 2001
|HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response|
Y Li, E Bolderson, R Kumar, PA Muniandy, Y Xue, DJ Richard, ...
Journal of Biological Chemistry 284 (35), 23525-23531, 2009
|Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising|
C Jekimovs, E Bolderson, A Suraweera, M Adams, KJ O’Byrne, ...
Frontiers in oncology 4, 86, 2014
|INTS3 controls the hSSB1-mediated DNA damage response|
JR Skaar, DJ Richard, A Saraf, A Toschi, E Bolderson, L Florens, ...
Journal of Cell Biology 187 (1), 25-32, 2009
|hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex|
DJ Richard, K Savage, E Bolderson, L Cubeddu, S So, M Ghita, DJ Chen, ...
Nucleic acids research 39 (5), 1692-1702, 2011