Serpin inhibition mechanism: a delicate balance between native metastable state and polymerization MS Khan, P Singh, A Azhar, A Naseem, Q Rashid, MA Kabir, ... Journal of amino acids 2011, 2011 | 107 | 2011 |
Laser therapy inhibits tumor growth in mice by promoting immune surveillance and vessel normalization G Ottaviani, V Martinelli, K Rupel, N Caronni, A Naseem, L Zandonà, ... EBioMedicine 11, 165-172, 2016 | 67 | 2016 |
Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation H Ali, M Mano, L Braga, A Naseem, B Marini, DM Vu, C Collesi, G Meroni, ... Nature communications 10 (1), 926, 2019 | 49 | 2019 |
Neutrophils drive type I interferon production and autoantibodies in patients with Wiskott-Aldrich syndrome KE Cervantes-Luevano, N Caronni, MC Castiello, E Fontana, GM Piperno, ... Journal of Allergy and Clinical Immunology 142 (5), 1605-1617. e4, 2018 | 21 | 2018 |
Antiangiogenic function of antithrombin is dependent on its conformational variation: implication for other serpins A Azhar, P Singh, Q Rashid, A Naseem, M Sazzad Khan, ... Protein and Peptide Letters 20 (4), 403-411, 2013 | 21 | 2013 |
Wiskott-Aldrich syndrome protein restricts cGAS/STING activation by dsDNA immune complexes GM Piperno, A Naseem, G Silvestrelli, R Amadio, N Caronni, ... JCI insight 5 (17), 2020 | 13 | 2020 |
Elucidating the specificity of non-heparin-based conformational activators of antithrombin for factor Xa inhibition Q Rashid, M Abid, MA Jairajpuri Journal of Natural Science, Biology, and Medicine 5 (1), 36, 2014 | 12 | 2014 |
Catechol biodegradation by Pseudomonas strain: a critical analysis M Zeyaullah, R Ahmad, A Naseem, B Islam, HMI Hasan, AS Abdelkafe, ... Int. J. Chem. Sci 7 (3), 2211-2221, 2009 | 12 | 2009 |
Deciphering the role of trehalose in hindering antithrombin polymerization A Naseem, MS Khan, H Ali, I Ahmad, MA Jairajpuri Bioscience Reports 39 (4), BSR20182259, 2019 | 9 | 2019 |
Oxidized antithrombin is a dual inhibitor of coagulation and angiogenesis: importance of low heparin affinity A Azhar, MS Khan, A Swaminathan, A Naseem, S Chatterjee, ... International journal of biological macromolecules 82, 541-550, 2016 | 9 | 2016 |
Genome editing for primary immunodeficiencies: A therapeutic perspective on Wiskott-Aldrich syndrome A Naseem, Z Steinberg, A Cavazza Frontiers in Immunology 13, 966084, 2022 | 7 | 2022 |
An improved medium formulation for efficient ex vivo gene editing, expansion and engraftment of hematopoietic stem and progenitor cells R Rai, A Naseem, W Vetharoy, Z Steinberg, AJ Thrasher, G Santilli, ... Molecular Therapy-Methods & Clinical Development 29, 58-69, 2023 | 5 | 2023 |
Analysis of surface cavity in serpin family reveals potential binding sites for chemical chaperone to reduce polymerization P Singh, MS Khan, A Naseem, MA Jairajpuri Journal of molecular modeling 18, 1143-1151, 2012 | 4 | 2012 |
Optimized cell culture conditions promote ex-vivo manipulation and expansion of primitive hematopoietic stem cells for therapeutic gene editing R Rai, W Vetharoy, A Naseem, Z Steinberg, AJ Thrasher, G Santilli, ... bioRxiv, 2022.01. 11.475795, 2022 | 2 | 2022 |
Multidimensional Response Surface Methodology for the Development of a Gene Editing Protocol for p67phox-Deficient Chronic Granulomatous Disease TE Whittaker, SE Moula, S Bahal, FG Bakri, WA Hayajneh, AK Daoud, ... Human Gene Therapy, 2024 | 1 | 2024 |
SARS-CoV-2 Syncytium under the radar: molecular insights of the spike-induced syncytia and potential strategies to limit SARS-CoV-2 replication H Ali, A Naseem, ZI Siddiqui Journal of Clinical Medicine 12 (18), 6079, 2023 | 1 | 2023 |
Preclinical Safety and Feasibility Study of a CRISPR/Cas9 Gene Editing Platform to Treat Wiskott Aldrich Syndrome A Naseem, R Rai, G Turchiano, T Whittaker, AJ Thrasher, A Cavazza MOLECULAR THERAPY 30 (4), 34-34, 2022 | 1 | 2022 |
Preclinical studies for a hematopoietic stem cell gene editing platform to treat Wiskott-Aldrich Syndrome. A Naseem, W Vetharoy, R Rai, TE Whittaker, G Turchiano, AJ Thrasher, ... HUMAN GENE THERAPY 32 (19-20), A72-A72, 2021 | 1 | 2021 |
It’s all about location: Targeting the right spot for Wiskott-Aldrich syndrome A Naseem, A Cavazza Molecular Therapy Methods & Clinical Development 32 (2), 2024 | | 2024 |
Hematopoietic stem cell gene editing rescues B-cell development in X-linked agammaglobulinemia S Bahal, M Zinicola, SE Moula, TE Whittaker, A Schejtman, A Naseem, ... Journal of Allergy and Clinical Immunology, 2024 | | 2024 |