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Sandeep Chhabra
Sandeep Chhabra
Verified email at amgen.com
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Year
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation
J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ...
Cancer discovery 8 (2), 216-233, 2018
5742018
DOTA-amide lanthanide tag for reliable generation of pseudocontact shifts in protein NMR spectra
B Graham, CT Loh, JD Swarbrick, P Ung, J Shin, H Yagi, X Jia, S Chhabra, ...
Bioconjugate chemistry 22 (10), 2118-2125, 2011
1342011
Aromatic 19F-13C TROSY: a background-free approach to probe biomolecular structure, function, and dynamics
A Boeszoermenyi, S Chhabra, A Dubey, DL Radeva, NT Burdzhiev, ...
Nature methods 16 (4), 333-340, 2019
902019
A potent and Kv1. 3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases
MH Rashid, R Huq, MR Tanner, S Chhabra, KK Khoo, R Estrada, ...
Scientific reports 4 (1), 4509, 2014
902014
Kv1. 3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases
S Chhabra, SC Chang, HM Nguyen, R Huq, MR Tanner, LM Londono, ...
The FASEB Journal 28 (9), 3952, 2014
882014
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation. Cancer Discov. 2018; 8: 216–233. doi: 10.1158/2159-8290
J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ...
CD-17-0915.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
83
VPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteins
JD Swarbrick, DJ Shaw, S Chhabra, R Ghai, E Valkov, SJ Norwood, ...
PLoS One 6 (5), e20420, 2011
692011
Development of highly selective Kv1. 3-blocking peptides based on the sea anemone peptide ShK
MW Pennington, SC Chang, S Chauhan, R Huq, RB Tajhya, S Chhabra, ...
Marine Drugs 13 (1), 529-542, 2015
682015
A potent and selective peptide blocker of the Kv1. 3 channel: prediction from free-energy simulations and experimental confirmation
MH Rashid, G Heinzelmann, R Huq, RB Tajhya, SC Chang, S Chhabra, ...
PloS one 8 (11), e78712, 2013
682013
A novel inhibitor of α9α10 nicotinic acetylcholine receptors from Conus vexillum delineates a new conotoxin superfamily
S Luo, S Christensen, D Zhangsun, Y Wu, Y Hu, X Zhu, S Chhabra, ...
PloS one 8 (1), e54648, 2013
672013
Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets
S Chhabra, A Belgi, P Bartels, BJ van Lierop, SD Robinson, SN Kompella, ...
Journal of Medicinal Chemistry 57 (23), 9933-9944, 2014
662014
An iminodiacetic acid based lanthanide binding tag for paramagnetic exchange NMR spectroscopy
JD Swarbrick, P Ung, S Chhabra, B Graham
Angewandte Chemie 19 (123), 4495-4498, 2011
622011
15N detection harnesses the slow relaxation property of nitrogen: Delivering enhanced resolution for intrinsically disordered proteins
S Chhabra, P Fischer, K Takeuchi, A Dubey, JJ Ziarek, A Boeszoermenyi, ...
Proceedings of the National Academy of Sciences 115 (8), E1710-E1719, 2018
572018
Engineering of a bis-chelator motif into a protein α-helix for rigid lanthanide binding and paramagnetic NMR spectroscopy
JD Swarbrick, P Ung, XC Su, A Maleckis, S Chhabra, T Huber, G Otting, ...
Chemical communications 47 (26), 7368-7370, 2011
542011
Compact, hydrophilic, lanthanide-binding tags for paramagnetic NMR spectroscopy
MD Lee, CT Loh, J Shin, S Chhabra, ML Dennis, G Otting, JD Swarbrick, ...
Chemical Science 6 (4), 2614-2624, 2015
442015
8‐Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase
ML Dennis, MD Lee, JR Harjani, M Ahmed, AJ DeBono, NP Pitcher, ...
Chemistry–A European Journal 24 (8), 1922-1930, 2018
412018
N‐terminally extended analogues of the K+ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage‐gated potassium channel …
SC Chang, R Huq, S Chhabra, C Beeton, MW Pennington, BJ Smith, ...
The FEBS journal 282 (12), 2247-2259, 2015
382015
A potent cyclic peptide targeting SPSB2 protein as a potential anti-infective agent
BK Yap, EWW Leung, H Yagi, CA Galea, S Chhabra, DK Chalmers, ...
Journal of Medicinal Chemistry 57 (16), 7006-7015, 2014
342014
Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor
S Chhabra, O Dolezal, BM Collins, J Newman, JS Simpson, IG Macreadie, ...
PloS one 7 (1), e29444, 2012
322012
Exploring the chemical space around 8-mercaptoguanine as a route to new inhibitors of the folate biosynthesis enzyme HPPK
S Chhabra, N Barlow, O Dolezal, MK Hattarki, J Newman, TS Peat, ...
PloS one 8 (4), e59535, 2013
232013
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