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Lim Kah Leong
Lim Kah Leong
Nanyang Technological University, National University of Singapore, National Neuroscience Institute
Verified email at nus.edu.sg
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Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13055*2021
Parkin ubiquitinates the α-synuclein–interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease
KKK Chung, Y Zhang, KL Lim, Y Tanaka, H Huang, J Gao, CA Ross, ...
Nature medicine 7 (10), 1144-1150, 2001
9682001
Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity
AB West, DJ Moore, C Choi, SA Andrabi, X Li, D Dikeman, S Biskup, ...
Human molecular genetics 16 (2), 223-232, 2007
6962007
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation
KL Lim, KCM Chew, JMM Tan, C Wang, KKK Chung, Y Zhang, Y Tanaka, ...
Journal of Neuroscience 25 (8), 2002-2009, 2005
6242005
Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
JY Lee, Y Nagano, JP Taylor, KL Lim, TP Yao
Journal of Cell Biology 189 (4), 671-679, 2010
6222010
Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases
JMM Tan, ESP Wong, DS Kirkpatrick, O Pletnikova, HS Ko, SP Tay, ...
Human molecular genetics 17 (3), 431-439, 2008
5282008
Loss of locus coeruleus neurons and reduced startle in parkin null mice
R Von Coelln, B Thomas, JM Savitt, KL Lim, M Sasaki, EJ Hess, ...
Proceedings of the National Academy of Sciences 101 (29), 10744-10749, 2004
4072004
Intraparticle Energy Level Alignment of Semiconducting Polymer Nanoparticles to Amplify Chemiluminescence for Ultrasensitive In Vivo Imaging of Reactive …
X Zhen, C Zhang, C Xie, Q Miao, KL Lim, K Pu
ACS nano 10 (6), 6400-6409, 2016
2862016
Targeted disruption of the tyrosine phosphatase PTPα leads to constitutive downregulation of the kinases Src and Fyn
S Ponniah, DZM Wang, KL Lim, CJ Pallen
Current Biology 9 (10), 535-538, 1999
2671999
Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila
CH Ng, SZS Mok, C Koh, X Ouyang, ML Fivaz, EK Tan, VL Dawson, ...
Journal of Neuroscience 29 (36), 11257-11262, 2009
2432009
Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function
C Wang, HS Ko, B Thomas, F Tsang, KCM Chew, SP Tay, MWL Ho, ...
Human molecular genetics 14 (24), 3885-3897, 2005
2432005
Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin
SR Sriram, X Li, HS Ko, KKK Chung, E Wong, KL Lim, VL Dawson, ...
Human molecular genetics 14 (17), 2571-2586, 2005
2412005
Reactive oxygen species trigger Parkin/PINK1 pathway–dependent mitophagy by inducing mitochondrial recruitment of Parkin
B Xiao, JY Goh, L Xiao, H Xian, KL Lim, YC Liou
Journal of Biological Chemistry 292 (40), 16697-16708, 2017
2032017
Autophagy-mediated clearance of aggresomes is not a universal phenomenon
ESP Wong, JMM Tan, WE Soong, K Hussein, N Nukina, VL Dawson, ...
Human molecular genetics 17 (16), 2570-2582, 2008
1902008
AMP kinase activation mitigates dopaminergic dysfunction and mitochondrial abnormalities in Drosophila models of Parkinson's disease
CH Ng, MSH Guan, C Koh, X Ouyang, F Yu, EK Tan, SP O'Neill, X Zhang, ...
Journal of Neuroscience 32 (41), 14311-14317, 2012
1872012
A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson’s disease models
L Li, CW Zhang, GYJ Chen, B Zhu, C Chai, QH Xu, EK Tan, Q Zhu, KL Lim, ...
Nature Communications 5 (1), 3276, 2014
1862014
Deregulation of a STAT3–interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness
N De La Iglesia, G Konopka, KL Lim, CL Nutt, JF Bromberg, DA Frank, ...
Journal of Neuroscience 28 (23), 5870-5878, 2008
1802008
Role of the ubiquitin proteasome system in Parkinson's disease
KL Lim, JMM Tan
BMC biochemistry 8, 1-10, 2007
1762007
Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age
AC Pawlyk, BI Giasson, DM Sampathu, FA Perez, KL Lim, VL Dawson, ...
Journal of Biological Chemistry 278 (48), 48120-48128, 2003
1762003
Parkin-mediated lysine 63-linked polyubiquitination: a link to protein inclusions formation in Parkinson's and other conformational diseases?
KL Lim, VL Dawson, TM Dawson
Neurobiology of aging 27 (4), 524-529, 2006
1662006
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