Yafeng Xue
Yafeng Xue
Unknown affiliation
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418
R Bhat, Y Xue, S Berg, S Hellberg, M Ormö, Y Nilsson, AC Radesäter, ...
Journal of Biological Chemistry 278 (46), 45937-45945, 2003
5072003
Inhibition and catalysis of carbonic anhydrase
A LILJAS, K HÅKANSSON, BH JONSSON, Y XUE
European journal of biochemistry 219 (1‐2), 1-10, 1994
1671994
Exploitation of structural and regulatory diversity in glutamate racemases
T Lundqvist, SL Fisher, G Kern, RHA Folmer, Y Xue, DT Newton, ...
Nature 447 (7146), 817-822, 2007
1382007
Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop …
Y Xue, P Björquist, T Inghardt, M Linschoten, D Musil, L Sjölin, J Deinum
Structure 6 (5), 627-636, 1998
1201998
Crystal structure of spinach plastocyanin at 1.7 Å resolution
Y Xue, M Ökvist, Ö Hansson, S Young
Protein science 7 (10), 2099-2105, 1998
1141998
Discovery of novel potent and highly selective glycogen synthase kinase-3β (GSK3β) inhibitors for Alzheimer’s disease: design, synthesis, and characterization of pyrazines
S Berg, M Bergh, S Hellberg, K Högdin, Y Lo-Alfredsson, P Söderman, ...
Journal of medicinal chemistry 55 (21), 9107-9119, 2012
1062012
Crystallographic analysis of Thr‐200→ His human carbonic anhydrase II and its complex with the substrate, HCO3−
Y Xue, J Vidgren, LA Svensson, A Liljas, BH Jonsson, S Lindskog
Proteins: Structure, Function, and Bioinformatics 15 (1), 80-87, 1993
1041993
Hit-to-lead studies: the discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors
A Baxter, S Brough, A Cooper, E Floettmann, S Foster, C Harding, J Kettle, ...
Bioorganic & Medicinal Chemistry Letters 14 (11), 2817-2822, 2004
1032004
Importance of the conserved active‐site residues Try7, Glu106 and Thr199 for the catalytic function of human carbonic anhydrase II
Z LIANG, Y XUE, G BEHRAVAN, BH JONSSON, S LINDSKOG
European Journal of Biochemistry 211 (3), 821-827, 1993
1011993
Crystal structure of spinach chloroplast fructose-1, 6-bisphosphatase at 2.8. ANG. resolution
V Villeret, S Huang, Y Zhang, Y Xue, WN Lipscomb
Biochemistry 34 (13), 4299-4306, 1995
951995
Crystal structure of carbonic anhydrase from Neisseria gonorrhoeae and its complex with the inhibitor acetazolamide
S Huang, Y Xue, E Sauer-Eriksson, L Chirica, S Lindskog, BH Jonsson
Journal of molecular biology 283 (1), 301-310, 1998
941998
Crystal structure of fructose-1, 6-bisphosphatase complexed with fructose 2, 6-bisphosphate, AMP, and Zn2+ at 2.0-A resolution: aspects of synergism between inhibitors
Y Xue, S Huang, JY Liang, Y Zhang, WN Lipscomb
Proceedings of the National Academy of Sciences 91 (26), 12482-12486, 1994
941994
The crystal structure of allosteric chorismate mutase at 2.2-A resolution
Y Xue, WN Lipscomb, R Graf, G Schnappauf, G Braus
Proceedings of the National Academy of Sciences 91 (23), 10814-10818, 1994
891994
Structural analysis of the zinc hydroxide–Thr‐199–Glu‐106 hydrogen‐bond network in human carbonic anhydrase II
Y Xue, A Liljas, BH Jonsson, S Lindskog
Proteins: Structure, Function, and Bioinformatics 17 (1), 93-106, 1993
861993
Total synthesis and structural confirmation of chlorodysinosin A
S Hanessian, JR Del Valle, Y Xue, N Blomberg
Journal of the American Chemical Society 128 (32), 10491-10495, 2006
742006
A strategically positioned cation is crucial for efficient catalysis by chorismate mutase
P Kast, C Grisostomi, IA Chen, S Li, U Krengel, Y Xue, D Hilvert
Journal of Biological Chemistry 275 (47), 36832-36838, 2000
702000
Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa
MS Buchanan, AR Carroll, D Wessling, M Jobling, VM Avery, RA Davis, ...
Journal of medicinal chemistry 51 (12), 3583-3587, 2008
692008
Design and synthesis of 6-anilinoindazoles as selective inhibitors of c-Jun N-terminal kinase-3
BM Swahn, F Huerta, E Kallin, J Malmström, T Weigelt, J Viklund, ...
Bioorganic & medicinal chemistry letters 15 (22), 5095-5099, 2005
652005
Crystal structure of the native plasminogen reveals an activation‐resistant compact conformation
Y Xue, C Bodin, K Olsson
Journal of Thrombosis and Haemostasis 10 (7), 1385-1396, 2012
582012
Discovery of Checkpoint Kinase Inhibitor (S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by Structure-Based Design and …
V Oza, S Ashwell, L Almeida, P Brassil, J Breed, C Deng, T Gero, ...
Journal of medicinal chemistry 55 (11), 5130-5142, 2012
562012
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