| The Akt–SREBP nexus: cell signaling meets lipid metabolism JR Krycer, LJ Sharpe, W Luu, AJ Brown Trends in Endocrinology & Metabolism 21 (5), 268-276, 2010 | 358 | 2010 |
| DHCR7: A vital enzyme switch between cholesterol and vitamin D production AV Prabhu, W Luu, D Li, LJ Sharpe, AJ Brown Progress in lipid research 64, 138-151, 2016 | 159 | 2016 |
| Oxysterols: old tale, new twists W Luu, LJ Sharpe, I Capell-Hattam, IC Gelissen, AJ Brown Annual review of pharmacology and toxicology 56, 447-467, 2016 | 139 | 2016 |
| Cholesterol-mediated degradation of 7-dehydrocholesterol reductase switches the balance from cholesterol to vitamin D synthesis AV Prabhu, W Luu, LJ Sharpe, AJ Brown Journal of Biological Chemistry 291 (16), 8363-8373, 2016 | 133 | 2016 |
| The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally [S] W Luu, G Hart-Smith, LJ Sharpe, AJ Brown Journal of lipid research 56 (4), 888-897, 2015 | 81 | 2015 |
| Akt acutely activates the cholesterogenic transcription factor SREBP-2 W Luu, LJ Sharpe, J Stevenson, AJ Brown Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (2), 458-464, 2012 | 72 | 2012 |
| Akt phosphorylates Sec24: new clues into the regulation of ER‐to‐Golgi trafficking LJ Sharpe, W Luu, AJ Brown Traffic 12 (1), 19-27, 2011 | 72 | 2011 |
| The role of signalling in cellular cholesterol homeostasis W Luu, LJ Sharpe, IC Gelissen, AJ Brown IUBMB life 65 (8), 675-684, 2013 | 67 | 2013 |
| Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesis [S] W Luu, EJ Zerenturk, I Kristiana, MP Bucknall, LJ Sharpe, AJ Brown Journal of lipid research 55 (3), 410-420, 2014 | 65 | 2014 |
| Squalene mono-oxygenase, a key enzyme in cholesterol synthesis, is stabilized by unsaturated fatty acids J Stevenson, W Luu, I Kristiana, AJ Brown Biochemical Journal 461 (3), 435-442, 2014 | 42 | 2014 |
| Cholesterol increases protein levels of the E3 ligase MARCH6 and thereby stimulates protein degradation LJ Sharpe, V Howe, NA Scott, W Luu, L Phan, JM Berk, M Hochstrasser, ... Journal of Biological Chemistry 294 (7), 2436-2448, 2019 | 39 | 2019 |
| Phosphorylation regulates activity of 7-dehydrocholesterol reductase (DHCR7), a terminal enzyme of cholesterol synthesis AV Prabhu, W Luu, LJ Sharpe, AJ Brown The Journal of Steroid Biochemistry and Molecular Biology 165, 363-368, 2017 | 36 | 2017 |
| Cholesterol through the looking glass: ability of its enantiomer also to elicit homeostatic responses I Kristiana, W Luu, J Stevenson, S Cartland, W Jessup, JD Belani, ... Journal of Biological Chemistry 287 (40), 33897-33904, 2012 | 35 | 2012 |
| The cholesterol synthesis enzyme lanosterol 14α-demethylase is post-translationally regulated by the E3 ubiquitin ligase MARCH6 NA Scott, LJ Sharpe, IM Capell-Hattam, SJ Gullo, W Luu, AJ Brown Biochemical Journal 477 (2), 541-555, 2020 | 28 | 2020 |
| Manipulating cholesterol status within cells W Luu, IC Gelissen, AJ Brown Cholesterol Homeostasis: Methods and Protocols, 41-52, 2017 | 14 | 2017 |
| Cholesterol synthesis enzyme SC4MOL is fine-tuned by sterols and targeted for degradation by the E3 ligase MARCHF6 L Qian, NA Scott, IM Capell-Hattam, EA Draper, NM Fenton, W Luu, ... Journal of Lipid Research 64 (5), 2023 | 7 | 2023 |
| Navigating the shallows and rapids of cholesterol synthesis downstream of HMGCR LJ Sharpe, V Howe, AV Prabhu, W Luu, AJ Brown Journal of nutritional science and vitaminology 61 (Supplement), S154-S156, 2015 | 5 | 2015 |
| Protein tyrosine phosphatase inhibition down-regulates ligand-induced ABCA1 expression W Luu, LJ Sharpe, AJ Brown Atherosclerosis 228 (2), 362-369, 2013 | 5 | 2013 |
| Measuring activity of cholesterol synthesis enzymes using gas chromatography/mass spectrometry AV Prabhu, W Luu, AJ Brown Cholesterol Homeostasis: Methods and Protocols, 211-219, 2017 | 3 | 2017 |
| Cholesterol‐Mediated Degradation of 7‐Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis LJ Sharpe, AV Prabhu, W Luu, AJ Brown The FASEB Journal 30, 1064.1-1064.1, 2016 | 1 | 2016 |
Laura SharpeUniversity of New South WalesVerified email at unsw.edu.au
