Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons PG Hendrickson, JA Doráis, EJ Grow, JL Whiddon, JW Lim, CL Wike, ... Nature genetics 49 (6), 925-934, 2017 | 623 | 2017 |
Alterations in sperm DNA methylation patterns at imprinted loci in two classes of infertility SS Hammoud, J Purwar, C Pflueger, BR Cairns, DT Carrell Fertility and sterility 94 (5), 1728-1733, 2010 | 340 | 2010 |
Age-associated sperm DNA methylation alterations: possible implications in offspring disease susceptibility TG Jenkins, KI Aston, C Pflueger, BR Cairns, DT Carrell PLoS genetics 10 (7), e1004458, 2014 | 313 | 2014 |
A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs C Pflueger, D Tan, T Swain, T Nguyen, J Pflueger, C Nefzger, JM Polo, ... Genome research 28 (8), 1193-1206, 2018 | 154 | 2018 |
Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution CA Herring, RK Simmons, S Freytag, D Poppe, JJD Moffet, J Pflueger, ... Cell 185 (23), 4428-4447. e28, 2022 | 55 | 2022 |
Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription S Ramakrishnan, S Pokhrel, S Palani, C Pflueger, TJ Parnell, BR Cairns, ... Nature communications 7 (1), 11949, 2016 | 52 | 2016 |
Synthetic memory circuits for stable cell reprogramming in plants JPB Lloyd, F Ly, P Gong, J Pflueger, T Swain, C Pflueger, E Fourie, ... Nature biotechnology 40 (12), 1862-1872, 2022 | 39 | 2022 |
Interaction of the Jhd2 histone H3 Lys-4 demethylase with chromatin is controlled by histone H2A surfaces and restricted by H2B ubiquitination F Huang, S Ramakrishnan, S Pokhrel, C Pflueger, TJ Parnell, MM Kasten, ... Journal of Biological Chemistry 290 (48), 28760-28777, 2015 | 21 | 2015 |
Harnessing targeted DNA methylation and demethylation using dCas9 C Pflueger, T Swain, R Lister Essays in Biochemistry 63 (6), 813-825, 2019 | 14 | 2019 |
CRISPRi-based circuits for genetic computation in plants MA Khan, G Herring, M Oliva, E Fourie, JY Zhu, B Johnston, J Pflüger, ... BioRxiv, 2022.07. 01.498372, 2022 | 10 | 2022 |
Synthetic Epigenetic Reprogramming of Mesenchymal to Epithelial States Using the CRISPR/dCas9 Platform in Triple Negative Breast Cancer C Waryah, J Cursons, M Foroutan, C Pflueger, E Wang, R Molania, ... Advanced Science 10 (22), 2301802, 2023 | 9 | 2023 |
Hypermethylation of circulating free DNA in cutaneous melanoma RJ Diefenbach, JH Lee, D Chandler, Y Wang, C Pflueger, GV Long, ... Applied Sciences 9 (23), 5074, 2019 | 6 | 2019 |
A modular dCas9-based recruitment platform for combinatorial epigenome editing T Swain, C Pflueger, S Freytag, D Poppe, J Pflueger, TV Nguyen, JK Li, ... Nucleic Acids Research 52 (1), 474-491, 2024 | 3 | 2024 |
Synthetic memory circuits for programmable cell reconfiguration in plants JPB Lloyd, F Ly, P Gong, J Pflüger, T Swain, C Pflüger, MA Khan, B Kidd, ... bioRxiv, 2022.02. 11.480167, 2022 | 2 | 2022 |
Novel high throughput functional genomics approaches J Gecz, E Nicolas, M Corbett, T Ritchie, I Scheffer, S Berkovic, ... EUROPEAN JOURNAL OF HUMAN GENETICS 32, 82-83, 2024 | | 2024 |
Transactivation of cell lines for functional genomic studies L Jolly, E Nicolas, C Pflueger, R Lister, J Gecz Pathology 55, S20, 2023 | | 2023 |
Transgenerational effects of DNA methylation inhibitor treatment to male mice K Murphy, T Jenkins, C Pflueger, KI Aston, B Cairns, D Carrell Fertility and Sterility 102 (3), e198, 2014 | | 2014 |