| Localised delivery of doxorubicin to prostate cancer cells through a PSMA-targeted hyperbranched polymer theranostic AK Pearce, JD Simpson, NL Fletcher, ZH Houston, AV Fuchs, PJ Russell, ... Biomaterials 141, 330-339, 2017 | 88 | 2017 |
| Effects of surface charge of hyperbranched polymers on cytotoxicity, dynamic cellular uptake and localization, hemotoxicity, and pharmacokinetics in mice L Chen, JD Simpson, AV Fuchs, BE Rolfe, KJ Thurecht Molecular pharmaceutics 14 (12), 4485-4497, 2017 | 71 | 2017 |
| Overcoming instability of antibody‐nanomaterial conjugates: Next generation targeted nanomedicines using bispecific antibodies CB Howard, N Fletcher, ZH Houston, AV Fuchs, NRB Boase, JD Simpson, ... Advanced healthcare materials 5 (16), 2055-2068, 2016 | 68 | 2016 |
| Using peptide aptamer targeted polymers as a model nanomedicine for investigating drug distribution in cancer nanotheranostics Y Zhao, ZH Houston, JD Simpson, L Chen, NL Fletcher, AV Fuchs, ... Molecular Pharmaceutics 14 (10), 3539-3549, 2017 | 57 | 2017 |
| Designed multifunctional polymeric nanomedicines: Long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials NL Fletcher, ZH Houston, JD Simpson, RN Veedu, KJ Thurecht Chemical Communications 54 (82), 11538-11541, 2018 | 41 | 2018 |
| Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery GR Ediriweera, JD Simpson, AV Fuchs, TK Venkatachalam, ... Chemical Science 11 (12), 3268-3280, 2020 | 32 | 2020 |
| Engineered polymeric materials for biological applications: Overcoming challenges of the bio–nano interface JD Simpson, SA Smith, KJ Thurecht, G Such Polymers 11 (9), 1441, 2019 | 32 | 2019 |
| Paired immunoglobulin-like receptor B is an entry receptor for mammalian orthoreovirus P Shang, JD Simpson, GM Taylor, DM Sutherland, OL Welsh, ... Nature communications 14 (1), 2615, 2023 | 17 | 2023 |
| Oral Delivery of Multicompartment Nanomedicines for Colorectal Cancer Therapeutics: Combining Loco‐Regional Delivery with Cell‐Target Specificity DT Akhter, JD Simpson, NL Fletcher, ZH Houston, AV Fuchs, CA Bell, ... Advanced Therapeutics, 2019 | 16 | 2019 |
| Single-molecule analysis of SARS-CoV-2 binding to c-type lectin receptors JD Simpson, A Ray, C Marcon, R dos Santos Natividade, GM Dorrazehi, ... Nano letters 23 (4), 1496-1504, 2023 | 14 | 2023 |
| Role of the redox state of human peroxiredoxin-5 on its TLR4-activating DAMP function MA Poncin, P Van Meerbeeck, JD Simpson, A Clippe, F Tyckaert, ... Antioxidants 10 (12), 1902, 2021 | 14 | 2021 |
| Polymer design and component selection contribute to uptake, distribution & trafficking behaviours of polyethylene glycol hyperbranched polymers in live MDA-MB-468 breast … JD Simpson, GR Ediriweera, CB Howard, NL Fletcher, CA Bell, ... Biomaterials Science 7 (11), 4661-4674, 2019 | 14 | 2019 |
| Enhanced drug delivery to cancer cells through a pH-sensitive polycarbonate platform MC Arno, JD Simpson, LD Blackman, RP Brannigan, KJ Thurecht, ... Biomaterials Science 11 (3), 908-915, 2023 | 10 | 2023 |
| Single-molecule investigation of the binding interface stability of SARS-CoV-2 variants with ACE2 A Ray, TT Minh Tran, R Santos Natividade, RA Moreira, JD Simpson, ... ACS nanoscience Au 4 (2), 136-145, 2024 | 7 | 2024 |
| Deciphering molecular mechanisms stabilizing the reovirus-binding complex R dos Santos Natividade, M Koehler, PSFC Gomes, JD Simpson, ... Proceedings of the National Academy of Sciences 120 (21), e2220741120, 2023 | 7 | 2023 |
| Modulating macrophage clearance of nanoparticles: comparison of small-molecule and biologic drugs as pharmacokinetic modifiers of soft nanomaterials JA Mills, J Humphries, JD Simpson, SE Sonderegger, KJ Thurecht, ... Molecular Pharmaceutics 19 (11), 4080-4097, 2022 | 7 | 2022 |
| Atomic Force Microscopy Applied to Interrogate Nanoscale Cellular Chemistry and Supramolecular Bond Dynamics for Biomedical Applications JD Simpson, A Ray, M Kohler, D Mohammed, D Alsteens Chemical Communications, 2022 | 7 | 2022 |
| Rotavirus Binding to Cell Surface Receptors Directly Recruiting α2 Integrin J Yang, J Park, M Koehler, JD Simpson, D Luque, JM Rodríguez, ... Advanced NanoBiomed Research 1 (12), 2100077, 2021 | 6 | 2021 |
| Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models JD Simpson, PF Monteiro, GR Ediriweera, AR Prior, SE Sonderegger, ... ACS Applied Bio Materials 4 (3), 2675-2685, 2021 | 6 | 2021 |
| Targeted Nanomaterials: Overcoming Instability of Antibody‐Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies (Adv. Healthcare Mater … CB Howard, N Fletcher, ZH Houston, AV Fuchs, NRB Boase, JD Simpson, ... Advanced Healthcare Materials 5 (16), 1994-1994, 2016 | 4 | 2016 |
