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Samuel Kotler
Samuel Kotler
Postdoctoral Fellow at NIH
Verified email at umich.edu
Title
Cited by
Cited by
Year
Differences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease
SA Kotler, P Walsh, JR Brender, A Ramamoorthy
Chemical Society Reviews 43 (19), 6692-6700, 2014
4012014
Two-step mechanism of membrane disruption by Aβ through membrane fragmentation and pore formation
MFM Sciacca, SA Kotler, JR Brender, J Chen, D Lee, A Ramamoorthy
Biophysical journal 103 (4), 702-710, 2012
3912012
Atomic Force Microscopy and MD Simulations Reveal Pore-Like Structures of All-d-Enantiomer of Alzheimer’s β-Amyloid Peptide: Relevance to the Ion Channel …
L Connelly, H Jang, F Teran Arce, R Capone, SA Kotler, ...
The journal of physical chemistry B 116 (5), 1728-1735, 2012
1422012
High-resolution NMR characterization of low abundance oligomers of amyloid-β without purification
SA Kotler, JR Brender, S Vivekanandan, Y Suzuki, K Yamamoto, ...
Scientific reports 5 (1), 11811, 2015
1132015
Lipopolysaccharide from gut microbiota modulates α-synuclein aggregation and alters its biological function
D Bhattacharyya, GM Mohite, J Krishnamoorthy, N Gayen, S Mehra, ...
ACS chemical neuroscience 10 (5), 2229-2236, 2019
832019
Membrane disordering is not sufficient for membrane permeabilization by islet amyloid polypeptide: studies of IAPP (20–29) fragments
JR Brender, DL Heyl, S Samisetti, SA Kotler, JM Osborne, RR Pesaru, ...
Physical Chemistry Chemical Physics 15 (23), 8908-8915, 2013
742013
Detergent-Type Membrane Fragmentation by MSI-78, MSI-367, MSI-594, and MSI-843 Antimicrobial Peptides, and Inhibition by Cholesterol: A Solid-State NMR Study
DK Lee, A Bhunia, SA Kotler, A Ramamoorthy
Biochemistry, 2015
682015
Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR
SA Kotler, V Tugarinov, T Schmidt, A Ceccon, DS Libich, R Ghirlando, ...
Proceedings of the National Academy of Sciences 116 (9), 3562-3571, 2019
672019
Probing structural features of Alzheimer’s amyloid-β pores in bilayers using site-specific amino acid substitutions
R Capone, H Jang, SA Kotler, BL Kagan, R Nussinov, R Lal
Biochemistry 51 (3), 776-785, 2012
592012
All-d-Enantiomer of β-Amyloid Peptide Forms Ion Channels in Lipid Bilayers
R Capone, H Jang, SA Kotler, L Connelly, F Teran Arce, ...
Journal of chemical theory and computation 8 (3), 1143-1152, 2012
562012
Probing transient non-native states in amyloid beta fiber elongation by NMR
JR Brender, A Ghosh, SA Kotler, J Krishnamoorthy, S Bera, V Morris, ...
Chemical Communications 55 (31), 4483-4486, 2019
502019
Interaction of huntingtin exon-1 peptides with lipid-based micellar nanoparticles probed by solution NMR and Q-band pulsed EPR
A Ceccon, T Schmidt, V Tugarinov, SA Kotler, CD Schwieters, GM Clore
Journal of the American Chemical Society 140 (20), 6199-6202, 2018
402018
A blend of two resveratrol derivatives abolishes hIAPP amyloid growth and membrane damage
MFM Sciacca, R Chillemi, S Sciuto, V Greco, C Messineo, SA Kotler, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1793-1802, 2018
392018
Molecular details of a salt bridge and its role in insulin fibrillation by NMR and Raman spectroscopic analysis
BN Ratha, RK Kar, Z Bednarikova, Z Gazova, SA Kotler, S Raha, S De, ...
The Journal of Physical Chemistry B 124 (7), 1125-1136, 2020
102020
Probing the Interaction of Huntingtin Exon‐1 Polypeptides with the Chaperonin Nanomachine GroEL
MA Wälti, SA Kotler, GM Clore
ChemBioChem 22 (11), 1985-1991, 2021
92021
Preparation of Stable Amyloid-β Oligomers Without Perturbative Methods
SA Kotler, A Ramamoorthy
Peptide Self-Assembly: Methods and Protocols, 331-338, 2018
82018
Gangliosides Mediate a Two-Step Mechanism of Membrane Disruption by Beta-Amyloid: Initial Pore Formation Followed by Membrane Fragmentation
SA Kotler, MFM Sciacca, JR Brender, J Chen, K Yamamoto, D Lee, ...
Biophysical Journal 104 (2), 217a, 2013
32013
Probing structural features of amyloid-beta Ion channels in membranes using A-beta mutants
SA Kotler
12011
The role of salt-bridge stability in the initial steps of insulin fibrillation
Z Bednarikova, S De, NC Maiti, A Bhunia, Z Gazova
Book of Contributions, 48, 2020
2020
Probing transient non-native states in amyloid beta fiber elongation by NMR
A Ghosh, SA Kotler, J Krishnamoorthy, S Bera, V Morris, TB Sil, K Garai, ...
Chemical communications 55 (31), 2019
2019
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