Eicke Latz
Eicke Latz
Institute of Innate Immunity, University of Bonn and University of Massachusetts Medical School
Verified email at umassmed.edu - Homepage
Title
Cited by
Cited by
Year
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
P Duewell, H Kono, KJ Rayner, CM Sirois, G Vladimer, FG Bauernfeind, ...
Nature 464 (7293), 1357-1361, 2010
28232010
Neuroinflammation in Alzheimer's disease
MT Heneka, MJ Carson, J El Khoury, GE Landreth, F Brosseron, ...
The Lancet Neurology 14 (4), 388-405, 2015
28022015
IKKε and TBK1 are essential components of the IRF3 signaling pathway
KA Fitzgerald, SM McWhirter, KL Faia, DC Rowe, E Latz, DT Golenbock, ...
Nature immunology 4 (5), 491-496, 2003
26552003
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
V Hornung, F Bauernfeind, A Halle, EO Samstad, H Kono, KL Rock, ...
Nature immunology 9 (8), 847, 2008
25932008
Activation and regulation of the inflammasomes
E Latz, TS Xiao, A Stutz
Nature Reviews Immunology 13 (6), 397-411, 2013
21672013
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
V Hornung, A Ablasser, M Charrel-Dennis, F Bauernfeind, G Horvath, ...
Nature 458 (7237), 514-518, 2009
21282009
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
A Halle, V Hornung, GC Petzold, CR Stewart, BG Monks, T Reinheckel, ...
Nature immunology 9 (8), 857, 2008
19902008
Cutting edge: NF-κB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
FG Bauernfeind, G Horvath, A Stutz, ES Alnemri, K MacDonald, D Speert, ...
The Journal of Immunology 183 (2), 787-791, 2009
18782009
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
E Latz, A Schoenemeyer, A Visintin, KA Fitzgerald, BG Monks, CF Knetter, ...
Nature immunology 5 (2), 190-198, 2004
15172004
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
MT Heneka, MP Kummer, A Stutz, A Delekate, S Schwartz, ...
Nature 493 (7434), 674-678, 2013
14982013
LPS-TLR4 signaling to IRF-3/7 and NF-κB involves the toll adapters TRAM and TRIF
KA Fitzgerald, DC Rowe, BJ Barnes, DR Caffrey, A Visintin, E Latz, ...
The Journal of experimental medicine 198 (7), 1043-1055, 2003
14072003
IFI16 is an innate immune sensor for intracellular DNA
L Unterholzner, SE Keating, M Baran, KA Horan, SB Jensen, S Sharma, ...
Nature immunology 11 (11), 997-1004, 2010
14062010
Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
J Tian, AM Avalos, SY Mao, B Chen, K Senthil, H Wu, P Parroche, ...
Nature immunology 8 (5), 487-496, 2007
13932007
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
J Xue, SV Schmidt, J Sander, A Draffehn, W Krebs, I Quester, D De Nardo, ...
Immunity 40 (2), 274-288, 2014
13622014
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
RC Coll, AAB Robertson, JJ Chae, SC Higgins, R Muņoz-Planillo, ...
Nature medicine 21 (3), 248-255, 2015
12542015
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
VAK Rathinam, Z Jiang, SN Waggoner, S Sharma, LE Cole, L Waggoner, ...
Nature immunology 11 (5), 395, 2010
12112010
Trained immunity: a program of innate immune memory in health and disease
MG Netea, LAB Joosten, E Latz, KHG Mills, G Natoli, HG Stunnenberg, ...
Science 352 (6284), 2016
11992016
Innate immune activation in neurodegenerative disease
MT Heneka, MP Kummer, E Latz
Nature Reviews Immunology 14 (7), 463-477, 2014
9082014
Human lupus autoantibody–DNA complexes activate DCs through cooperation of CD32 and TLR9
TK Means, E Latz, F Hayashi, MR Murali, DT Golenbock, AD Luster
The Journal of clinical investigation 115 (2), 407-417, 2005
8962005
RIG-I-dependent sensing of poly (dA: dT) through the induction of an RNA polymerase III–transcribed RNA intermediate
A Ablasser, F Bauernfeind, G Hartmann, E Latz, KA Fitzgerald, V Hornung
Nature immunology 10 (10), 1065, 2009
8722009
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