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Conor J Kearney
Conor J Kearney
Peter MacCallum Cancer Centre
Verified email at petermac.org
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Cited by
Cited by
Year
Tumor immune evasion arises through loss of TNF sensitivity
CJ Kearney, SJ Vervoort, SJ Hogg, KM Ramsbottom, AJ Freeman, ...
Science immunology 3 (23), eaar3451, 2018
2932018
Fas/CD95-induced chemokines can serve as “find-me” signals for apoptotic cells
SP Cullen, CM Henry, CJ Kearney, SE Logue, M Feoktistova, GA Tynan, ...
Molecular cell 49 (6), 1034-1048, 2013
2372013
Diverse activators of the NLRP3 inflammasome promote IL-1β secretion by triggering necrosis
SP Cullen, CJ Kearney, DM Clancy, SJ Martin
Cell reports 11 (10), 1535-1548, 2015
2352015
An inflammatory perspective on necroptosis
CJ Kearney, SJ Martin
Molecular cell 65 (6), 965-973, 2017
2102017
Inflammatory outcomes of apoptosis, necrosis and necroptosis
P Davidovich, CJ Kearney, SJ Martin
Biological chemistry 395 (10), 1163-1171, 2014
2072014
Necroptosis suppresses inflammation via termination of TNF-or LPS-induced cytokine and chemokine production
CJ Kearney, SP Cullen, GA Tynan, CM Henry, D Clancy, EC Lavelle, ...
Cell Death & Differentiation 22 (8), 1313-1327, 2015
1522015
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
SJ Vervoort, SA Welsh, JR Devlin, E Barbieri, DA Knight, S Offley, ...
Cell 184 (12), 3143-3162. e32, 2021
1152021
RIPK1 can function as an inhibitor rather than an initiator of RIPK3‐dependent necroptosis
CJ Kearney, SP Cullen, D Clancy, SJ Martin
The FEBS journal 281 (21), 4921-4934, 2014
892014
Natural killer cells suppress T cell-associated tumor immune evasion
AJ Freeman, SJ Vervoort, KM Ramsbottom, MJ Kelly, J Michie, L Pijpers, ...
Cell reports 28 (11), 2784-2794. e5, 2019
882019
PTPN 2 phosphatase deletion in T cells promotes anti‐tumour immunity and CAR T‐cell efficacy in solid tumours
F Wiede, KH Lu, X Du, S Liang, K Hochheiser, GT Dodd, PK Goh, ...
The EMBO journal 39 (2), e103637, 2020
872020
PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF
CJ Kearney, N Lalaoui, AJ Freeman, KM Ramsbottom, J Silke, J Oliaro
Cell Death & Differentiation 24 (10), 1705-1716, 2017
762017
Antagonism of IAPs enhances CAR T-cell efficacy
J Michie, PA Beavis, AJ Freeman, SJ Vervoort, KM Ramsbottom, ...
Cancer immunology research 7 (2), 183-192, 2019
732019
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
SJ Hogg, O Motorna, LA Cluse, TM Johanson, HD Coughlan, R Raviram, ...
Molecular cell 81 (10), 2183-2200. e13, 2021
722021
CDK4/6 inhibition promotes antitumor immunity through the induction of T-cell memory
EJ Lelliott, IY Kong, M Zethoven, KM Ramsbottom, LG Martelotto, ...
Cancer discovery 11 (10), 2582-2601, 2021
692021
DOCK8 regulates signal transduction events to control immunity
CJ Kearney, KL Randall, J Oliaro
Cellular & molecular immunology 14 (5), 406-411, 2017
692017
Inhibitor of apoptosis proteins (IAPs) and their antagonists regulate spontaneous and tumor necrosis factor (TNF)-induced proinflammatory cytokine and chemokine production
CJ Kearney, C Sheridan, SP Cullen, GA Tynan, SE Logue, IS Afonina, ...
Journal of Biological Chemistry 288 (7), 4878-4890, 2013
572013
Loss of DNAM-1 ligand expression by acute myeloid leukemia cells renders them resistant to NK cell killing
CJ Kearney, KM Ramsbottom, I Voskoboinik, PK Darcy, J Oliaro
Oncoimmunology 5 (8), e1196308, 2016
542016
MAIT cells regulate NK cell-mediated tumor immunity
EV Petley, HF Koay, MA Henderson, K Sek, KL Todd, SP Keam, J Lai, ...
Nature communications 12 (1), 4746, 2021
512021
SUGAR-seq enables simultaneous detection of glycans, epitopes, and the transcriptome in single cells
CJ Kearney, SJ Vervoort, KM Ramsbottom, I Todorovski, EJ Lelliott, ...
Science advances 7 (8), eabe3610, 2021
512021
The immuno-modulatory effects of inhibitor of apoptosis protein antagonists in cancer immunotherapy
J Michie, CJ Kearney, ED Hawkins, J Silke, J Oliaro
Cells 9 (1), 207, 2020
482020
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