|N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance|
SH Yap, CW Sheen, J Fahey, M Zanin, D Tyssen, VD Lima, B Wynhoven, ...
PLoS medicine 4 (12), e335, 2007
|Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors|
N Sluis-Cremer, G Tachedjian
Virus research 134 (1-2), 147-156, 2008
|Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis|
M Aldunate, D Srbinovski, AC Hearps, CF Latham, PA Ramsland, ...
Frontiers in physiology 6, 164, 2015
|Contraction of the type I IFN locus and unusual constitutive expression of IFN-α in bats|
P Zhou, M Tachedjian, JW Wynne, V Boyd, J Cui, I Smith, C Cowled, ...
Proceedings of the National Academy of Sciences 113 (10), 2696-2701, 2016
|The packaging and maturation of the HIV-1 Pol proteins|
M Hill, G Tachedjian, J Mak
Current HIV research 3 (1), 73-85, 2005
|The role of lactic acid production by probiotic Lactobacillus species in vaginal health|
G Tachedjian, M Aldunate, CS Bradshaw, RA Cone
Research in microbiology 168 (9-10), 782-792, 2017
|Decoding the membrane activity of the cyclotide kalata B1 the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities|
ST Henriques, YH Huang, KJ Rosengren, HG Franquelim, FA Carvalho, ...
Journal of Biological Chemistry 286 (27), 24231-24241, 2011
|SPL7013 Gel (VivaGelŪ) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans|
CF Price, D Tyssen, S Sonza, A Davie, S Evans, GR Lewis, S Xia, ...
PLoS One 6 (9), e24095, 2011
|Structure activity relationship of dendrimer microbicides with dual action antiviral activity|
D Tyssen, SA Henderson, A Johnson, J Sterjovski, K Moore, J La, M Zanin, ...
PloS one 5 (8), e12309, 2010
|An in vivo mutation from leucine to tryptophan at position 210 in human immunodeficiency virus type 1 reverse transcriptase contributes to high-level resistance to 3'-azido-3 …|
DJ Hooker, G Tachedjian, AE Solomon, AD Gurusinghe, S Land, C Birch, ...
Journal of Virology 70 (11), 8010-8018, 1996
|Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase|
G Tachedjian, M Orlova, SG Sarafianos, E Arnold, SP Goff
Proceedings of the National Academy of Sciences 98 (13), 7188-7193, 2001
|Vaginal concentrations of lactic acid potently inactivate HIV|
M Aldunate, D Tyssen, A Johnson, T Zakir, S Sonza, T Moench, R Cone, ...
Journal of Antimicrobial Chemotherapy 68 (9), 2015-2025, 2013
|Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol|
A Figueiredo, KL Moore, J Mak, N Sluis-Cremer, MP de Bethune, ...
PLoS Pathog 2 (11), e119, 2006
|Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions|
ST Henriques, YH Huang, MARB Castanho, LA Bagatolli, S Sonza, ...
Journal of Biological Chemistry 287 (40), 33629-33643, 2012
|Zidovudine resistance is suppressed by mutations conferring resistance of human immunodeficiency virus type 1 to foscarnet.|
G Tachedjian, J Mellors, H Bazmi, C Birch, J Mills
Journal of Virology 70 (10), 7171-7181, 1996
|Maturation of the HIV reverse transcription complex: putting the jigsaw together|
D Warrilow, G Tachedjian, D Harrich
Reviews in medical virology 19 (6), 324-337, 2009
|Altered sensitivity to antiviral drugs of herpes simplex virus isolates from a patient with the acquired immunodeficiency syndrome|
CJ Birch, G Tachedjian, RR Doherty, K Hayes, ID Gust
Journal of Infectious Diseases 162 (3), 731-734, 1990
|Virucidal activity of the dendrimer microbicide SPL7013 against HIV-1|
S Telwatte, K Moore, A Johnson, D Tyssen, J Sterjovski, M Aldunate, ...
Antiviral research 90 (3), 195-199, 2011
|Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV …|
AC Hearps, D Tyssen, D Srbinovski, L Bayigga, DJD Diaz, M Aldunate, ...
Mucosal immunology 10 (6), 1480-1490, 2017
|Antiretroviral compounds: mechanisms underlying failure of HAART to eradicate HIV-1|
M Shehu-Xhilaga, G Tachedjian, SM Crowe, K Kedzierska
Current medicinal chemistry 12 (15), 1705-1719, 2005