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Erik Westein
Erik Westein
Baker IDI Heart and Diabetes Institute
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Cited by
Year
A shear gradient–dependent platelet aggregation mechanism drives thrombus formation
WS Nesbitt, E Westein, FJ Tovar-Lopez, E Tolouei, A Mitchell, J Fu, ...
Nature medicine 15 (6), 665-673, 2009
9392009
Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner
E Westein, AD van der Meer, MJE Kuijpers, JP Frimat, A van den Berg, ...
Proceedings of the National Academy of Sciences 110 (4), 1357-1362, 2013
3032013
Dynamics of platelet thrombus formation
SP Jackson, WS Nesbitt, E Westein
Journal of thrombosis and Haemostasis 7, 17-20, 2009
2872009
Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation
MJ Maxwell, E Westein, WS Nesbitt, S Giuliano, SM Dopheide, ...
Blood 109 (2), 566-576, 2007
2802007
An experimental model to study the in vivo survival of von Willebrand factor: basic aspects and application to the R1205H mutation
PJ Lenting, E Westein, V Terraube, AS Ribba, EG Huizinga, D Meyer, ...
Journal of Biological Chemistry 279 (13), 12102-12109, 2004
2002004
Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes
MJ Kraakman, MKS Lee, A Al-Sharea, D Dragoljevic, TJ Barrett, ...
The Journal of clinical investigation 127 (6), 2133-2147, 2017
1862017
Shear-dependent platelet aggregation: mechanisms and therapeutic opportunities
A Rana, E Westein, B Niego, CE Hagemeyer
Frontiers in cardiovascular medicine 6, 141, 2019
1552019
A microfluidics device to monitor platelet aggregation dynamics in response to strain rate micro-gradients in flowing blood
FJ Tovar-Lopez, G Rosengarten, E Westein, K Khoshmanesh, ...
Lab on a Chip 10 (3), 291-302, 2010
1552010
The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi
M Ghasemzadeh, ZS Kaplan, I Alwis, SM Schoenwaelder, KJ Ashworth, ...
Blood, The Journal of the American Society of Hematology 121 (22), 4555-4566, 2013
1532013
Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth
A Ono, E Westein, S Hsiao, WS Nesbitt, JR Hamilton, SM Schoenwaelder, ...
Blood, The Journal of the American Society of Hematology 112 (1), 90-99, 2008
1522008
Mapping the collagen-binding site in the von Willebrand factor-A3 domain
RA Romijn, E Westein, B Bouma, ME Schiphorst, JJ Sixma, PJ Lenting, ...
Journal of Biological Chemistry 278 (17), 15035-15039, 2003
1462003
Cysteine-mutations in von Willebrand factor associated with increased clearance
CJ van Schooten, P Tjernberg, E Westein, V Terraube, G Castaman, ...
Journal of Thrombosis and Haemostasis 3 (10), 2228-2237, 2005
1212005
Evidence of platelet activation at medically used hypothermia and mechanistic data indicating ADP as a key mediator and therapeutic target
A Straub, S Krajewski, JD Hohmann, E Westein, F Jia, N Bassler, C Selan, ...
Arteriosclerosis, thrombosis, and vascular biology 31 (7), 1607-1616, 2011
1012011
Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated …
X Wang, J Palasubramaniam, Y Gkanatsas, JD Hohmann, E Westein, ...
Circulation research 114 (7), 1083-1093, 2014
902014
Platelet recruitment to the inflamed glomerulus occurs via an αIIbβ3/GPVI-dependent pathway
S Devi, MP Kuligowski, RYQ Kwan, E Westein, SP Jackson, AR Kitching, ...
The American journal of pathology 177 (3), 1131-1142, 2010
802010
Multifunctional thrombin-activatable polymer capsules for specific targeting to activated platelets.
ST Gunawan, K Kempe, T Bonnard, J Cui, K Alt, LS Law, X Wang, ...
Advanced materials (Deerfield Beach, Fla.) 27 (35), 5153-5157, 2015
792015
LDL-receptor–related protein regulates β2-integrin–mediated leukocyte adhesion
PPEM Spijkers, P da Costa Martins, E Westein, CG Gahmberg, ...
Blood 105 (1), 170-177, 2005
782005
Monitoring in vitro thrombus formation with novel microfluidic devices
E Westein, S de Witt, M Lamers, JMEM Cosemans, JWM Heemskerk
Platelets 23 (7), 501-509, 2012
762012
A versatile approach for the site‐specific modification of recombinant antibodies using a combination of enzyme‐mediated bioconjugation and click chemistry
K Alt, BM Paterson, E Westein, SE Rudd, SS Poniger, S Jagdale, ...
Angewandte Chemie international edition 54 (26), 7515-7519, 2015
572015
Survival of von Willebrand factor released following DDAVP in a type 1 von Willebrand disease cohort: influence of glycosylation, proteolysis and gene mutations
CM Millar, AF Riddell, SA Brown, R Starke, I Mackie, DJ Bowen, ...
Thrombosis and haemostasis 99 (11), 916-924, 2008
572008
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