| CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ... Nature communications 8 (1), 14432, 2017 | 472 | 2017 |
| Therapy-induced evolution of human lung cancer revealed by single-cell RNA sequencing A Maynard, CE McCoach, JK Rotow, L Harris, F Haderk, DL Kerr, ... Cell 182 (5), 1232-1251. e22, 2020 | 411 | 2020 |
| The p110δ structure: mechanisms for selectivity and potency of new PI (3) K inhibitors A Berndt, S Miller, O Williams, DD Le, BT Houseman, JI Pacold, F Gorrec, ... Nature chemical biology 6 (2), 117-124, 2010 | 339 | 2010 |
| G-quadruplex ligands exhibit differential G-tetrad selectivity DD Le, M Di Antonio, LKM Chan, S Balasubramanian Chemical Communications 51 (38), 8048-8050, 2015 | 98 | 2015 |
| Comprehensive, high-resolution binding energy landscapes reveal context dependencies of transcription factor binding DD Le, TC Shimko, AK Aditham, AM Keys, SA Longwell, Y Orenstein, ... Proceedings of the National Academy of Sciences 115 (16), E3702-E3711, 2018 | 78 | 2018 |
| Human melanocyte development and melanoma dedifferentiation at single-cell resolution RL Belote, D Le, A Maynard, UE Lang, A Sinclair, BK Lohman, ... Nature Cell Biology 23 (9), 1035-1047, 2021 | 66 | 2021 |
| Docking and linking of fragments to discover jumonji histone demethylase inhibitors M Korczynska, DD Le, N Younger, E Gregori-Puigjané, A Tumber, ... Journal of medicinal chemistry 59 (4), 1580-1598, 2016 | 57 | 2016 |
| Site-specific and regiospecific installation of methylarginine analogues into recombinant histones and insights into effector protein binding DD Le, AT Cortesi, SA Myers, AL Burlingame, DG Fujimori Journal of the American Chemical Society 135 (8), 2879-2882, 2013 | 47 | 2013 |
| Protein and nucleic acid methylating enzymes: mechanisms and regulation DD Le, DG Fujimori Current opinion in chemical biology 16 (5-6), 507-515, 2012 | 31 | 2012 |
| Chloride channels regulate differentiation and barrier functions of the mammalian airway M He, B Wu, W Ye, DD Le, AW Sinclair, V Padovano, Y Chen, KX Li, R Sit, ... Elife 9, e53085, 2020 | 28 | 2020 |
| Association between sexual orientation acceptance and suicidal ideation, substance use, and internalised homophobia amongst the pink carpet Y cohort study of young gay … C Ong, RKJ Tan, D Le, A Tan, A Tyler, C Tan, C Kwok, S Banerjee, ... BMC public health 21 (1), 971, 2021 | 23 | 2021 |
| Social capital and chemsex initiation in young gay, bisexual, and other men who have sex with men: the pink carpet Y cohort study RKJ Tan, CA O’Hara, WL Koh, D Le, A Tan, A Tyler, C Tan, C Kwok, ... Substance abuse treatment, prevention, and policy 16, 1-11, 2021 | 20 | 2021 |
| Experienced homophobia and suicide among young gay, bisexual, transgender, and queer men in Singapore: exploring the mediating role of depression severity, self-esteem, and … RKJ Tan, TQY Low, D Le, A Tan, A Tyler, C Tan, C Kwok, S Banerjee, ... LGBT health 8 (5), 349-358, 2021 | 20 | 2021 |
| Delineating patterns of sexualized substance use and its association with sexual and mental health outcomes among young gay, bisexual and other men who have sex with men in … RKJ Tan, CA O’Hara, WL Koh, D Le, A Tan, A Tyler, C Tan, C Kwok, ... BMC public health 21, 1-11, 2021 | 14 | 2021 |
| Effect of a web drama video series on HIV and other sexually transmitted infection testing among gay, bisexual and queer men: study protocol for a community-based, pragmatic … RKJ Tan, WL Koh, D Le, A Tan, A Tyler, C Tan, S Banerjee, CS Wong, ... BMJ open 10 (4), e033855, 2020 | 10 | 2020 |
| Heterogeneity and targeted therapy-induced adaptations in lung cancer revealed by longitudinal single-cell RNA sequencing A Maynard, CE McCoach, JK Rotow, L Harris, F Haderk, L Kerr, EA Yu, ... BioRxiv, 2019.12. 08.868828, 2019 | 9 | 2019 |
| Systematic discovery of Neoepitope–HLA pairs for neoantigens shared among patients and tumor types HR Gurung, AJ Heidersbach, M Darwish, PPF Chan, J Li, M Beresini, ... Nature Biotechnology, 1-11, 2023 | 7 | 2023 |
| Minority statuses and mental health outcomes among young gay, bisexual and queer men in Singapore RKJ Tan, DWJ Yang, D Le, A Tan, A Tyler, C Tan, C Kwok, S Banerjee, ... Journal of LGBT Youth 20 (1), 198-215, 2023 | 4 | 2023 |
| Effect of a popular web drama video series on HIV and other sexually transmitted infection testing among gay, bisexual, and other men who have sex with men in Singapore … RKJ Tan, WL Koh, D Le, S Banerjee, MTW Chio, RKW Chan, CM Wong, ... Journal of Medical Internet Research 24 (5), e31401, 2022 | 4 | 2022 |
| Comprehensive, high-resolution binding energy landscapes reveal context dependencies of transcription factor binding DD Le, TC Shimko, AK Aditham, AM Keys, Y Orenstein, PM Fordyce BioRxiv, 193904, 2017 | 3 | 2017 |
