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Christopher Slape
Christopher Slape
Senior Research Fellow, University of Queensland
Verified email at uq.edu.au
Title
Cited by
Cited by
Year
NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights
SM Gough, CI Slape, PD Aplan
Blood, The Journal of the American Society of Hematology 118 (24), 6247-6257, 2011
3222011
NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia
YW Lin, C Slape, Z Zhang, PD Aplan
Blood 106 (1), 287-295, 2005
2492005
NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia
YW Lin, C Slape, Z Zhang, PD Aplan
Blood 106 (1), 287-295, 2005
2492005
The role of NUP98 gene fusions in hematologic malignancy
C Slape, PD Aplan
Leukemia & lymphoma 45 (7), 1341-1350, 2004
1262004
Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model
S Greenblatt, L Li, C Slape, B Nguyen, R Novak, A Duffield, D Huso, ...
Blood, The Journal of the American Society of Hematology 119 (12), 2883-2894, 2012
942012
Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation
C Slape, H Hartung, YW Lin, J Bies, L Wolff, PD Aplan
Cancer research 67 (11), 5148-5155, 2007
822007
Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl
C Slape, LY Liu, S Beachy, PD Aplan
Blood, The Journal of the American Society of Hematology 112 (5), 2017-2019, 2008
772008
EphA3 biology and cancer
PW Janes, CI Slape, RH Farnsworth, L Atapattu, AM Scott, ME Vail
Growth factors 32 (6), 176-189, 2014
712014
Transplantation of a myelodysplastic syndrome by a long-term repopulating hematopoietic cell
YJ Chung, CW Choi, C Slape, T Fry, PD Aplan
Proceedings of the National Academy of Sciences 105 (37), 14088-14093, 2008
472008
Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome
CI Slape, J Saw, JBM Jowett, PD Aplan, A Strasser, SM Jane, DJ Curtis
Blood, The Journal of the American Society of Hematology 120 (12), 2475-2483, 2012
452012
NUP98-HOX translocations lead to myelodysplastic syndrome in mice and men
C Slape, YW Lin, H Hartung, Z Zhang, L Wolff, PD Aplan
Journal of the National Cancer Institute Monographs 2008 (39), 64-68, 2008
402008
OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1
YW Lin, R Deveney, M Barbara, NN Iscove, SD Nimer, C Slape, PD Aplan
Cancer Research 65 (16), 7151-7158, 2005
352005
Gene expression profiling and candidate gene resequencing identifies pathways and mutations important for malignant transformation caused by leukemogenic fusion genes
RL Novak, DP Harper, D Caudell, C Slape, SH Beachy, PD Aplan
Experimental hematology 40 (12), 1016-1027, 2012
322012
A NUP98-HOXD13 fusion gene impairs differentiation of B and T lymphocytes and leads to expansion of thymocytes with partial TCRB gene rearrangement
CW Choi, YJ Chung, C Slape, PD Aplan
The Journal of Immunology 183 (10), 6227-6235, 2009
302009
Impaired differentiation and apoptosis of hematopoietic precursors in a mouse model of myelodysplastic syndrome
CW Choi, YJ Chung, C Slape, PD Aplan
Haematologica 93 (9), 1394, 2008
302008
Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice
D Caudell, DP Harper, RL Novak, RM Pierce, C Slape, L Wolff, PD Aplan
Blood, The Journal of the American Society of Hematology 115 (6), 1194-1203, 2010
282010
PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia
AA Guirguis, CI Slape, LM Failla, J Saw, CS Tremblay, DR Powell, ...
Cell Death & Differentiation 23 (6), 1049-1059, 2016
172016
The fusion partner specifies the oncogenic potential of NUP98 fusion proteins
J Saw, DJ Curtis, DJ Hussey, A Dobrovic, PD Aplan, CI Slape
Leukemia research 37 (12), 1668-1673, 2013
172013
Mouse embryonic stem cells that express a NUP98–HOXD13 fusion protein are impaired in their ability to differentiate and can be complemented by BCR-ABL
C Slape, YJ Chung, PD Soloway, L Tessarollo, PD Aplan
Leukemia 21 (6), 1239-1248, 2007
152007
The NUP98-HOXD13 fusion oncogene induces thymocyte self-renewal via Lmo2/Lyl1
BJ Shields, CI Slape, N Vo, JT Jackson, A Pliego-Zamora, H Ranasinghe, ...
Leukemia 33 (8), 1868-1880, 2019
132019
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