Richard Bickerton
Richard Bickerton
Exscientia, University of Dundee
Verified email at exscientia.co.uk - Homepage
Title
Cited by
Cited by
Year
Quantifying the chemical beauty of drugs
GR Bickerton, GV Paolini, J Besnard, S Muresan, AL Hopkins
Nature chemistry 4 (2), 90-98, 2012
5772012
Automated design of ligands to polypharmacological profiles
J Besnard, GF Ruda, V Setola, K Abecassis, RM Rodriguiz, XP Huang, ...
Nature 492 (7428), 215-220, 2012
5372012
Atomic interactions and profile of small molecules disrupting protein–protein interfaces: the TIMBAL database
AP Higueruelo, A Schreyer, GRJ Bickerton, WR Pitt, CR Groom, ...
Chemical biology & drug design 74 (5), 457-467, 2009
1642009
A structural bioinformatics approach to the analysis of nonsynonymous single nucleotide polymorphisms (nsSNPs) and their relation to disease
CL Worth, GRJ Bickerton, A Schreyer, JR Forman, TMK Cheng, S Lee, ...
Journal of bioinformatics and computational biology 5 (06), 1297-1318, 2007
732007
Comprehensive, atomic-level characterization of structurally characterized protein-protein interactions: the PICCOLO database
GR Bickerton, AP Higueruelo, TL Blundell
BMC bioinformatics 12 (1), 313, 2011
612011
Structural bioinformatics mutation analysis reveals genotype–phenotype correlations in von Hippel‐Lindau disease and suggests molecular mechanisms of tumorigenesis
JR Forman, CL Worth, GRJ Bickerton, TG Eisen, TL Blundell
Proteins: Structure, Function, and Bioinformatics 77 (1), 84-96, 2009
582009
Structural and functional restraints in the evolution of protein families and superfamilies
S Gong, CL Worth, GRJ Bickerton, S Lee, D Tanramluk, TL Blundell
Biochemical Society Transactions 37 (4), 727-733, 2009
402009
An ontology for description of drug discovery investigations
D Qi, RD King, AL Hopkins, GRJ Bickerton, LN Soldatova
Journal of integrative bioinformatics 7 (3), 156-168, 2010
352010
Meta-QSAR: a large-scale application of meta-learning to drug design and discovery
I Olier, N Sadawi, GR Bickerton, J Vanschoren, C Grosan, L Soldatova, ...
Machine Learning 107 (1), 285-311, 2018
312018
Rapid Analysis of Pharmacology for Infectious Diseases
A L Hopkins, G Richard Bickerton, I M Carruthers, S K Boyer, H Rubin, ...
Current topics in medicinal chemistry 11 (10), 1292-1300, 2011
242011
What can we learn from the evolution of protein-ligand interactions to aid the design of new therapeutics?
AP Higueruelo, A Schreyer, GRJ Bickerton, TL Blundell, WR Pitt
PloS one 7 (12), e51742, 2012
212012
Drug discovery: Know your chemical space
AL Hopkins, GR Bickerton
Nature Chemical Biology 6 (7), 482, 2010
212010
Structural interactomics: informatics approaches to aid the interpretation of genetic variation and the development of novel therapeutics
S Lee, A Brown, WR Pitt, AP Higueruelo, S Gong, GR Bickerton, ...
Molecular Biosystems 5 (12), 1456-1472, 2009
102009
Molecular characterization and evolutionary plasticity of protein-protein interfaces
GRJ Bickerton
University of Cambridge, 2011
72011
An Ontology for Description of Drug Discovery Investigations
GRJ Bickerton, AL Hopkins, RD King, D Qi, LN Soldatova
http://journal. imbio. de/article. php? aid= 126, 0
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Articles 1–15