Richard Bickerton
Richard Bickerton
Exscientia, University of Dundee
Verified email at - Homepage
Cited by
Cited by
Automated design of ligands to polypharmacological profiles
J Besnard, GF Ruda, V Setola, K Abecassis, RM Rodriguiz, XP Huang, ...
Nature 492 (7428), 215-220, 2012
Quantifying the chemical beauty of drugs
GR Bickerton, GV Paolini, J Besnard, S Muresan, AL Hopkins
Nature chemistry 4 (2), 90, 2012
Atomic interactions and profile of small molecules disrupting protein–protein interfaces: the TIMBAL database
AP Higueruelo, A Schreyer, GRJ Bickerton, WR Pitt, CR Groom, ...
Chemical biology & drug design 74 (5), 457-467, 2009
A structural bioinformatics approach to the analysis of nonsynonymous single nucleotide polymorphisms (nsSNPs) and their relation to disease
CL Worth, GRJ Bickerton, A Schreyer, JR Forman, TMK Cheng, S Lee, ...
Journal of bioinformatics and computational biology 5 (06), 1297-1318, 2007
Structural bioinformatics mutation analysis reveals genotype–phenotype correlations in von Hippel‐Lindau disease and suggests molecular mechanisms of tumorigenesis
JR Forman, CL Worth, GRJ Bickerton, TG Eisen, TL Blundell
Proteins: Structure, Function, and Bioinformatics 77 (1), 84-96, 2009
Comprehensive, atomic-level characterization of structurally characterized protein-protein interactions: the PICCOLO database
GR Bickerton, AP Higueruelo, TL Blundell
BMC bioinformatics 12 (1), 313, 2011
Structural and functional restraints in the evolution of protein families and superfamilies
S Gong, CL Worth, GRJ Bickerton, S Lee, D Tanramluk, TL Blundell
Biochemical Society Transactions 37 (4), 727-733, 2009
An ontology for description of drug discovery investigations
D Qi, RD King, AL Hopkins, GRJ Bickerton, LN Soldatova
Journal of integrative bioinformatics 7 (3), 156-168, 2010
Rapid Analysis of Pharmacology for Infectious Diseases
A L Hopkins, G Richard Bickerton, I M Carruthers, S K Boyer, H Rubin, ...
Current topics in medicinal chemistry 11 (10), 1292-1300, 2011
What can we learn from the evolution of protein-ligand interactions to aid the design of new therapeutics?
AP Higueruelo, A Schreyer, GRJ Bickerton, TL Blundell, WR Pitt
PloS one 7 (12), 2012
Meta-QSAR: a large-scale application of meta-learning to drug design and discovery
I Olier, N Sadawi, GR Bickerton, J Vanschoren, C Grosan, L Soldatova, ...
Machine Learning 107 (1), 285-311, 2018
Know your chemical space
AL Hopkins, GR Bickerton
Nature chemical biology 6 (7), 482-483, 2010
Structural interactomics: informatics approaches to aid the interpretation of genetic variation and the development of novel therapeutics
S Lee, A Brown, WR Pitt, AP Higueruelo, S Gong, GR Bickerton, ...
Molecular Biosystems 5 (12), 1456-1472, 2009
Molecular characterization and evolutionary plasticity of protein-protein interfaces
GRJ Bickerton
University of Cambridge, 2011
An Ontology for Description of Drug Discovery Investigations
GRJ Bickerton, AL Hopkins, RD King, D Qi, LN Soldatova
http://journal. imbio. de/article. php? aid= 126, 0
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