| Selective vulnerability of cancer cells by inhibition of Ca2+ transfer from endoplasmic reticulum to mitochondria C Cárdenas, M Müller, A McNeal, A Lovy, F Jaňa, G Bustos, F Urra, ... Cell reports 14 (10), 2313-2324, 2016 | 262 | 2016 |
| The mitochondrial complex (I) ty of cancer FA Urra, F Muñoz, A Lovy, C Cárdenas Frontiers in oncology 7, 118, 2017 | 147 | 2017 |
| FR58P1a; a new uncoupler of OXPHOS that inhibits migration in triple-negative breast cancer cells via Sirt1/AMPK/β1-integrin pathway FA Urra, F Muñoz, M Córdova-Delgado, MP Ramírez, B Peña-Ahumada, ... Scientific reports 8 (1), 13190, 2018 | 61 | 2018 |
| Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum–to–mitochondria Ca2+ transfer for survival C Cardenas, A Lovy, E Silva-Pavez, F Urra, C Mizzoni, ... Science signaling 13 (640), eaay1212, 2020 | 60 | 2020 |
| Antiproliferative activity and chemical composition of the venom from the Amazonian toad Rhinella marina (Anura: Bufonidae) G Schmeda-Hirschmann, C Quispe, GV Arana, C Theoduloz, FA Urra, ... Toxicon 121, 119-129, 2016 | 57 | 2016 |
| Regulation of mitochondrial function as a promising target in platelet activation-related diseases E Fuentes, R Araya-Maturana, FA Urra Free Radical Biology and Medicine 136, 172-182, 2019 | 55 | 2019 |
| Mitochondria: A promising target for anticancer alkaloids F A Urra, M Córdova-Delgado, H Pessoa-Mahana, O Ramírez-Rodríguez, ... Current Topics in Medicinal Chemistry 13 (17), 2171-2183, 2013 | 41 | 2013 |
| Determinants of anti-cancer effect of mitochondrial electron transport chain inhibitors: bioenergetic profile and metabolic flexibility of cancer cells F A. Urra, B Weiss-Lopez, R Araya-Maturana Current Pharmaceutical Design 22 (39), 5998-6008, 2016 | 40 | 2016 |
| Small structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of tumoral oxidative phosphorylation FA Urra, M Córdova-Delgado, M Lapier, A Orellana-Manzano, ... Toxicology and applied pharmacology 291, 46-57, 2016 | 38 | 2016 |
| An ortho-carbonyl substituted hydroquinone derivative is an anticancer agent that acts by inhibiting mitochondrial bioenergetics and by inducing G2/M-phase arrest in mammary … FA Urra, M Martínez-Cifuentes, M Pavani, M Lapier, F Jaña-Prado, ... Toxicology and applied pharmacology 267 (3), 218-227, 2013 | 37 | 2013 |
| Targeting metastasis with snake toxins: molecular mechanisms FA Urra, R Araya-Maturana Toxins 9 (12), 390, 2017 | 35 | 2017 |
| Complex Mitochondrial Dysfunction Induced by TPP+-Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast … S Fuentes-Retamal, C Sandoval-Acuña, L Peredo-Silva, ... Cells 9 (2), 407, 2020 | 32 | 2020 |
| The Paraguayan Rhinella toad venom: Implications in the traditional medicine and proliferation of breast cancer cells G Schmeda-Hirschmann, CV Gomez, AR de Arias, A Burgos-Edwards, ... Journal of ethnopharmacology 199, 106-118, 2017 | 31 | 2017 |
| Putting the brakes on tumorigenesis with snake venom toxins: New molecular insights for cancer drug discovery FA Urra, R Araya-Maturana Seminars in Cancer Biology 80, 195-204, 2022 | 30 | 2022 |
| Extracellular matrix signals as drivers of mitochondrial bioenergetics and metabolic plasticity of cancer cells during metastasis FA Urra, S Fuentes-Retamal, C Palominos, YA Rodríguez-Lucart, ... Frontiers in cell and developmental biology 9, 751301, 2021 | 30 | 2021 |
| Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6 D Méndez, FA Urra, JP Millas-Vargas, M Alarcón, J Rodríguez-Lavado, ... European Journal of Medicinal Chemistry 192, 112187, 2020 | 30 | 2020 |
| The true identity of the new world iguanid lizard Liolaemus chillanensis Müller and Hellmich 1932 (Iguania: Liolaemidae) and description of a new species in the Liolaemus … J Troncoso-Palacios, D Esquerré, FA Urra, HA Díaz, C Castro-Pastene, ... Zoological Studies 57, 2018 | 25 | 2018 |
| Complex I and II are required for normal mitochondrial Ca2+ homeostasis F Jaña, G Bustos, J Rivas, P Cruz, F Urra, C Basualto-Alarcón, E Sagredo, ... Mitochondrion 49, 73-82, 2019 | 24 | 2019 |
| An acylhydroquinone derivative produces OXPHOS uncoupling and sensitization to BH3 mimetic ABT-199 (Venetoclax) in human promyelocytic leukemia cells V Donoso-Bustamante, EA Borrego, Y Schiaffino-Bustamante, ... Bioorganic Chemistry 100, 103935, 2020 | 20 | 2020 |
| The role of cholesterol and mitochondrial bioenergetics in activation of the inflammasome in IBD J Astorga, N Gasaly, K Dubois-Camacho, M De la Fuente, G Landskron, ... Frontiers in immunology 13, 1028953, 2022 | 19 | 2022 |
