Phase separation of a PKA regulatory subunit controls cAMP compartmentation and oncogenic signaling JZ Zhang, TW Lu, LM Stolerman, B Tenner, JR Yang, JF Zhang, M Falcke, ... Cell 182 (6), 1531-1544. e15, 2020 | 199 | 2020 |
Single-fluorophore biosensors for sensitive and multiplexed detection of signalling activities S Mehta, Y Zhang, RH Roth, J Zhang, A Mo, B Tenner, RL Huganir, ... Nature cell biology 20 (10), 1215-1225, 2018 | 137 | 2018 |
An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice JF Zhang, B Liu, I Hong, A Mo, RH Roth, B Tenner, W Lin, JZ Zhang, ... Nature chemical biology 17 (1), 39-46, 2021 | 59 | 2021 |
Signaling diversity enabled by Rap1-regulated plasma membrane ERK with distinct temporal dynamics J Keyes, A Ganesan, O Molinar-Inglis, A Hamidzadeh, J Zhang, M Ling, ... Elife 9, e57410, 2020 | 36 | 2020 |
Sirt3 mediates the inhibitory effect of adjudin on astrocyte activation and glial scar formation following ischemic stroke X Yang, K Geng, J Zhang, Y Zhang, J Shao, W Xia Frontiers in Pharmacology 8, 943, 2017 | 33 | 2017 |
Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter DL Schmitt, SD Curtis, AC Lyons, J Zhang, M Chen, CY He, S Mehta, ... Nature communications 13 (1), 3856, 2022 | 25 | 2022 |
Sirt3 deficiency impairs neurovascular recovery in ischemic stroke X Yang, KY Geng, YS Zhang, JF Zhang, K Yang, JX Shao, WL Xia CNS neuroscience & therapeutics 24 (9), 775-783, 2018 | 23 | 2018 |
Signaling microdomains in the spotlight: visualizing compartmentalized signaling using genetically encoded fluorescent biosensors JF Zhang, S Mehta, J Zhang Annual review of pharmacology and toxicology 61, 587-608, 2021 | 19 | 2021 |
Endosome positioning coordinates spatially selective GPCR signaling BKA Willette, JF Zhang, J Zhang, NG Tsvetanova Nature Chemical Biology, 1-11, 2023 | 11 | 2023 |
Protocol for reading and imaging live-cell PKA activity using ExRai-AKAR2 J Zhang, S Mehta, J Zhang STAR protocols 3 (1), 101071, 2022 | 2 | 2022 |
PKA RIα phase separation drives cAMP compartmentation and suppresses tumorigenic signaling JZ Zhang, TW Lu, B Tenner, J Yang, JF Zhang, S Taylor, S Mehta, ... The FASEB Journal 34 (S1), 1-1, 2020 | 2 | 2020 |
Illuminating Spatiotemporal Regulation of AMPK with a Genetically Encoded Excitation‐Ratiometric Biosensor for AMPK DL Schmitt, J Zhang, M Chen, A Leung, CY He, SD Curtis, S Mehta, ... The FASEB Journal 34 (S1), 1-1, 2020 | 1 | 2020 |
An Ultrasensitive PKA Biosensor for Multi-modal Kinase Activity Detection and High-Resolution Imaging in Awake Mice B Liu, JF Zhang, I Hong, A Mo, R Roth, B Tenner, W Lin, J Zhang, ... FASEB JOURNAL 35, 2021 | | 2021 |
An Ultrasensitive Fluorescent Biosensor for Multi‐modal Kinase Activity Detection and High‐resolution Imaging in Awake Mice S Mehta, JF Zhang, B Liu, I Hong, B Tenner, W Lin, RL Huganir, J Zhang The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |