|Acidity generated by the tumor microenvironment drives local invasion|
V Estrella, T Chen, M Lloyd, J Wojtkowiak, HH Cornnell, ...
Cancer research 73 (5), 1524-1535, 2013
|Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors|
VA Adalsteinsson, G Ha, SS Freeman, AD Choudhury, DG Stover, ...
Nature communications 8 (1), 1-13, 2017
|12-Chemokine gene signature identifies lymph node-like structures in melanoma: potential for patient selection for immunotherapy?|
JL Messina, DA Fenstermacher, S Eschrich, X Qu, AE Berglund, MC Lloyd, ...
Scientific reports 2, 765, 2012
|Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments|
JW Wojtkowiak, JM Rothberg, V Kumar, KJ Schramm, E Haller, ...
Cancer research 72 (16), 3938-3947, 2012
|Multiscale modelling of vascular tumour growth in 3D: the roles of domain size and boundary conditions|
H Perfahl, HM Byrne, T Chen, V Estrella, T Alarcón, A Lapin, RA Gatenby, ...
PloS one 6 (4), e14790, 2011
|Darwinian dynamics of intratumoral heterogeneity: not solely random mutations but also variable environmental selection forces|
MC Lloyd, JJ Cunningham, MM Bui, RJ Gillies, JS Brown, RA Gatenby
Cancer research 76 (11), 3136-3144, 2016
|A physical sciences network characterization of non-tumorigenic and metastatic cells|
TPSOC Network, DB Agus, JF Alexander, W Arap, S Ashili, JE Aslan, ...
Scientific reports 3, 1449, 2013
|Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane|
M Damaghi, NK Tafreshi, MC Lloyd, R Sprung, V Estrella, JW Wojtkowiak, ...
Nature communications 6 (1), 1-13, 2015
|Systemic buffers inhibit carcinogenesis in TRAMP mice|
A Ibrahim-Hashim, HH Cornnell, D Abrahams, M Lloyd, M Bui, RJ Gillies, ...
The Journal of urology 188 (2), 624-631, 2012
|ARRB1-mediated regulation of E2F target genes in nicotine-induced growth of lung tumors|
P Dasgupta, W Rizwani, S Pillai, R Davis, S Banerjee, K Hug, M Lloyd, ...
Journal of the National Cancer Institute 103 (4), 317-333, 2011
|Defining cancer subpopulations by adaptive strategies rather than molecular properties provides novel insights into intratumoral evolution|
A Ibrahim-Hashim, M Robertson-Tessi, PM Enriquez-Navas, M Damaghi, ...
Cancer research 77 (9), 2242-2254, 2017
|Reduction of metastasis using a non-volatile buffer|
AI Hashim, HH Cornnell, MLC Ribeiro, D Abrahams, J Cunningham, ...
Clinical & experimental metastasis 28 (8), 841-849, 2011
|Noninvasive detection of breast cancer lymph node metastasis using carbonic anhydrases IX and XII targeted imaging probes|
NK Tafreshi, MM Bui, K Bishop, MC Lloyd, SA Enkemann, AS Lopez, ...
Clinical Cancer Research 18 (1), 207-219, 2012
|Using image analysis as a tool for assessment of prognostic and predictive biomarkers for breast cancer: How reliable is it?|
MC Lloyd, P Allam-Nandyala, CN Purohit, N Burke, D Coppola, MM Bui
Journal of pathology informatics 1, 2010
|Carbonic anhydrase IX as an imaging and therapeutic target for tumors and metastases|
NK Tafreshi, MC Lloyd, MM Bui, RJ Gillies, DL Morse
Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial …, 2014
|MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion|
J Gao, MJ McConnell, B Yu, J Li, JM Balko, EP Black, JO Johnson, ...
International journal of oncology 35 (2), 337-345, 2009
|Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance|
D Verduzco, M Lloyd, L Xu, A Ibrahim-Hashim, Y Balagurunathan, ...
PloS one 10 (3), e0120958, 2015
|Autophagy induced by conventional chemotherapy mediates tumor cell sensitivity to immunotherapy|
R Ramakrishnan, C Huang, HI Cho, M Lloyd, J Johnson, X Ren, S Altiok, ...
Cancer research 72 (21), 5483-5493, 2012
|Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302|
JW Wojtkowiak, HC Cornnell, S Matsumoto, K Saito, Y Takakusagi, ...
Cancer & metabolism 3 (1), 1-13, 2015
|A mammaglobin-A targeting agent for noninvasive detection of breast cancer metastasis in lymph nodes|
NK Tafreshi, SA Enkemann, MM Bui, MC Lloyd, D Abrahams, AS Huynh, ...
Cancer research 71 (3), 1050-1059, 2011