| RNA-guided human genome engineering via Cas9 P Mali, L Yang, KM Esvelt, J Aach, M Guell, JE DiCarlo, JE Norville, ... Science 339 (6121), 823-826, 2013 | 15172 | 2013 |
| CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering P Mali, J Aach, PB Stranges, KM Esvelt, M Moosburner, S Kosuri, L Yang, ... Nature biotechnology 31 (9), 833-838, 2013 | 1657 | 2013 |
| Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies G Wang, ML McCain, L Yang, A He, FS Pasqualini, A Agarwal, H Yuan, ... Nature medicine 20 (6), 616-623, 2014 | 608 | 2014 |
| Genome-wide inactivation of porcine endogenous retroviruses (PERVs) L Yang, M Güell, D Niu, H George, E Lesha, D Grishin, J Aach, E Shrock, ... Science 350 (6264), 1101-1104, 2015 | 470 | 2015 |
| Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9 D Niu, HJ Wei, L Lin, H George, T Wang, IH Lee, HY Zhao, Y Wang, Y Kan, ... Science 357 (6357), 1303-1307, 2017 | 396 | 2017 |
| Optimization of scarless human stem cell genome editing L Yang, M Guell, S Byrne, JL Yang, A De Los Angeles, P Mali, J Aach, ... Nucleic acids research 41 (19), 9049-9061, 2013 | 376 | 2013 |
| Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy JT Hinson, A Chopra, N Nafissi, WJ Polacheck, CC Benson, S Swist, ... Science 349 (6251), 982-986, 2015 | 359 | 2015 |
| Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers AW Briggs, X Rios, R Chari, L Yang, F Zhang, P Mali, GM Church Nucleic acids research 40 (15), e117-e117, 2012 | 239 | 2012 |
| Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers AW Briggs, X Rios, R Chari, L Yang, F Zhang, P Mali, GM Church Nucleic acids research 40 (15), e117-e117, 2012 | 239 | 2012 |
| A public resource facilitating clinical use of genomes MP Ball, JV Thakuria, AW Zaranek, T Clegg, AM Rosenbaum, X Wu, ... Proceedings of the National Academy of Sciences 109 (30), 11920-11927, 2012 | 185 | 2012 |
| The genome project-write JD Boeke, G Church, A Hessel, NJ Kelley, A Arkin, Y Cai, R Carlson, ... Science 353 (6295), 126-127, 2016 | 179 | 2016 |
| RNA-Guided Human Genome Engineering GM Church, L Yang US Patent App. 14/318,933, 2014 | 164* | 2014 |
| RNA-guided human genome engineering GM Church, L Yang US Patent 9,023,649, 2015 | 144 | 2015 |
| RNA-guided human genome engineering GM Church, L Yang US Patent 9,260,723, 2016 | 136 | 2016 |
| Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells L Yang, D Grishin, G Wang, J Aach, CZ Zhang, R Chari, J Homsy, X Cai, ... Nature communications 5 (1), 1-6, 2014 | 121 | 2014 |
| b RNA-guided human genome engineering via Cas9 P Mali, L Yang, KM Esvelt, J Aach, M Guell, JE DiCarlo, JE Norville, ... Science 339 (6121), 823-826, 2013 | 119 | 2013 |
| RNA-guided human genome engineering GM Church, L Yang US Patent 9,260,723, 2016 | 111 | 2016 |
| Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA) M Güell, L Yang, GM Church Bioinformatics 30 (20), 2968-2970, 2014 | 109 | 2014 |
| RNA-guided human genome engineering GM Church, L Yang US Patent 10,717,990, 2020 | 90 | 2020 |
| RNA-Guided Human Genome Engineering GM Church, P Mali, L Yang US Patent App. 14/681,510, 2015 | 75 | 2015 |
