| Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes Y Huang, E Greene, T Murray Stewart, AC Goodwin, SB Baylin, ... Proceedings of the National Academy of Sciences 104 (19), 8023-8028, 2007 | 368 | 2007 |
| Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes Y Huang, TM Stewart, Y Wu, SB Baylin, LJ Marton, B Perkins, RJ Jones, ... Clinical Cancer Research 15 (23), 7217-7228, 2009 | 250 | 2009 |
| Nuclear factor-κB/IκB signaling pathway may contribute to the mediation of paclitaxel-induced apoptosis in solid tumor cells Y Huang, KR Johnson, JS Norris, W Fan Cancer research 60 (16), 4426-4432, 2000 | 210 | 2000 |
| Epigenetics in breast cancer: what's new? Y Huang, S Nayak, R Jankowitz, NE Davidson, S Oesterreich Breast Cancer Research 13, 225, 2011 | 181 | 2011 |
| Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade Y Qin, SN Vasilatos, L Chen, H Wu, Z Cao, Y Fu, M Huang, AM Vlad, B Lu, ... Oncogene 38 (3), 390-405, 2019 | 171 | 2019 |
| Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells Y Huang, SN Vasilatos, L Boric, PG Shaw, NE Davidson Breast cancer research and treatment 131, 777-789, 2012 | 164 | 2012 |
| Spermine oxidase SMO (PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines A Pledgie, Y Huang, A Hacker, Z Zhang, PM Woster, NE Davidson, ... Journal of Biological Chemistry 280 (48), 39843-39851, 2005 | 156 | 2005 |
| Super-Resolution Imaging of Higher-Order Chromatin Structures at Different Epigenomic States in Single Mammalian Cells J Xu, H Ma, J Jin, S Uttam, R Fu, Y Huang, Y Liu Cell Reports 24 (4), 873-882, 2018 | 150 | 2018 |
| Molecular mechanisms of polyamine analogs in cancer cells Y Huang, A Pledgie, RA Casero Jr, NE Davidson Anti-cancer drugs 16 (3), 229-241, 2005 | 146 | 2005 |
| Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells SN Vasilatos, TA Katz, S Oesterreich, Y Wan, NE Davidson, Y Huang Carcinogenesis 34 (6), 1196-1207, 2013 | 134 | 2013 |
| The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway K Jin, X Kong, T Shah, MF Penet, F Wildes, DC Sgroi, XJ Ma, Y Huang, ... Proceedings of the National Academy of Sciences 109 (8), 2736-2741, 2012 | 133 | 2012 |
| Immunotherapy efficacy on mismatch repair-deficient colorectal cancer: from bench to bedside DY Lizardo, C Kuang, S Hao, J Yu, Y Huang, L Zhang Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1874 (2), 188447, 2020 | 125 | 2020 |
| Estrogen receptor α mediates breast cancer cell resistance to paclitaxel through inhibition of apoptotic cell death M Sui, Y Huang, BH Park, NE Davidson, W Fan Cancer research 67 (11), 5337-5344, 2007 | 119 | 2007 |
| Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells Q Zhu, Y Huang, LJ Marton, PM Woster, NE Davidson, RA Casero Amino acids 42, 887-898, 2012 | 106 | 2012 |
| Functional interaction of histone deacetylase 5 (HDAC5) and lysine-specific demethylase 1 (LSD1) promotes breast cancer progression C Cao, SN Vasilatos, R Bhargava, JL Fine, S Oesterreich, NE Davidson, ... Oncogene 36, 133–145, 2016 | 105 | 2016 |
| A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells Y Huang, ER Hager, DL Phillips, VR Dunn, A Hacker, B Frydman, JA Kink, ... Clinical cancer research 9 (7), 2769-2777, 2003 | 104 | 2003 |
| Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells TA Katz, SN Vasilatos, E Harrington, S Oesterreich, NE Davidson, ... Breast cancer research and treatment 146 (1), 99-108, 2014 | 98 | 2014 |
| IκB kinase activation is involved in regulation of paclitaxel-induced apoptosis in human tumor cell lines Y Huang, W Fan Molecular pharmacology 61 (1), 105-113, 2002 | 97 | 2002 |
| Regulation of Vinca alkaloid-induced apoptosis by NF-κB/IκB pathway in human tumor cells Y Huang, Y Fang, J Wu, JM Dziadyk, X Zhu, M Sui, W Fan Molecular cancer therapeutics 3 (3), 271-277, 2004 | 94 | 2004 |
| Withaferin a suppresses estrogen receptor‐α expression in human breast cancer cells ER Hahm, J Lee, Y Huang, SV Singh Molecular carcinogenesis 50 (8), 614-624, 2011 | 87 | 2011 |
