Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 8588 | 2021 |
Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization TJ Sargeant, B Lloyd-Lewis, HK Resemann, A Ramos-Montoya, ... Nature cell biology 16 (11), 1057-1068, 2014 | 132 | 2014 |
Endo‐lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease? LS Whyte, AA Lau, KM Hemsley, JJ Hopwood, TJ Sargeant Journal of neurochemistry 140 (5), 703-717, 2017 | 106 | 2017 |
Retromer has a selective function in cargo sorting via endosome transport carriers. Y Cui, JM Carosi, Z Yang, N Ariotti, MC Kerr, RG Parton, TJ Sargeant, ... Journal of Cell Biology, 2019 | 85 | 2019 |
Opioidergic regulation of astroglial/neuronal proliferation: where are we now? TJ Sargeant, JH Miller, DJ Day Journal of neurochemistry 107 (4), 883-897, 2008 | 77 | 2008 |
Guidelines for the use and interpretation of assays for monitoring autophagy 1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... Autophagy 17 (1), 1, 2021 | 52 | 2021 |
Adeno-associated virus-mediated expression of β-hexosaminidase prevents neuronal loss in the Sandhoff mouse brain TJ Sargeant, S Wang, J Bradley, NJC Smith, AA Raha, R McNair, ... Human molecular genetics 20 (22), 4371-4380, 2011 | 49 | 2011 |
Autophagy modulation as a treatment of amyloid diseases Z Mputhia, E Hone, T Tripathi, T Sargeant, R Martins, P Bharadwaj Molecules 24 (18), 3372, 2019 | 46 | 2019 |
Reduction in open field activity in the absence of memory deficits in the AppNL− G− F knock-in mouse model of Alzheimer’s disease LS Whyte, KM Hemsley, AA Lau, S Hassiotis, T Saito, TC Saido, ... Behavioural brain research 336, 177-181, 2018 | 45 | 2018 |
Rapamycin and Alzheimer disease: a double-edged sword? JM Carosi, TJ Sargeant Autophagy, 2019 | 44 | 2019 |
Acute in utero morphine exposure slows G2 / M phase transition in radial glial and basal progenitor cells in the dorsal telencephalon of the E15.5 embryonic … TJ Sargeant, DJ Day, JH Miller, RWJ Steel European Journal of Neuroscience 28 (6), 1060-1067, 2008 | 41 | 2008 |
Genetic variation within endolysosomal system is associated with late-onset Alzheimer’s disease S Gao, AE Casey, TJ Sargeant, VP Mäkinen Brain 141 (9), 2711-2720, 2018 | 37 | 2018 |
A 3-D in vitro co-culture model of mammary gland involution JJ Campbell, LA Botos, TJ Sargeant, N Davidenko, RE Cameron, ... Integrative Biology 6 (6), 618-626, 2014 | 30 | 2014 |
Mu opioid receptors are expressed on radial glia but not migrating neuroblasts in the late embryonic mouse brain TJ Sargeant, DJ Day, EM Mrkusich, DF Foo, JH Miller Brain research 1175, 28-38, 2007 | 29 | 2007 |
Stat3-mediated alterations in lysosomal membrane protein composition B Lloyd-Lewis, CC Krueger, TJ Sargeant, ME D’Angelo, MJ Deery, ... Journal of Biological Chemistry 293 (12), 4244-4261, 2018 | 24 | 2018 |
TNF, acting through inducibly expressed TNFR2, drives activation and cell cycle entry of c‐Kit+ cardiac stem cells in ischemic heart disease RS Al‐Lamki, W Lu, J Wang, J Yang, TJ Sargeant, R Wells, C Suo, ... Stem Cells 31 (9), 1881-1892, 2013 | 23 | 2013 |
Lysosomal LAMP 1 immunoreactivity exists in both diffuse and neuritic amyloid plaques in the human hippocampus S Hassiotis, J Manavis, PC Blumbergs, KJ Hattersley, JM Carosi, M Kamei, ... European Journal of Neuroscience 47 (9), 1043-1053, 2018 | 21 | 2018 |
Signal transducer and activator of transcription 3 and the phosphatidylinositol 3‐kinase regulatory subunits p55α and p50α regulate autophagy in vivo S Pensa, B Lloyd‐Lewis, TJ Sargeant, HK Resemann, CR Kahn, ... The FEBS Journal 281 (20), 4557-4567, 2014 | 20 | 2014 |
Characterization of inducible models of Tay-Sachs and related disease TJ Sargeant, DJ Drage, S Wang, AA Apostolakis, TM Cox, ... Public Library of Science 8 (9), e1002943, 2012 | 19 | 2012 |
A novel fluorescent probe reveals starvation controls the commitment of amyloid precursor protein to the lysosome LK Hein, PM Apaja, K Hattersley, RH Grose, J Xie, CG Proud, TJ Sargeant Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (10), 1554-1565, 2017 | 15 | 2017 |