Timothy J Sargeant
Timothy J Sargeant
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Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization
TJ Sargeant, B Lloyd-Lewis, HK Resemann, A Ramos-Montoya, ...
Nature cell biology 16 (11), 1057-1068, 2014
Endo‐lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?
LS Whyte, AA Lau, KM Hemsley, JJ Hopwood, TJ Sargeant
Journal of neurochemistry 140 (5), 703-717, 2017
Retromer has a selective function in cargo sorting via endosome transport carriers.
Y Cui, JM Carosi, Z Yang, N Ariotti, MC Kerr, RG Parton, TJ Sargeant, ...
Journal of Cell Biology, 2019
Opioidergic regulation of astroglial/neuronal proliferation: where are we now?
TJ Sargeant, JH Miller, DJ Day
Journal of neurochemistry 107 (4), 883-897, 2008
Guidelines for the use and interpretation of assays for monitoring autophagy 1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
Autophagy 17 (1), 1, 2021
Adeno-associated virus-mediated expression of β-hexosaminidase prevents neuronal loss in the Sandhoff mouse brain
TJ Sargeant, S Wang, J Bradley, NJC Smith, AA Raha, R McNair, ...
Human molecular genetics 20 (22), 4371-4380, 2011
Autophagy modulation as a treatment of amyloid diseases
Z Mputhia, E Hone, T Tripathi, T Sargeant, R Martins, P Bharadwaj
Molecules 24 (18), 3372, 2019
Reduction in open field activity in the absence of memory deficits in the AppNL− G− F knock-in mouse model of Alzheimer’s disease
LS Whyte, KM Hemsley, AA Lau, S Hassiotis, T Saito, TC Saido, ...
Behavioural brain research 336, 177-181, 2018
Rapamycin and Alzheimer disease: a double-edged sword?
JM Carosi, TJ Sargeant
Autophagy, 2019
Acute in utero morphine exposure slows G2 / M phase transition in radial glial and basal progenitor cells in the dorsal telencephalon of the E15.5 embryonic …
TJ Sargeant, DJ Day, JH Miller, RWJ Steel
European Journal of Neuroscience 28 (6), 1060-1067, 2008
Genetic variation within endolysosomal system is associated with late-onset Alzheimer’s disease
S Gao, AE Casey, TJ Sargeant, VP Mäkinen
Brain 141 (9), 2711-2720, 2018
A 3-D in vitro co-culture model of mammary gland involution
JJ Campbell, LA Botos, TJ Sargeant, N Davidenko, RE Cameron, ...
Integrative Biology 6 (6), 618-626, 2014
Mu opioid receptors are expressed on radial glia but not migrating neuroblasts in the late embryonic mouse brain
TJ Sargeant, DJ Day, EM Mrkusich, DF Foo, JH Miller
Brain research 1175, 28-38, 2007
Stat3-mediated alterations in lysosomal membrane protein composition
B Lloyd-Lewis, CC Krueger, TJ Sargeant, ME D’Angelo, MJ Deery, ...
Journal of Biological Chemistry 293 (12), 4244-4261, 2018
TNF, acting through inducibly expressed TNFR2, drives activation and cell cycle entry of c‐Kit+ cardiac stem cells in ischemic heart disease
RS Al‐Lamki, W Lu, J Wang, J Yang, TJ Sargeant, R Wells, C Suo, ...
Stem Cells 31 (9), 1881-1892, 2013
Lysosomal LAMP 1 immunoreactivity exists in both diffuse and neuritic amyloid plaques in the human hippocampus
S Hassiotis, J Manavis, PC Blumbergs, KJ Hattersley, JM Carosi, M Kamei, ...
European Journal of Neuroscience 47 (9), 1043-1053, 2018
Signal transducer and activator of transcription 3 and the phosphatidylinositol 3‐kinase regulatory subunits p55α and p50α regulate autophagy in vivo
S Pensa, B Lloyd‐Lewis, TJ Sargeant, HK Resemann, CR Kahn, ...
The FEBS Journal 281 (20), 4557-4567, 2014
Characterization of inducible models of Tay-Sachs and related disease
TJ Sargeant, DJ Drage, S Wang, AA Apostolakis, TM Cox, ...
Public Library of Science 8 (9), e1002943, 2012
A novel fluorescent probe reveals starvation controls the commitment of amyloid precursor protein to the lysosome
LK Hein, PM Apaja, K Hattersley, RH Grose, J Xie, CG Proud, TJ Sargeant
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (10), 1554-1565, 2017
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