Selective conversion of fibroblasts into peripheral sensory neurons JW Blanchard, KT Eade, A Szűcs, V Lo Sardo, RK Tsunemoto, D Williams, ... Nature neuroscience 18 (1), 25-35, 2015 | 181 | 2015 |
Serine and lipid metabolism in macular disease and peripheral neuropathy ML Gantner, K Eade, M Wallace, MK Handzlik, R Fallon, J Trombley, ... New England Journal of Medicine 381 (15), 1422-1433, 2019 | 174 | 2019 |
Diverse reprogramming codes for neuronal identity R Tsunemoto, S Lee, A Szűcs, P Chubukov, I Sokolova, JW Blanchard, ... Nature 557 (7705), 375-380, 2018 | 109 | 2018 |
Forward engineering neuronal diversity using direct reprogramming RK Tsunemoto, KT Eade, JW Blanchard, KK Baldwin The EMBO journal 34 (11), 1445-1455, 2015 | 48 | 2015 |
Cell-specific cis-regulatory elements and mechanisms of non-coding genetic disease in human retina and retinal organoids ED Thomas, AE Timms, S Giles, S Harkins-Perry, P Lyu, T Hoang, J Qian, ... Developmental cell 57 (6), 820-836. e6, 2022 | 35 | 2022 |
Developmental transcriptional networks are required to maintain neuronal subtype identity in the mature nervous system KT Eade, HA Fancher, MS Ridyard, DW Allan PLoS genetics 8 (2), e1002501, 2012 | 35 | 2012 |
Neuronal phenotype in the mature nervous system is maintained by persistent retrograde bone morphogenetic protein signaling KT Eade, DW Allan Journal of Neuroscience 29 (12), 3852-3864, 2009 | 35 | 2009 |
Lo Sardo V., Tsunemoto RK, Williams D., et al.(2015) JW Blanchard, KT Eade, A Szűcs Selective conversion of fibroblasts into peripheral sensory neurons. Nat …, 0 | 34 | |
Serine biosynthesis defect due to haploinsufficiency of PHGDH causes retinal disease K Eade, ML Gantner, JA Hostyk, T Nagasaki, S Giles, R Fallon, ... Nature metabolism 3 (3), 366-377, 2021 | 31 | 2021 |
Deletion of Tgfβ signal in activated microglia prolongs hypoxia‐induced retinal neovascularization enhancing Igf1 expression and retinal leukostasis A Usui‐Ouchi, K Eade, S Giles, Y Ideguchi, Y Ouchi, E Aguilar, G Wei, ... Glia 70 (9), 1762-1776, 2022 | 9 | 2022 |
Toxicity screens in human retinal organoids for pharmaceutical discovery K Eade, S Giles, S Harkins-Perry, M Friedlander JoVE (Journal of Visualized Experiments), e62269, 2021 | 8 | 2021 |
Integrating human iPSC‐derived macrophage progenitors into retinal organoids to generate a mature retinal microglial niche A Usui‐Ouchi, S Giles, S Harkins‐Perry, EA Mills, R Bonelli, G Wei, ... Glia 71 (10), 2372-2382, 2023 | 6 | 2023 |
Multi-omic analysis of developing human retina and organoids reveals cell-specific cis-regulatory elements and mechanisms of non-coding genetic disease risk ED Thomas, AE Timms, S Giles, S Harkins-Perry, P Lyu, T Hoang, J Qian, ... BioRxiv, 2021.07. 31.454254, 2021 | 6 | 2021 |
Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity JD Rosarda, S Giles, S Harkins-Perry, EA Mills, M Friedlander, ... Nature Communications 14 (1), 4119, 2023 | 4 | 2023 |
iPSC–derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function KT Eade, BRE Ansell, S Giles, R Fallon, S Harkins-Perry, T Nagasaki, ... The Journal of Clinical Investigation 133 (9), 2023 | 2 | 2023 |
Activity based checkpoints ensure circuit stability in the olfactory system KN James, BT Throesch, W Davini, KT Eade, S Ghosh, S Lee, ... bioRxiv, 156372, 2017 | 2 | 2017 |
Rare variants in the phosphoglycerate dehydrogenase (PHGDH) gene in MacTel patients lead to decreased enzymatic activity R Fallon, J Zernant, T Nagasaki, M Gantner, K Eade, R Allikmets, ... Investigative Ophthalmology & Visual Science 59 (9), 5409-5409, 2018 | 1 | 2018 |
Implications for iPS-based disease modeling: Significant variability is observed in RPE cells differentiated from identical sources ML Gantner, J Hazen, VL Sardo, K Eade, M Prins, PD Westenskow, ... Investigative Ophthalmology & Visual Science 57 (12), 6061-6061, 2016 | 1 | 2016 |
Impaired ceramide metabolism is associated with retinal changes in a model of tamoxifen retinopathy S Tzaridis, CR Green, ED Rubio, C Bates, Y Ideguchi, R Fallon, S Giles, ... Investigative Ophthalmology & Visual Science 64 (8), 3773-3773, 2023 | | 2023 |
Cover Image, Volume 70, Issue 9 A Usui‐Ouchi, K Eade, S Giles, Y Ideguchi, Y Ouchi, E Aguilar, G Wei, ... Glia 70 (9), C1-C1, 2022 | | 2022 |