|Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport—an update|
Q Mao, JD Unadkat
The AAPS journal 17 (1), 65-82, 2015
|Imaging P‐glycoprotein transport activity at the human blood‐brain barrier with positron emission tomography|
L Sasongko, JM Link, M Muzi, DA Mankoff, X Yang, AC Collier, ...
Clinical Pharmacology & Therapeutics 77 (6), 503-514, 2005
|Evaluation of the selectivity of in vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities|
D Hickman, JP Wang, YI Wang, JD Unadkat
Drug Metabolism and Disposition 26 (3), 207-215, 1998
|HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2)|
A Gupta, YI Zhang, JD Unadkat, Q Mao
Journal of pharmacology and experimental therapeutics 310 (1), 334-341, 2004
|The role of transporters in drug interactions|
CJ Endres, P Hsiao, FS Chung, JD Unadkat
european journal of pharmaceutical sciences 27 (5), 501-517, 2006
|Are we optimizing gestational diabetes treatment with glyburide? The pharmacologic basis for better clinical practice|
MF Hebert, X Ma, SB Naraharisetti, KM Krudys, JG Umans, GDV Hankins, ...
Clinical Pharmacology & Therapeutics 85 (6), 607-614, 2009
|Drug interactions at the blood-brain barrier: fact or fantasy?|
S Eyal, P Hsiao, JD Unadkat
Pharmacology & therapeutics 123 (1), 80-104, 2009
|Protein abundance of clinically relevant multidrug transporters along the entire length of the human intestine|
M Drozdzik, C Gröer, J Penski, J Lapczuk, M Ostrowski, Y Lai, B Prasad, ...
Molecular pharmaceutics 11 (10), 3547-3555, 2014
|Effects of pregnancy on CYP3A and P‐glycoprotein activities as measured by disposition of midazolam and digoxin: a University of Washington specialized center of research study|
MF Hebert, TR Easterling, B Kirby, DB Carr, ML Buchanan, T Rutherford, ...
Clinical Pharmacology & Therapeutics 84 (2), 248-253, 2008
|P-glycoprotein and breast cancer resistance protein expression in human placentae of various gestational ages|
AA Mathias, J Hitti, JD Unadkat
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2005
|Regulation of BCRP/ABCG2 expression by progesterone and 17β-estradiol in human placental BeWo cells|
H Wang, L Zhou, A Gupta, RR Vethanayagam, Y Zhang, JD Unadkat, ...
American Journal of Physiology-Endocrinology and Metabolism 290 (5), E798-E807, 2006
|Expression of arylamine N-acetyltransferase in human intestine|
D Hickman, J Pope, SD Patil, G Fakis, V Smelt, LA Stanley, M Payton, ...
Gut 42 (3), 402-409, 1998
|Mitochondrial expression of the human equilibrative nucleoside transporter 1 (hENT1) results in enhanced mitochondrial toxicity of antiviral drugs|
Y Lai, CM Tse, JD Unadkat
Journal of Biological Chemistry 279 (6), 4490-4497, 2004
|Simultaneous modeling of pharmacokinetics and pharmacodynamics with nonparametric kinetic and dynamic models|
JD Unadkat, F Bartha, LB Sheiner
Clinical Pharmacology & Therapeutics 40 (1), 86-93, 1986
|Pharmacokinetics of acyclovir in the term human pregnancy and neonate|
LM Frenkel, ZA Brown, YJ Bryson, L Corey, JD Unadkat, PA Hensleigh, ...
American journal of obstetrics and gynecology 164 (2), 569-576, 1991
|Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: implications for predicting clinical drug …|
V Dixit, N Hariparsad, F Li, P Desai, KE Thummel, JD Unadkat
Drug metabolism and disposition 35 (10), 1853-1859, 2007
|Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem …|
B Prasad, R Evers, A Gupta, CECA Hop, L Salphati, S Shukla, ...
Drug Metabolism and Disposition 42 (1), 78-88, 2014
|In situ hybridization and immunolocalization of concentrative and equilibrative nucleoside transporters in the human intestine, liver, kidneys, and placenta|
R Govindarajan, AH Bakken, KL Hudkins, Y Lai, FJ Casado, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2007
|Imaging of cyclosporine inhibition of P-glycoprotein activity using 11C-verapamil in the brain: studies of healthy humans|
M Muzi, DA Mankoff, JM Link, S Shoner, AC Collier, L Sasongko, ...
Journal of Nuclear Medicine 50 (8), 1267-1275, 2009
|The extent of metabolism of inhaled anesthetics in humans|
RL Carpenter, EI Eger, BH Johnson, JD Unadkat, LB Sheiner
Anesthesiology: The Journal of the American Society of Anesthesiologists 65 …, 1986