Steven Lane
Steven Lane
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TitleCited byYear
The leukemic stem cell niche: current concepts and therapeutic opportunities
SW Lane, DT Scadden, DG Gilliland
Blood, The Journal of the American Society of Hematology 114 (6), 1150-1157, 2009
Modulating the stem cell niche for tissue regeneration
SW Lane, DA Williams, FM Watt
Nature biotechnology 32 (8), 795-803, 2014
Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells
D Walter, A Lier, A Geiselhart, FB Thalheimer, S Huntscha, MC Sobotta, ...
Nature 520 (7548), 549, 2015
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia
MG Kharas, CJ Lengner, F Al-Shahrour, L Bullinger, B Ball, S Zaidi, ...
Nature medicine 16 (8), 903, 2010
BET inhibitor resistance emerges from leukaemia stem cells
CY Fong, O Gilan, EYN Lam, AF Rubin, S Ftouni, D Tyler, K Stanley, ...
Nature 525 (7570), 538, 2015
Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietic stem and progenitor cells
A Mullally, SW Lane, B Ball, C Megerdichian, R Okabe, F Al-Shahrour, ...
Cancer cell 17 (6), 584-596, 2010
AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias
SM Sykes, SW Lane, L Bullinger, D Kalaitzidis, R Yusuf, B Saez, F Ferraro, ...
Cell 146 (5), 697-708, 2011
Genetic and pharmacologic inhibition of β-catenin targets imatinib-resistant leukemia stem cells in CML
FH Heidel, L Bullinger, Z Feng, Z Wang, TA Neff, L Stein, D Kalaitzidis, ...
Cell stem cell 10 (4), 412-424, 2012
mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis
D Kalaitzidis, SM Sykes, Z Wang, N Punt, Y Tang, C Ragu, AU Sinha, ...
Cell stem cell 11 (3), 429-439, 2012
Differential niche and Wnt requirements during acute myeloid leukemia progression
SW Lane, YJ Wang, CL Celso, C Ragu, L Bullinger, SM Sykes, F Ferraro, ...
Blood 118 (10), 2849-2856, 2011
The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS
SW Lane, SM Sykes, F Al-Shahrour, S Shterental, M Paktinat, CL Celso, ...
Blood 115 (17), 3489-3497, 2010
Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera
A Mullally, C Bruedigam, L Poveromo, FH Heidel, A Purdon, T Vu, ...
Blood 121 (18), 3692-3702, 2013
Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo
P Zhang, SK Tey, M Koyama, RD Kuns, SD Olver, KE Lineburg, M Lor, ...
The Journal of Immunology 191 (10), 5291-5303, 2013
Leukemia stem cells
SW Lane, DG Gilliland
Seminars in cancer biology 20 (2), 71-76, 2010
Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies
C Joseph, JM Quach, CR Walkley, SW Lane, CL Celso, LE Purton
Cell stem cell 13 (5), 520-533, 2013
Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects
KH Gartlan, KA Markey, A Varelias, MD Bunting, M Koyama, RD Kuns, ...
Blood 126 (13), 1609-1620, 2015
Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy
C Bruedigam, FO Bagger, FH Heidel, CP Kuhn, S Guignes, A Song, ...
Cell Stem Cell 15 (6), 775-790, 2014
Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera
A Mullally, L Poveromo, RK Schneider, F Al-Shahrour, SW Lane, BL Ebert
Blood 120 (1), 166-172, 2012
A≥ 1 log rise in RQ-PCR transcript levels defines molecular relapse in core binding factor acute myeloid leukemia and predicts subsequent morphologic relapse
S Lane, R Saal, P Mollee, M Jones, A Grigg, K Taylor, J Seymour, ...
Leukemia & lymphoma 49 (3), 517-523, 2008
CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling
K Faber, L Bullinger, C Ragu, A Garding, D Mertens, C Miller, D Martin, ...
The Journal of clinical investigation 123 (1), 2012
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