Multidimensional heuristic process for high-yield production of astaxanthin and fragrance molecules in Escherichia coli C Zhang, VY Seow, X Chen, HP Too Nature Communications 9 (1), 1858, 2018 | 128 | 2018 |
Microbial astaxanthin biosynthesis: recent achievements, challenges, and commercialization outlook C Zhang, X Chen, HP Too Applied microbiology and biotechnology 104 (13), 5725-5737, 2020 | 118 | 2020 |
Systematic engineering for high-yield production of viridiflorol and amorphadiene in auxotrophic Escherichia coli S Shukal, X Chen, C Zhang Metabolic engineering 55, 170-178, 2019 | 86 | 2019 |
Optimization of amorphadiene synthesis in bacillus subtilis via transcriptional, translational, and media modulation K Zhou, R Zou, C Zhang, G Stephanopoulos, HP Too Biotechnology and bioengineering 110 (9), 2556-2561, 2013 | 86 | 2013 |
Efflux transporter engineering markedly improves amorphadiene production in Escherichia coli C Zhang, X Chen, G Stephanopoulos, HP Too Biotechnology and bioengineering 113 (8), 1755-1763, 2016 | 80 | 2016 |
A “plug‐n‐play” modular metabolic system for the production of apocarotenoids C Zhang, X Chen, ND Lindley, HP Too Biotechnology and bioengineering 115 (1), 174-183, 2018 | 70 | 2018 |
Combining genotype improvement and statistical media optimization for isoprenoid production in E. coli C Zhang, X Chen, R Zou, K Zhou, G Stephanopoulos, HP Too PLoS One 8 (10), e75164, 2013 | 68 | 2013 |
Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4, 11-diene X Chen, C Zhang, R Zou, K Zhou, G Stephanopoulos, HP Too PloS one 8 (11), e79650, 2013 | 55 | 2013 |
Biosynthesis of carotenoids and apocarotenoids by microorganisms and their industrial potential C Zhang Progress in carotenoid research 85, 2018 | 49 | 2018 |
Agrocybe aegerita Serves As a Gateway for Identifying Sesquiterpene Biosynthetic Enzymes in Higher Fungi C Zhang, X Chen, A Orban, S Shukal, F Birk, HP Too, M Rühl ACS Chemical Biology 15 (5), 1268-1277, 2020 | 48 | 2020 |
Metabolic engineering strategies for sustainable terpenoid flavor and fragrance synthesis X Chen, C Zhang, ND Lindley Journal of agricultural and food chemistry 68 (38), 10252-10264, 2019 | 46 | 2019 |
Experimental design-aided systematic pathway optimization of glucose uptake and deoxyxylulose phosphate pathway for improved amorphadiene production C Zhang, R Zou, X Chen, G Stephanopoulos, HP Too Applied microbiology and biotechnology 99, 3825-3837, 2015 | 43 | 2015 |
In Vitro Metabolic Engineering of Amorpha-4,11-diene Biosynthesis at Enhanced Rate and Specific Yield of Production X Chen, C Zhang, R Zou, G Stephanopoulos, HP Too ACS synthetic biology 6 (9), 1691-1700, 2017 | 30 | 2017 |
Microbial utilization of next-generation feedstocks for the biomanufacturing of value-added chemicals and food ingredients C Zhang, C Ottenheim, M Weingarten, L Ji Frontiers in Bioengineering and Biotechnology 10 (874612), 486, 2022 | 29 | 2022 |
Integrating enzyme and metabolic engineering tools for enhanced α-ionone production X Chen, S Shukal, C Zhang Journal of agricultural and food chemistry 67 (49), 13451-13459, 2019 | 27 | 2019 |
Bioinformatics-aided identification, characterization and applications of mushroom linalool synthases C Zhang, X Chen, RTC Lee, S Maurer-Stroh, M Rühl Communications Biology 4 (1), 223, 2021 | 25 | 2021 |
Multienzyme biosynthesis of dihydroartemisinic acid X Chen, C Zhang, HP Too Molecules 22 (9), 1422, 2017 | 22 | 2017 |
High-level de novo biosynthesis of glycosylated zeaxanthin and astaxanthin in Escherichia coli X Chen, X Lim, A Bouin, T Lautier, C Zhang Bioresources and Bioprocessing 8, 1-13, 2021 | 19 | 2021 |
Biotechnological applications of S-adenosyl-methionine-dependent methyltransferases for natural products biosynthesis and diversification C Zhang, SA Sultan, R T, X Chen Bioresources and Bioprocessing 8 (1), 1-21, 2021 | 17 | 2021 |
Metabolic engineering of Escherichia coli BL21 strain using simplified CRISPR-Cas9 and asymmetric homology arms recombineering S Shukal, XH Lim, C Zhang, X Chen Microbial Cell Factories 21 (1), 19, 2022 | 16 | 2022 |