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Sebastian Öther-Gee Pohl
Sebastian Öther-Gee Pohl
EACR/Boehringer Ingelheim Fellow, CRUK Scotland Centre - Institute of Genetics and Cancer, Edinburgh
Verified email at ed.ac.uk - Homepage
Title
Cited by
Cited by
Year
Wnt signaling in triple-negative breast cancer
SÖG Pohl, N Brook, M Agostino, F Arfuso, AP Kumar, A Dharmarajan
Oncogenesis 6 (4), e310-e310, 2017
2692017
The role of Wnt signalling in angiogenesis
JJ Olsen*, SÖG Pohl*, A Deshmukh, M Visweswaran, NC Ward, F Arfuso, ...
The Clinical Biochemist Reviews 38 (3), 131, 2017
1752017
Multi-lineage differentiation of mesenchymal stem cells–To Wnt, or not Wnt
M Visweswaran, S Pohl, F Arfuso, P Newsholme, R Dilley, S Pervaiz, ...
The international journal of biochemistry & cell biology 68, 139-147, 2015
1122015
Secreted frizzled-related protein 4 and its implications in cancer and apoptosis
S Pohl*, R Scott*, F Arfuso, V Perumal, A Dharmarajan
Tumor Biology 36, 143-152, 2015
582015
Structure-based prediction of Wnt binding affinities for Frizzled-type cysteine-rich domains
M Agostino, SÖG Pohl, A Dharmarajan
Journal of Biological Chemistry 292 (27), 11218-11229, 2017
362017
Cross talk between cellular redox state and the antiapoptotic protein Bcl-2
SÖG Pohl, M Agostino, A Dharmarajan, S Pervaiz
Antioxidants & Redox Signaling 29 (13), 1215-1236, 2018
332018
RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways
V Gudiño, SÖG Pohl, CV Billard, P Cammareri, A Bolado, S Aitken, ...
Nature Communications 12 (1), 2335, 2021
202021
Therapeutic approach to target mesothelioma cancer cells using the Wnt antagonist, secreted frizzled-related protein 4: metabolic state of cancer cells
V Perumal*, S Pohl*, KN Keane*, F Arfuso, P Newsholme, S Fox, ...
Experimental Cell Research 341 (2), 218-224, 2016
182016
Wnt binding affinity prediction for putative Frizzled-type cysteine-rich domains
M Agostino, SÖG Pohl
International journal of molecular sciences 20 (17), 4168, 2019
172019
The structural biology of canonical Wnt signalling
M Agostino, SÖG Pohl
Biochemical Society Transactions 48 (4), 1765-1780, 2020
152020
Gene expression analysis of heat-shock proteins and redox regulators reveals combinatorial prognostic markers in carcinomas of the gastrointestinal tract
SÖG Pohl, S Pervaiz, A Dharmarajan, M Agostino
Redox biology 25, 101060, 2019
142019
RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer
AE Hall*, SÖG Pohl*, P Cammareri, S Aitken, NT Younger, M Raponi, ...
Nature communications 13 (1), 2791, 2022
132022
Alternative RNA splicing in tumour heterogeneity, plasticity and therapy
S ÖG Pohl, KB Myant
Disease Models & Mechanisms 15 (1), dmm049233, 2022
112022
Design, synthesis, and biological evaluation of SSE1806, a microtubule destabilizer that overcomes multidrug resistance
F Firdous, S Riaz, M Furqan, S Fozail, K Fatima, SOG Pohl, NJ Doleschall, ...
ACS Medicinal Chemistry Letters, 2023
22023
Activation barriers in Class F G protein-coupled receptors revealed by umbrella sampling simulations
M Agostino, SÖG Pohl
Organic & Biomolecular Chemistry 18 (48), 9816-9825, 2020
22020
Synthesis and characterization of bis-amide SSE1917 as a microtubule-stabilizing anticancer agent
S Iqbal, F Firdous, M Furqan, A Bilal, S Fozail, SÖG Pohl, NJ Doleschall, ...
Bioorganic Chemistry 143, 107094, 2024
2024
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