TCR-or cytokine-activated CD8+ mucosal-associated invariant T cells are rapid polyfunctional effectors that can coordinate immune responses R Lamichhane, M Schneider, SM de la Harpe, TWR Harrop, ... Cell reports 28 (12), 3061-3076. e5, 2019 | 156 | 2019 |
The evolving small‐molecule fluorescent‐conjugate toolbox for C lass A GPCRs AJ Vernall, SJ Hill, B Kellam British journal of pharmacology 171 (5), 1073-1084, 2014 | 114 | 2014 |
Cross metathesis of nitrogen-containing systems A Vernall, A Abell Aldrich Chemical Co Inc, 2003 | 104 | 2003 |
Fragment screening at adenosine-A3 receptors in living cells using a fluorescence-based binding assay LA Stoddart, AJ Vernall, JL Denman, SJ Briddon, B Kellam, SJ Hill Chemistry & biology 19 (9), 1105-1115, 2012 | 103 | 2012 |
Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells LA Stoddart, AJ Vernall, M Bouzo-Lorenzo, R Bosma, AJ Kooistra, ... Scientific reports 8 (1), 1572, 2018 | 57 | 2018 |
Conversion of a non-selective adenosine receptor antagonist into A 3-selective high affinity fluorescent probes using peptide-based linkers AJ Vernall, LA Stoddart, SJ Briddon, HW Ng, CA Laughton, SW Doughty, ... Organic & biomolecular chemistry 11 (34), 5673-5682, 2013 | 54 | 2013 |
Type I interferons are important co‐stimulatory signals during T cell receptor mediated human MAIT cell activation R Lamichhane, H Galvin, RF Hannaway, SM de la Harpe, F Munro, ... European journal of immunology 50 (2), 178-191, 2020 | 53 | 2020 |
Highly Potent and Selective Fluorescent Antagonists of the Human Adenosine A3 Receptor Based on the 1,2,4-Triazolo[4,3-a]quinoxalin-1-one Scaffold AJ Vernall, LA Stoddart, SJ Briddon, SJ Hill, B Kellam Journal of medicinal chemistry 55 (4), 1771-1782, 2012 | 45 | 2012 |
Direct visualisation of internalization of the adenosine A3 receptor and localization with arrestin3 using a fluorescent agonist LA Stoddart, AJ Vernall, SJ Briddon, B Kellam, SJ Hill Neuropharmacology 98, 68-77, 2015 | 36 | 2015 |
Chromenopyrazole-based high affinity, selective fluorescent ligands for cannabinoid type 2 receptor S Singh, CRM Oyagawa, C Macdonald, NL Grimsey, M Glass, AJ Vernall ACS Medicinal Chemistry Letters 10 (2), 209-214, 2019 | 33 | 2019 |
Chemical tools for studying lipid-binding class AG protein–coupled receptors A Cooper, S Singh, S Hook, JDA Tyndall, AJ Vernall Pharmacological Reviews 69 (3), 316-353, 2017 | 32 | 2017 |
A Single α‐Helical Turn Stabilized by Replacement of an Internal Hydrogen Bond with a Covalent Ethylene Bridge AJ Vernall, P Cassidy, PF Alewood Angewandte Chemie International Edition 48 (31), 5675-5678, 2009 | 30 | 2009 |
Ring-deactivated hydroxyalkylpyrrole-based inhibitors of α-chymotrypsin: synthesis and mechanism of action DC Martyn, AJ Vernall, BM Clark, AD Abell Organic & biomolecular chemistry 1 (12), 2103-2110, 2003 | 29 | 2003 |
Developing the Cannabinoid Receptor 2 (CB2) pharmacopoeia: past, present, and future ZM Whiting, J Yin, SM de la Harpe, AJ Vernall, NL Grimsey Trends in Pharmacological Sciences 43 (9), 754-771, 2022 | 27 | 2022 |
Cannabinoid receptor 2 signalling bias elicited by 2, 4, 6-trisubstituted 1, 3, 5-triazines CRM Oyagawa, SM de la Harpe, Y Saroz, M Glass, AJ Vernall, ... Frontiers in pharmacology 9, 419509, 2018 | 27 | 2018 |
Human liver‐derived MAIT cells differ from blood MAIT cells in their metabolism and response to TCR‐independent activation R Lamichhane, F Munro, TWR Harrop, SM de la Harpe, PK Dearden, ... European Journal of Immunology 51 (4), 879-892, 2021 | 21 | 2021 |
Alkyl indole-based cannabinoid type 2 receptor tools: Exploration of linker and fluorophore attachment AG Cooper, C MacDonald, M Glass, S Hook, JDA Tyndall, AJ Vernall European Journal of Medicinal Chemistry 145, 770-789, 2018 | 21 | 2018 |
Development of selective, fluorescent cannabinoid type 2 receptor ligands based on a 1, 8-naphthyridin-2-(1 H)-one-3-carboxamide scaffold AG Cooper, CRM Oyagawa, JJ Manning, S Singh, S Hook, NL Grimsey, ... Medchemcomm 9 (12), 2055-2067, 2018 | 21 | 2018 |
Cross-metathesis coupling of sugars and fatty acids to lysine and cysteine AJ Vernall, AD Abell Organic & biomolecular chemistry 2 (18), 2555-2557, 2004 | 21 | 2004 |
Cross-metathesis and ring-closing metathesis reactions of amino acid-based substrates AJ Vernall, S Ballet, AD Abell Tetrahedron 64 (18), 3980-3997, 2008 | 19 | 2008 |