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(Jack) Wei Chen
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Year
Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling
B Liu, W Chen, BD Evavold, C Zhu
Cell 157 (2), 357-368, 2014
5692014
T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex
JJ Adams, S Narayanan, B Liu, ME Birnbaum, AC Kruse, NA Bowerman, ...
Immunity 35 (5), 681-693, 2011
2852011
Forcing switch from short-to intermediate-and long-lived states of the αA domain generates LFA-1/ICAM-1 catch bonds
W Chen, J Lou, C Zhu
Journal of Biological Chemistry 285 (46), 35967-35978, 2010
2132010
Flow-enhanced adhesion regulated by a selectin interdomain hinge
J Lou, T Yago, AG Klopocki, P Mehta, W Chen, VI Zarnitsyna, NV Bovin, ...
The Journal of cell biology 174 (7), 1107-1117, 2006
1872006
Observing force-regulated conformational changes and ligand dissociation from a single integrin on cells
W Chen, J Lou, EA Evans, C Zhu
Journal of Cell Biology 199 (3), 497-512, 2012
1732012
Liquid–liquid phase separation by SARS-CoV-2 nucleocapsid protein and RNA
H Chen, Y Cui, X Han, W Hu, M Sun, Y Zhang, PH Wang, G Song, ...
Cell research 30 (12), 1143-1145, 2020
1422020
Mechanosensing through immunoreceptors
C Zhu, W Chen, J Lou, W Rittase, K Li
Nature immunology 20 (10), 1269-1278, 2019
1392019
Monitoring receptor-ligand interactions between surfaces by thermal fluctuations
W Chen, EA Evans, RP McEver, C Zhu
Biophysical journal 94 (2), 694-701, 2008
1362008
Mechanical regulation of T‐cell functions
W Chen, C Zhu
Immunological reviews 256 (1), 160-176, 2013
1092013
Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition
P Wu, T Zhang, B Liu, P Fei, L Cui, R Qin, H Zhu, D Yao, RJ Martinez, ...
Molecular cell 73 (5), 1015-1027, 2019
1062019
Measuring receptor–ligand binding kinetics on cell surfaces: from adhesion frequency to thermal fluctuation methods
W Chen, VI Zarnitsyna, KK Sarangapani, J Huang, C Zhu
Cellular and molecular bioengineering 1, 276-288, 2008
1012008
Molecular force spectroscopy on cells
B Liu, W Chen, C Zhu
Annual review of physical chemistry 66, 427-451, 2015
712015
Dynamic control of β1 integrin adhesion by the plexinD1-sema3E axis
YI Choi, JS Duke-Cohan, W Chen, B Liu, J Rossy, T Tabarin, L Ju, J Gui, ...
Proceedings of the National Academy of Sciences 111 (1), 379-384, 2014
712014
Triphasic force dependence of E-selectin/ligand dissociation governs cell rolling under flow
AM Wayman, W Chen, RP McEver, C Zhu
Biophysical journal 99 (4), 1166-1174, 2010
662010
Regulation of catch bonds by rate of force application
KK Sarangapani, J Qian, W Chen, VI Zarnitsyna, P Mehta, T Yago, ...
Journal of Biological Chemistry 286 (37), 32749-32761, 2011
652011
Fluorescence biomembrane force probe: concurrent quantitation of receptor-ligand kinetics and binding-induced intracellular signaling on a single cell
Y Chen, B Liu, L Ju, J Hong, Q Ji, W Chen, C Zhu
JoVE (Journal of Visualized Experiments), e52975, 2015
562015
Substrate stiffness governs the initiation of B cell activation by the concerted signaling of PKCβ and focal adhesion kinase
S Shaheen, Z Wan, Z Li, A Chau, X Li, S Zhang, Y Liu, J Yi, Y Zeng, ...
Elife 6, e23060, 2017
542017
The cellular environment regulates in situ kinetics of T‐cell receptor interaction with peptide major histocompatibility complex
B Liu, W Chen, K Natarajan, Z Li, DH Margulies, C Zhu
European journal of immunology 45 (7), 2099-2110, 2015
492015
Mechanical activation of spike fosters SARS-CoV-2 viral infection
W Hu, Y Zhang, P Fei, T Zhang, D Yao, Y Gao, J Liu, H Chen, Q Lu, ...
Cell Research 31 (10), 1047-1060, 2021
362021
NKG2D discriminates diverse ligands through selectively mechano‐regulated ligand conformational changes
J Fan, J Shi, Y Zhang, J Liu, C An, H Zhu, P Wu, W Hu, R Qin, D Yao, ...
The EMBO Journal 41 (2), e107739, 2022
282022
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Articles 1–20