| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13467* | 2021 |
| DEPTOR, an mTOR inhibitor, is a physiological substrate of SCFβTrCP E3 ubiquitin ligase and regulates survival and autophagy Y Zhao, X Xiong, Y Sun Molecular cell 44 (2), 304-316, 2011 | 301 | 2011 |
| Cullin-RING Ligases as attractive anti-cancer targets Y Zhao, Y Sun Current pharmaceutical design 19 (18), 3215-3225, 2013 | 277 | 2013 |
| PROTACs: an emerging targeting technique for protein degradation in drug discovery S Gu, D Cui, X Chen, X Xiong, Y Zhao BioEssays 40 (4), 1700247, 2018 | 201 | 2018 |
| Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy Y Zhao, MA Morgan, Y Sun Antioxidants & redox signaling 21 (17), 2383-2400, 2014 | 195 | 2014 |
| Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis Y Zhao, X Xiong, L Jia, Y Sun Cell death & disease 3 (9), e386-e386, 2012 | 149 | 2012 |
| Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis as a target, a substrate and a regulator X Xiong, Y Zhao, H He, Y Sun Oncogene 30 (15), 1798-1811, 2011 | 142 | 2011 |
| SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation M Tan, Y Zhao, SJ Kim, M Liu, L Jia, TL Saunders, Y Zhu, Y Sun Developmental cell 21 (6), 1062-1076, 2011 | 86 | 2011 |
| Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis H Li, M Tan, L Jia, D Wei, Y Zhao, G Chen, J Xu, L Zhao, D Thomas, ... The Journal of clinical investigation 124 (2), 835-846, 2014 | 82 | 2014 |
| Targeting the mTOR-DEPTOR pathway by CRL E3 ubiquitin ligases: therapeutic application Y Zhao, Y Sun Neoplasia 14 (5), 360-367, 2012 | 68 | 2012 |
| The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor J Xu, W Zhou, F Yang, G Chen, H Li, Y Zhao, P Liu, H Li, M Tan, X Xiong, ... Nature communications 8 (1), 14002, 2017 | 66 | 2017 |
| Cullin-RING ligases in regulation of autophagy D Cui, X Xiong, Y Zhao Cell division 11, 1-14, 2016 | 66 | 2016 |
| FBXW7 confers radiation survival by targeting p53 for degradation D Cui, X Xiong, J Shu, X Dai, Y Sun, Y Zhao Cell reports 30 (2), 497-509. e4, 2020 | 63 | 2020 |
| Blockage of neddylation modification stimulates tumor sphere formation in vitro and stem cell differentiation and wound healing in vivo X Zhou, M Tan, MK Nyati, Y Zhao, G Wang, Y Sun Proceedings of the National Academy of Sciences 113 (21), E2935-E2944, 2016 | 60 | 2016 |
| Smac-mimetic compound SM-164 induces radiosensitization in breast cancer cells through activation of caspases and induction of apoptosis D Yang, Y Zhao, AY Li, S Wang, G Wang, Y Sun Breast cancer research and treatment 133, 189-199, 2012 | 55 | 2012 |
| Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis X Xiong, Y Zhao, F Tang, D Wei, D Thomas, X Wang, Y Liu, P Zheng, ... elife 3, e02236, 2014 | 53 | 2014 |
| Cullin-RING Ligase 5: Functional characterization and its role in human cancers Y Zhao, X Xiong, Y Sun Seminars in Cancer Biology 67, 61-79, 2020 | 47 | 2020 |
| The potassium channel KCa3. 1 promotes cell proliferation by activating SKP2 and metastasis through the EMT pathway in hepatocellular carcinoma Y Du, W Song, J Chen, H Chen, Z Xuan, L Zhao, J Chen, C Jin, M Zhou, ... International journal of cancer 145 (2), 503-516, 2019 | 46 | 2019 |
| The characteristics and roles of β‐TrCP1/2 in carcinogenesis Y Bi, D Cui, X Xiong, Y Zhao The FEBS journal 288 (11), 3351-3374, 2021 | 40 | 2021 |
| The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth D Cui, X Dai, J Shu, Y Ma, D Wei, X Xiong, Y Zhao Cell Death & Differentiation 27 (3), 1119-1133, 2020 | 40 | 2020 |
