James N. Ihle
James N. Ihle
Chairman, Department of Biochemistry, St. Jude Children's Research Hospital
Verified email at stjude.org
Cited by
Cited by
Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
HU Wang, ZF Chen, DJ Anderson
Cell 93 (5), 741-753, 1998
STATs: signal transducers and activators of transcription
JN Ihle
Cell 84 (3), 331-334, 1996
Cytokine receptor signalling
JN Ihle
Nature 377 (6550), 591-594, 1995
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
K Shimoda, J van Deursent, MY Sangster, SR Sarawar, RT Carson, ...
Nature 380 (6575), 630-633, 1996
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
S Teglund, C McKay, E Schuetz, JM Van Deursen, D Stravopodis, ...
Cell 93 (5), 841-850, 1998
JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
BA Witthuhn, FW Quelle, O Silvennoinen, T Yi, B Tang, O Miura, JN Ihle
Cell 74 (2), 227-236, 1993
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
WE Thierfelder, JM van Deursen, K Yamamoto, RA Tripp, SR Sarawar, ...
Nature 382 (6587), 171-174, 1996
Jak2 is essential for signaling through a variety of cytokine receptors
E Parganas, D Wang, D Stravopodis, DJ Topham, JC Marine, S Teglund, ...
Cell 93 (3), 385-395, 1998
Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase
LS Argetsinger, GS Campbell, X Yang, BA Witthuhn, O Silvennoinen, ...
Cell 74 (2), 237-244, 1993
Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 β receptor components
N Stahl, TG Boulton, T Farruggella, NY Ip, S Davis, BA Witthuhn, ...
Science 263 (5143), 92-95, 1994
Gene-marking to trace origin of relapse after autologous bone-marrow transplantation
MK Brenner, DR Rill, RA Krance, JN Ihle, RC Moen, J Mirro, WF Anderson
The Lancet 341 (8837), 85-86, 1993
Jaks and Stats in signaling by the cytokine receptor superfamily
JN Ihle, IM Kerr
Trends in Genetics 11 (2), 69-74, 1995
Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors
K Ikebuchi, GG Wong, SC Clark, JN Ihle, Y Hirai, M Ogawa
Proceedings of the National Academy of Sciences 84 (24), 9035-9039, 1987
Puma is an essential mediator of p53-dependent and-independent apoptotic pathways
JR Jeffers, E Parganas, Y Lee, C Yang, JL Wang, J Brennan, ...
Cancer cell 4 (4), 321-328, 2003
Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, p cell-stimulating factor activity …
JN Ihle, J Keller, S Oroszlan, LE Henderson, TD Copeland, F Fitch, ...
The Journal of Immunology 131 (1), 282-287, 1983
The JAK‐binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
H Yasukawa, H Misawa, H Sakamoto, M Masuhara, A Sasaki, T Wakioka, ...
The EMBO journal 18 (5), 1309-1320, 1999
The protein tyrosine kinase JAK1 complements defects in interferon-α/β and-γ signal transduction
M Müller, J Briscoe, C Laxton, D Guschin, A Ziemiecki, O Silvennoinen, ...
Nature 366 (6451), 129-135, 1993
The Stat family in cytokine signaling
JN Ihle
Current opinion in cell biology 13 (2), 211-217, 2001
Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene
LD Shultz, PA Schweitzer, TV Rajan, T Yi, JN Ihle, RJ Matthews, ...
Cell 73 (7), 1445-1454, 1993
Signaling by the cytokine receptor superfamily: JAKs and STATs
JN Ihle, BA Witthuhn, FW Quelle, K Yamamoto, WE Thierfelder, B Kreider, ...
Trends in biochemical sciences 19 (5), 222-227, 1994
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