Using recursive feature elimination in random forest to account for correlated variables in high dimensional data BF Darst, KC Malecki, CD Engelman BMC genetics 19, 1-6, 2018 | 508 | 2018 |
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction DV Conti, BF Darst, LC Moss, EJ Saunders, X Sheng, A Chou, ... Nature genetics 53 (1), 65-75, 2021 | 393 | 2021 |
The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease NM Vogt, KA Romano, BF Darst, CD Engelman, SC Johnson, ... Alzheimer's research & therapy 10, 1-8, 2018 | 382 | 2018 |
Multimodal imaging of the self-regulating developing brain AM Fjell, KB Walhovd, TT Brown, JM Kuperman, Y Chung, DJ Hagler Jr, ... Proceedings of the National Academy of Sciences 109 (48), 19620-19625, 2012 | 284 | 2012 |
Long-term influence of normal variation in neonatal characteristics on human brain development KB Walhovd, AM Fjell, TT Brown, JM Kuperman, Y Chung, DJ Hagler Jr, ... Proceedings of the National Academy of Sciences 109 (49), 20089-20094, 2012 | 217 | 2012 |
Longitudinal plasma metabolomics of aging and sex BF Darst, RL Koscik, KJ Hogan, SC Johnson, CD Engelman Aging (Albany NY) 11 (4), 1262, 2019 | 188 | 2019 |
Impact of direct-to-consumer genomic testing at long term follow-up CS Bloss, NE Wineinger, BF Darst, NJ Schork, EJ Topol Journal of medical genetics 50 (6), 393-400, 2013 | 174 | 2013 |
Pathway-specific polygenic risk scores as predictors of amyloid-β deposition and cognitive function in a sample at increased risk for Alzheimer’s disease BF Darst, RL Koscik, AM Racine, JM Oh, RA Krause, CM Carlsson, ... Journal of Alzheimer’s Disease 55 (2), 473-484, 2016 | 140 | 2016 |
Genome‐wide association study of shared components of reading disability and language impairment JD Eicher, NR Powers, LL Miller, N Akshoomoff, DG Amaral, CS Bloss, ... Genes, Brain and Behavior 12 (8), 792-801, 2013 | 119 | 2013 |
Direct-to-consumer personalized genomic testing CS Bloss, BF Darst, EJ Topol, NJ Schork Human Molecular Genetics 20 (R2), R132-R141, 2011 | 117 | 2011 |
Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations DJ Panyard, KM Kim, BF Darst, YK Deming, X Zhong, Y Wu, H Kang, ... Communications biology 4 (1), 63, 2021 | 92 | 2021 |
Evidence for the role of EP HX2 gene variants in anorexia nervosa SV Zeeland, CS Bloss, R Tewhey, V Bansal, A Torkamani, O Libiger, ... Molecular psychiatry 19 (6), 724-732, 2014 | 83 | 2014 |
Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals K Hou, Y Ding, Z Xu, Y Wu, A Bhattacharya, R Mester, GM Belbin, ... Nature genetics 55 (4), 549-558, 2023 | 79 | 2023 |
BDNF Val66Met predicts cognitive decline in the Wisconsin Registry for Alzheimer's Prevention EA Boots, SA Schultz, LR Clark, AM Racine, BF Darst, RL Koscik, ... Neurology 88 (22), 2098-2106, 2017 | 76 | 2017 |
Germline sequencing DNA repair genes in 5545 men with aggressive and nonaggressive prostate cancer BF Darst, T Dadaev, E Saunders, X Sheng, P Wan, L Pooler, LY Xia, ... JNCI: Journal of the National Cancer Institute 113 (5), 616-625, 2021 | 69 | 2021 |
Combined effect of a polygenic risk score and rare genetic variants on prostate cancer risk BF Darst, X Sheng, RA Eeles, Z Kote-Jarai, DV Conti, CA Haiman European urology 80 (2), 134-138, 2021 | 65 | 2021 |
KLOTHO heterozygosity attenuates APOE4-related amyloid burden in preclinical AD CM Erickson, SA Schultz, JM Oh, BF Darst, Y Ma, D Norton, T Betthauser, ... Neurology 92 (16), e1878-e1889, 2019 | 65 | 2019 |
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants A Wang, J Shen, AA Rodriguez, EJ Saunders, F Chen, R Janivara, ... Nature genetics 55 (12), 2065-2074, 2023 | 61 | 2023 |
Genetic discovery and risk characterization in type 2 diabetes across diverse populations LM Polfus, BF Darst, H Highland, X Sheng, MCY Ng, JE Below, L Petty, ... Human Genetics and Genomics Advances 2 (2), 2021 | 50 | 2021 |
Integrated analysis of genomics, longitudinal metabolomics, and Alzheimer's risk factors among 1,111 cohort participants BF Darst, Q Lu, SC Johnson, CD Engelman Genetic epidemiology 43 (6), 657-674, 2019 | 50 | 2019 |