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Ghassan Maghzal
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Insulin resistance is a cellular antioxidant defense mechanism
KL Hoehn, AB Salmon, C Hohnen-Behrens, N Turner, AJ Hoy, ...
Proceedings of the National Academy of Sciences 106 (42), 17787-17792, 2009
6072009
The high reactivity of peroxiredoxin 2 with H2O2 is not reflected in its reaction with other oxidants and thiol reagents
AV Peskin, FM Low, LN Paton, GJ Maghzal, MB Hampton, ...
Journal of Biological Chemistry 282 (16), 11885-11892, 2007
4432007
NAD deficiency, congenital malformations, and niacin supplementation
H Shi, A Enriquez, M Rapadas, EMMA Martin, R Wang, J Moreau, CK Lim, ...
New England Journal of Medicine 377 (6), 544-552, 2017
2282017
Reactivation of dihydroorotate dehydrogenase-driven pyrimidine biosynthesis restores tumor growth of respiration-deficient cancer cells
M Bajzikova, J Kovarova, AR Coelho, S Boukalova, S Oh, K Rohlenova, ...
Cell metabolism 29 (2), 399-416. e10, 2019
2082019
The roles of myeloperoxidase in coronary artery disease and its potential implication in plaque rupture
N Teng, GJ Maghzal, J Talib, I Rashid, AK Lau, R Stocker
Redox Report 22 (2), 51-73, 2017
1992017
Detection of reactive oxygen species derived from the family of NOX NADPH oxidases
GJ Maghzal, KH Krause, R Stocker, V Jaquet
Free Radical Biology and Medicine 53 (10), 1903-1918, 2012
1882012
Pharmacological characterization of the seven human NOX isoforms and their inhibitors
F Augsburger, A Filippova, D Rasti, T Seredenina, M Lam, G Maghzal, ...
Redox biology 26, 101272, 2019
1572019
Reactive oxygen-related diseases: therapeutic targets and emerging clinical indications
AI Casas, VTV Dao, A Daiber, GJ Maghzal, F Di Lisa, N Kaludercic, ...
Antioxidants & redox signaling 23 (14), 1171-1185, 2015
1482015
Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: a critical role for heme oxygenase-1
Y Shen, NC Ward, JM Hodgson, IB Puddey, Y Wang, D Zhang, ...
Free Radical Biology and Medicine 65, 908-915, 2013
1472013
The lipocalin α1-microglobulin has radical scavenging activity
B Akerstrom, GJ Maghzal, CC Winterbourn, AJ Kettle
Journal of Biological Chemistry 282 (43), 31493-31503, 2007
1442007
Near-infrared autofluorescence induced by intraplaque hemorrhage and heme degradation as marker for high-risk atherosclerotic plaques
NM Htun, YC Chen, B Lim, T Schiller, GJ Maghzal, AL Huang, KD Elgass, ...
Nature communications 8 (1), 75, 2017
1302017
Limited role for the bilirubin-biliverdin redox amplification cycle in the cellular antioxidant protection by biliverdin reductase
GJ Maghzal, MC Leck, E Collinson, C Li, R Stocker
Journal of biological chemistry 284 (43), 29251-29259, 2009
1272009
Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation
DJ Fazakerley, AY Minard, JR Krycer, KC Thomas, J Stöckli, DJ Harney, ...
Journal of Biological Chemistry 293 (19), 7315-7328, 2018
1262018
Myeloperoxidase is a potential molecular imaging and therapeutic target for the identification and stabilization of high-risk atherosclerotic plaque
I Rashid, GJ Maghzal, YC Chen, D Cheng, J Talib, D Newington, M Ren, ...
European heart journal 39 (35), 3301-3310, 2018
1182018
Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis
D Changsirivathanathamrong, Y Wang, D Rajbhandari, GJ Maghzal, ...
Critical care medicine 39 (12), 2678-2683, 2011
1172011
Inhibition of MPO (myeloperoxidase) attenuates endothelial dysfunction in mouse models of vascular inflammation and atherosclerosis
D Cheng, J Talib, CP Stanley, I Rashid, E Michaëlsson, EL Lindstedt, ...
Arteriosclerosis, thrombosis, and vascular biology 39 (7), 1448-1457, 2019
1132019
Novel fibrinogen γ375 Arg→ Trp mutation (fibrinogen Aguadilla) causes hepatic endoplasmic reticulum storage and hypofibrinogenemia
SO Brennan, G Maghzal, BL Shneider, R Gordon, MS Magid, PM George
Hepatology 36 (3), 652-658, 2002
1122002
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance
DJ Fazakerley, R Chaudhuri, P Yang, GJ Maghzal, KC Thomas, JR Krycer, ...
Elife 7, e32111, 2018
1112018
Flavonoid‐rich apple improves endothelial function in individuals at risk for cardiovascular disease: a randomized controlled clinical trial
NP Bondonno, CP Bondonno, LC Blekkenhorst, MJ Considine, ...
Molecular Nutrition & Food Research 62 (3), 1700674, 2018
1052018
Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2, 3-dioxygenase in human cells
GJ Maghzal, SR Thomas, NH Hunt, R Stocker
Journal of biological chemistry 283 (18), 12014-12025, 2008
1022008
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