josef vlasak
josef vlasak
Verified email at merck.com
Title
Cited by
Cited by
Year
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infection
TW Baba, V Liska, R Hofmann-Lehmann, J Vlasak, W Xu, S Ayehunie, ...
Nature medicine 6 (2), 200, 2000
10452000
Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies
RM Ionescu, J Vlasak, C Price, M Kirchmeier
Journal of pharmaceutical sciences 97 (4), 1414-1426, 2008
2912008
Heterogeneity of monoclonal antibodies revealed by charge-sensitive methods
J Vlasak, R Ionescu
Current pharmaceutical biotechnology 9 (6), 468-481, 2008
2632008
Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody
J Vlasak, MC Bussat, S Wang, E Wagner-Rousset, M Schaefer, ...
Analytical biochemistry 392 (2), 145-154, 2009
2042009
Impact of methionine oxidation in human IgG1 Fc on serum half-life of monoclonal antibodies
W Wang, J Vlasak, Y Li, P Pristatsky, Y Fang, T Pittman, J Roman, Y Wang, ...
Molecular immunology 48 (6-7), 860-866, 2011
1982011
Postnatal passive immunization of neonatal macaques with a triple combination of human monoclonal antibodies against oral simian-human immunodeficiency virus challenge
R Hofmann-Lehmann, J Vlasak, RA Rasmussen, BA Smith, TW Baba, ...
Journal of virology 75 (16), 7470-7480, 2001
1962001
Fragmentation of monoclonal antibodies
J Vlasak, R Ionescu
MAbs 3 (3), 253-263, 2011
1942011
Impact of methionine oxidation on the binding of human IgG1 to FcRn and Fcγ receptors
A Bertolotti-Ciarlet, W Wang, R Lownes, P Pristatsky, Y Fang, T McKelvey, ...
Molecular immunology 46 (8-9), 1878-1882, 2009
1912009
Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation
R Hofmann-Lehmann, J Vlasak, AL Williams, AL Chenine, HM McClure, ...
Aids 17 (2), 157-166, 2003
1462003
β-Elimination and peptide bond hydrolysis: two distinct mechanisms of human IgG1 hinge fragmentation upon storage
SL Cohen, C Price, J Vlasak
Journal of the American Chemical Society 129 (22), 6976-6977, 2007
1312007
Effect of protein structure on deamidation rate in the Fc fragment of an IgG1 monoclonal antibody
S Sinha, L Zhang, S Duan, TD Williams, J Vlasak, R Ionescu, EM Topp
Protein Science 18 (8), 1573-1584, 2009
752009
Evidence for trisulfide bonds in a recombinant variant of a human IgG2 monoclonal antibody
P Pristatsky, SL Cohen, D Krantz, J Acevedo, R Ionescu, J Vlasak
Analytical chemistry 81 (15), 6148-6155, 2009
702009
Postnatal pre‐and postexposure passive immunization strategies: protection of neonatal macaques against oral simian–human immunodeficiency virus challenge
R Hofmann‐Lehmann, J Vlasak, RA Rasmussen, S Jiang, PL Li, TW Baba, ...
Journal of medical primatology 31 (3), 109-119, 2002
652002
Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies
RM Ruprecht, R Hofmann-Lehmann, BA Smith-Franklin, RA Rasmussen, ...
Transfusion clinique et biologique 8 (4), 350-358, 2001
622001
Neutralizing antibodies as a potential secondary protective mechanism during chronic SHIV infection in CD8+ T-cell-depleted macaques
RA Rasmussen, R Hofmann-Lehmann, PL Li, J Vlasak, JE Schmitz, ...
Aids 16 (6), 829-838, 2002
582002
Isolation and characterization of IgG1 with asymmetrical Fc glycosylation
S Ha, Y Ou, J Vlasak, Y Li, S Wang, K Vo, Y Du, A Mach, Y Fang, N Zhang
Glycobiology 21 (8), 1087-1096, 2011
562011
DNA prime/protein boost vaccine strategy in neonatal macaques against simian human immunodeficiency virus
RA Rasmussen, R Hofmann‐Lehmann, DC Montefiori, PL Li, V Liska, ...
Journal of medical primatology 31 (1), 40-60, 2002
472002
Passive immunization against oral AIDS virus transmission: An approach to prevent mother‐to‐infant HIV‐1 transmission?
R Hofmann‐Lehmann, RA Rasmussen, J Vlasak, BA Smith, TW Baba, ...
Journal of medical primatology 30 (4), 190-196, 2001
472001
Neutralization of diverse human cytomegalovirus strains conferred by antibodies targeting viral gH/gL/pUL128-131 pentameric complex
S Ha, F Li, MC Troutman, DC Freed, A Tang, JW Loughney, D Wang, ...
Journal of virology 91 (7), e02033-16, 2017
442017
Separation of post-translational modifications in monoclonal antibodies by exploiting subtle conformational changes under mildly acidic conditions
S Wang, R Ionescu, N Peekhaus, J Leung, S Ha, J Vlasak
Journal of Chromatography A 1217 (42), 6496-6502, 2010
362010
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