josef vlasak
josef vlasak
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Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infection
TW Baba, V Liska, R Hofmann-Lehmann, J Vlasak, W Xu, S Ayehunie, ...
Nature medicine 6 (2), 200, 2000
Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies
RM Ionescu, J Vlasak, C Price, M Kirchmeier
Journal of pharmaceutical sciences 97 (4), 1414-1426, 2008
Heterogeneity of monoclonal antibodies revealed by charge-sensitive methods
J Vlasak, R Ionescu
Current pharmaceutical biotechnology 9 (6), 468-481, 2008
Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody
J Vlasak, MC Bussat, S Wang, E Wagner-Rousset, M Schaefer, ...
Analytical biochemistry 392 (2), 145-154, 2009
Impact of methionine oxidation in human IgG1 Fc on serum half-life of monoclonal antibodies
W Wang, J Vlasak, Y Li, P Pristatsky, Y Fang, T Pittman, J Roman, Y Wang, ...
Molecular immunology 48 (6-7), 860-866, 2011
Postnatal passive immunization of neonatal macaques with a triple combination of human monoclonal antibodies against oral simian-human immunodeficiency virus challenge
R Hofmann-Lehmann, J Vlasak, RA Rasmussen, BA Smith, TW Baba, ...
Journal of virology 75 (16), 7470-7480, 2001
Fragmentation of monoclonal antibodies
J Vlasak, R Ionescu
MAbs 3 (3), 253-263, 2011
Impact of methionine oxidation on the binding of human IgG1 to FcRn and Fcγ receptors
A Bertolotti-Ciarlet, W Wang, R Lownes, P Pristatsky, Y Fang, T McKelvey, ...
Molecular immunology 46 (8-9), 1878-1882, 2009
Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation
R Hofmann-Lehmann, J Vlasak, AL Williams, AL Chenine, HM McClure, ...
Aids 17 (2), 157-166, 2003
β-Elimination and peptide bond hydrolysis: two distinct mechanisms of human IgG1 hinge fragmentation upon storage
SL Cohen, C Price, J Vlasak
Journal of the American Chemical Society 129 (22), 6976-6977, 2007
Effect of protein structure on deamidation rate in the Fc fragment of an IgG1 monoclonal antibody
S Sinha, L Zhang, S Duan, TD Williams, J Vlasak, R Ionescu, EM Topp
Protein Science 18 (8), 1573-1584, 2009
Evidence for trisulfide bonds in a recombinant variant of a human IgG2 monoclonal antibody
P Pristatsky, SL Cohen, D Krantz, J Acevedo, R Ionescu, J Vlasak
Analytical chemistry 81 (15), 6148-6155, 2009
Postnatal pre‐and postexposure passive immunization strategies: protection of neonatal macaques against oral simian–human immunodeficiency virus challenge
R Hofmann‐Lehmann, J Vlasak, RA Rasmussen, S Jiang, PL Li, TW Baba, ...
Journal of medical primatology 31 (3), 109-119, 2002
Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies
RM Ruprecht, R Hofmann-Lehmann, BA Smith-Franklin, RA Rasmussen, ...
Transfusion clinique et biologique 8 (4), 350-358, 2001
Neutralizing antibodies as a potential secondary protective mechanism during chronic SHIV infection in CD8+ T-cell-depleted macaques
RA Rasmussen, R Hofmann-Lehmann, PL Li, J Vlasak, JE Schmitz, ...
Aids 16 (6), 829-838, 2002
Isolation and characterization of IgG1 with asymmetrical Fc glycosylation
S Ha, Y Ou, J Vlasak, Y Li, S Wang, K Vo, Y Du, A Mach, Y Fang, N Zhang
Glycobiology 21 (8), 1087-1096, 2011
DNA prime/protein boost vaccine strategy in neonatal macaques against simian human immunodeficiency virus
RA Rasmussen, R Hofmann‐Lehmann, DC Montefiori, PL Li, V Liska, ...
Journal of medical primatology 31 (1), 40-60, 2002
Passive immunization against oral AIDS virus transmission: An approach to prevent mother‐to‐infant HIV‐1 transmission?
R Hofmann‐Lehmann, RA Rasmussen, J Vlasak, BA Smith, TW Baba, ...
Journal of medical primatology 30 (4), 190-196, 2001
Neutralization of diverse human cytomegalovirus strains conferred by antibodies targeting viral gH/gL/pUL128-131 pentameric complex
S Ha, F Li, MC Troutman, DC Freed, A Tang, JW Loughney, D Wang, ...
Journal of virology 91 (7), e02033-16, 2017
Separation of post-translational modifications in monoclonal antibodies by exploiting subtle conformational changes under mildly acidic conditions
S Wang, R Ionescu, N Peekhaus, J Leung, S Ha, J Vlasak
Journal of Chromatography A 1217 (42), 6496-6502, 2010
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