| Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome FA Sharp, D Ruane, B Claass, E Creagh, J Harris, P Malyala, M Singh, ... Proceedings of the National Academy of Sciences 106 (3), 870-875, 2009 | 650 | 2009 |
| Functional variants in the LRRK2 gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease KY Hui, H Fernandez-Hernandez, J Hu, A Schaffner, N Pankratz, NY Hsu, ... Science translational medicine 10 (423), eaai7795, 2018 | 343 | 2018 |
| IBD across the age spectrum—is it the same disease? J Ruel, D Ruane, S Mehandru, C Gower-Rousseau, JF Colombel Nature reviews Gastroenterology & hepatology 11 (2), 88-98, 2014 | 276 | 2014 |
| Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract D Ruane, L Brane, BS Reis, C Cheong, J Poles, Y Do, H Zhu, K Velinzon, ... Journal of Experimental Medicine 210 (9), 1871-1888, 2013 | 144 | 2013 |
| The Role of CD103+ Dendritic Cells in the Intestinal Mucosal Immune System DT Ruane, EC Lavelle Frontiers in immunology 2, 25, 2011 | 107 | 2011 |
| Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses D Ruane, A Chorny, H Lee, J Faith, G Pandey, M Shan, N Simchoni, ... Journal of Experimental Medicine 213 (1), 53-73, 2016 | 105 | 2016 |
| Classical Flt3L-dependent dendritic cells control immunity to protein vaccine N Anandasabapathy, R Feder, S Mollah, SW Tse, MP Longhi, ... Journal of Experimental Medicine 211 (9), 1875-1891, 2014 | 105 | 2014 |
| A new synthetic TLR4 agonist, GLA, allows dendritic cells targeted with antigen to elicit Th1 T‐cell immunity in vivo A Pantel, C Cheong, D Dandamudi, E Shrestha, S Mehandru, L Brane, ... European journal of immunology 42 (1), 101-109, 2012 | 96 | 2012 |
| Alveolar macrophages contribute to respiratory tolerance by inducing FoxP3 expression in naive T cells MM Coleman, D Ruane, B Moran, PJ Dunne, J Keane, KHG Mills American journal of respiratory cell and molecular biology 48 (6), 773-780, 2013 | 89 | 2013 |
| Phenotype and function of nasal dendritic cells H Lee, D Ruane, K Law, Y Ho, A Garg, A Rahman, D Esterházy, ... Mucosal immunology 8 (5), 1083-1098, 2015 | 72 | 2015 |
| A dendritic cell targeted vaccine induces long-term HIV-specific immunity within the gastrointestinal tract D Ruane, Y Do, L Brane, A Garg, L Bozzacco, T Kraus, M Caskey, ... Mucosal immunology 9 (5), 1340-1352, 2016 | 25 | 2016 |
| IL-36 cytokines imprint a colitogenic phenotype on CD4+ T helper cells G Leon, YEH Santana, N Irwin, E Giannoudaki, S O'Neill, I Csizmadia, ... Mucosal Immunology 15 (3), 491-503, 2022 | 13 | 2022 |
| Systemic redox status associates with disease activity and clinical phenotypes in Inflammatory Bowel Disease S Geertsema, AR Bourgonje, R Gacesa, RR Fagundes, LM Spekhorst, ... JOURNAL OF CROHNS & COLITIS 18, I577-+, 2024 | | 2024 |
| P241 Systemic redox status associates with disease activity and clinical phenotypes in Inflammatory Bowel Disease S Geertsema, AR Bourgonje, R Gacesa, RR Fagundes, LM Spekhorst, ... Journal of Crohn's and Colitis 18 (Supplement_1), i584-i586, 2024 | | 2024 |
| OP23 Guselkumab induction restores intestinal immune homeostasis and promotes epithelial repair in moderately to severely active Ulcerative Colitis S Sridhar, A Hart, S Venkat, D Ruane, D Horowitz, T Lee, D Waterworth, ... Journal of Crohn's and Colitis 18 (Supplement_1), i41-i41, 2024 | | 2024 |
| 77 JNJ-77242113 treatment induces strong systemic pharmacodynamic response versus placebo in patients with plaque psoriasis: Results from the phase 2, FRONTIER 1 study A Pinter, K Eyerich, A Paller, A Kannan, D Strawn, D Horowitz, S Bhagat, ... Journal of Investigative Dermatology 143 (11), S345, 2023 | | 2023 |
| Conditioning of lung dendritic cells by dietary vitamin A and the gastrointestinal microbiota D Ruane, P Manzanillo, H Zhang, L Diehl, J Zeng, N Kljavin, W Sandoval, ... EUROPEAN JOURNAL OF IMMUNOLOGY 46, 774-774, 2016 | | 2016 |
| Mo1924 A Dendritic Cell Targeted Vaccine Induces Long Term HIV-Specific Immune Responses Within the Gastrointestinal Tract S Mehandru, Y Do, D Ruane, L Brane, A Garg, L Bozzacco, M Caskey, ... Gastroenterology 150 (4), S817, 2016 | | 2016 |
| Mo1771 Microbiota Regulate Lung Dendritic Cells Ability to Induce IgA Class Switch Recombination and Generate Protective Gastrointestinal Immune Responsesα D Ruane, A Chorny, M Shan, G Pandey, A Rahman, A Garg, A Cerutti, ... Gastroenterology 148 (4), S-707-S-708, 2015 | | 2015 |
| Subcutaneous immunization to HIV gag is potentiated by Flt3L and develops through classical rather than migratory dendritic cells N Anandasabapathy, R Feder, MP Longhi, S Mehandru, S Mollah, ... JOURNAL OF INVESTIGATIVE DERMATOLOGY 133, S14-S14, 2013 | | 2013 |
