| Motivational activation: a unifying hypothesis of orexin/hypocretin function SV Mahler, DE Moorman, RJ Smith, MH James, G Aston-Jones Nature Neuroscience 17 (10), 1298-1303, 2014 | 359 | 2014 |
| Differential roles of medial prefrontal subregions in the regulation of drug seeking DE Moorman, MH James, EM McGlinchey, G Aston-Jones Brain research 1628, 130-146, 2015 | 262 | 2015 |
| A Decade of Orexin/Hypocretin and Addiction: Where Are We Now? MH James, SV Mahler, DE Moorman, G Aston-Jones Behavioral Neuroscience of Orexin/Hypocretin, 247-281, 2017 | 188 | 2017 |
| Increased number and activity of a lateral subpopulation of hypothalamic orexin/hypocretin neurons underlies the expression of an addicted state in rats MH James, CM Stopper, BA Zimmer, NE Koll, HE Bowrey, G Aston-Jones Biological psychiatry 85 (11), 925-935, 2019 | 174 | 2019 |
| Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine-Dependent Manner to Drive Cued Reinstatement of Cocaine Seeking EM McGlinchey, MH James, SV Mahler, C Pantazis, G Aston-Jones Journal of Neuroscience 36 (33), 8700-8711, 2016 | 155 | 2016 |
| Orexin-1 receptor signalling within the ventral tegmental area, but not the paraventricular thalamus, is critical to regulating cue-induced reinstatement of cocaine-seeking MH James, JL Charnley, EM Levi, E Jones, JW Yeoh, DW Smith, ... International Journal of Neuropsychopharmacology 14 (5), 684-690, 2011 | 152 | 2011 |
| Cocaine-and amphetamine-regulated transcript (CART) signaling within the paraventricular thalamus modulates cocaine-seeking behaviour MH James, JL Charnley, E Jones, EM Levi, JW Yeoh, JR Flynn, DW Smith, ... PLoS One 5 (9), e12980, 2010 | 131 | 2010 |
| Role of the orexin/hypocretin system in stress-related psychiatric disorders MH James, EJ Campbell, CV Dayas Behavioral Neuroscience of Orexin/Hypocretin, 197-219, 2017 | 110 | 2017 |
| Orexin antagonists for neuropsychiatric disease: progress and potential pitfalls JW Yeoh, EJ Campbell, MH James, BA Graham, CV Dayas Frontiers in neuroscience 8, 36, 2014 | 96 | 2014 |
| Orexin/hypocretin-1 receptor antagonism reduces ethanol self-administration and reinstatement selectively in highly-motivated rats DE Moorman, MH James, EA Kilroy, G Aston-Jones Brain Research 1654, 34-42, 2017 | 89 | 2017 |
| Propensity to ‘relapse’following exposure to cocaine cues is associated with the recruitment of specific thalamic and epithalamic nuclei MH James, JL Charnley, JR Flynn, DW Smith, CV Dayas Neuroscience 199, 235-242, 2011 | 89 | 2011 |
| Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats MH James, EJ Campbell, FR Walker, DW Smith, HN Richardson, ... Frontiers in behavioral neuroscience 8, 244, 2014 | 78 | 2014 |
| Intermittent self‐administration of fentanyl induces a multifaceted addiction state associated with persistent changes in the orexin system JE Fragale, MH James, G Aston‐Jones Addiction biology 26 (3), e12946, 2021 | 73 | 2021 |
| Orexin/hypocretin neuron activation is correlated with alcohol seeking and preference in a topographically specific manner DE Moorman, MH James, EA Kilroy, G Aston‐Jones European Journal of Neuroscience 43 (5), 710-720, 2016 | 68 | 2016 |
| The role of orexin-1 receptor signaling in demand for the opioid fentanyl. JE Fragale, CB Pantazis, MH James, G Aston-Jones Neuropsychopharmacology 44 (10), 1690-1697, 2019 | 67 | 2019 |
| What about me...? The PVT: A role for the paraventricular thalamus (PVT) in drug-seeking behaviour. MH James, CV Dayas Frontiers in Behavioral Neuroscience 7, 18, 2013 | 63 | 2013 |
| Cocaine potentiates excitatory drive in the perifornical/lateral hypothalamus JW Yeoh, MH James, P Jobling, JS Bains, BA Graham, CV Dayas The Journal of Physiology 590 (16), 3677-3689, 2012 | 62 | 2012 |
| Sex differences in demand for highly palatable foods: role of the orexin system LR Freeman, BS Bentzley, MH James, G Aston-Jones International Journal of Neuropsychopharmacology 24 (1), 54-63, 2021 | 58 | 2021 |
| Demand elasticity predicts addiction endophenotypes and the therapeutic efficacy of an orexin/hypocretin‐1 receptor antagonist in rats MH James, HE Bowrey, CM Stopper, G Aston‐Jones European Journal of Neuroscience 50 (3), 2602-2612, 2019 | 57 | 2019 |
| Repurposing the dual orexin receptor antagonist suvorexant for the treatment of opioid use disorder: why sleep on this any longer? MH James, JE Fragale, RN Aurora, NA Cooperman, DD Langleben, ... Neuropsychopharmacology 45 (5), 717-719, 2020 | 52 | 2020 |
Gary Aston-JonesDirector, Brain Health Institute, Rutgers UniversityVerified email at rutgers.edu
