The complexity of p53 stabilization and activation MF Lavin, N Gueven Cell Death & Differentiation 13 (6), 941-950, 2006 | 903 | 2006 |
ATM signaling and genomic stability in response to DNA damage MF Lavin, G Birrell, P Chen, S Kozlov, S Scott, N Gueven Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 569 (1 …, 2005 | 287 | 2005 |
Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage A Suraweera, OJ Becherel, P Chen, N Rundle, R Woods, J Nakamura, ... The Journal of cell biology 177 (6), 969-979, 2007 | 220 | 2007 |
Aprataxin, a novel protein that protects against genotoxic stress N Gueven, OJ Becherel, AW Kijas, P Chen, O Howe, JH Rudolph, R Gatti, ... Human molecular genetics 13 (10), 1081-1093, 2004 | 213 | 2004 |
NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels RH Haefeli, M Erb, AC Gemperli, D Robay, I Courdier Fruh, C Anklin, ... PloS one 6 (3), e17963, 2011 | 211 | 2011 |
Zebrafish—on the move towards ophthalmological research J Chhetri, G Jacobson, N Gueven Eye 28 (4), 367-380, 2014 | 184 | 2014 |
Current and potential therapeutic strategies for the treatment of ataxia-telangiectasia MF Lavin, N Gueven, S Bottle, RA Gatti British medical bulletin 81 (1), 129-147, 2007 | 175 | 2007 |
Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM H Beamish, P Kedar, H Kaneko, P Chen, T Fukao, C Peng, S Beresten, ... Journal of Biological Chemistry 277 (34), 30515-30523, 2002 | 163 | 2002 |
Opioid analgesia and opioid-induced adverse effects: a review AK Paul, CM Smith, M Rahmatullah, V Nissapatorn, P Wilairatana, ... Pharmaceuticals 14 (11), 1091, 2021 | 151 | 2021 |
The underlying cellular mechanism of fibrosis. HP Rodemann, A Binder, A Burger, N GÜVEN, H LÖFFLER, M Bamberg Kidney International Supplement, 1996 | 137 | 1996 |
Fucoidan extracts ameliorate acute colitis QY Lean, RD Eri, JH Fitton, RP Patel, N Gueven PloS one 10 (6), e0128453, 2015 | 135 | 2015 |
ATP activates ataxia-telangiectasia mutated (ATM) in vitro: importance of autophosphorylation S Kozlov, N Gueven, K Keating, J Ramsay, MF Lavin Journal of Biological Chemistry 278 (11), 9309-9317, 2003 | 135 | 2003 |
Idebenone protects against retinal damage and loss of vision in a mouse model of Leber’s hereditary optic neuropathy FD Heitz, M Erb, C Anklin, D Robay, V Pernet, N Gueven Public Library of Science 7 (9), e45182, 2012 | 129 | 2012 |
Border between natural product and drug: comparison of the related benzoquinones idebenone and coenzyme Q10 N Gueven, K Woolley, J Smith Redox biology 4, 289-295, 2015 | 122 | 2015 |
Features of idebenone and related short-chain quinones that rescue ATP levels under conditions of impaired mitochondrial complex I M Erb, B Hoffmann-Enger, H Deppe, M Soeberdt, RH Haefeli, C Rummey, ... PloS one 7 (4), e36153, 2012 | 117 | 2012 |
ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control M Gatei, B Jakob, P Chen, AW Kijas, OJ Becherel, N Gueven, G Birrell, ... Journal of Biological Chemistry 286 (36), 31542-31556, 2011 | 105 | 2011 |
Dramatic extension of tumor latency and correction of neurobehavioral phenotype in Atm-mutant mice with a nitroxide antioxidant N Gueven, J Luff, C Peng, K Hosokawa, SE Bottle, MF Lavin Free Radical Biology and Medicine 41 (6), 992-1000, 2006 | 89 | 2006 |
ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1 AW Kijas, YC Lim, E Bolderson, K Cerosaletti, M Gatei, B Jakob, F Tobias, ... Nucleic acids research 43 (17), 8352-8367, 2015 | 83 | 2015 |
Live cell imaging of heavy-ion-induced radiation responses by beamline microscopy B Jakob, JH Rudolph, N Gueven, MF Lavin, G Taucher-Scholz Radiation research 163 (6), 681-690, 2005 | 83 | 2005 |
Functional consequences of sequence alterations in the ATM gene MF Lavin, S Scott, N Gueven, S Kozlov, C Peng, P Chen DNA repair 3 (8-9), 1197-1205, 2004 | 81 | 2004 |