Lisa Mielke, PhD
Lisa Mielke, PhD
Laboratory Head, Olivia Newton-John Cancer Research Institute
Verified email at
TitleCited byYear
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
SL Masters, A Dunne, SL Subramanian, RL Hull, GM Tannahill, FA Sharp, ...
Nature immunology 11 (10), 897, 2010
The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells
A Vasanthakumar, K Moro, A Xin, Y Liao, R Gloury, S Kawamoto, ...
Nature immunology 16 (3), 276, 2015
IL‐17‐producing γδ T cells and innate lymphoid cells
CE Sutton, LA Mielke, KHG Mills
European journal of immunology 42 (9), 2221-2231, 2012
General nature of the STAT3-activated anti-inflammatory response
KC El Kasmi, J Holst, M Coffre, L Mielke, A De Pauw, N Lhocine, ...
The Journal of Immunology 177 (11), 7880-7888, 2006
The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway
LC Rankin, JR Groom, M Chopin, MJ Herold, JA Walker, LA Mielke, ...
Nature immunology 14 (4), 389, 2013
Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation
LA Mielke, SA Jones, M Raverdeau, R Higgs, A Stefanska, JR Groom, ...
Journal of Experimental Medicine 210 (6), 1117-1124, 2013
T-box transcription factors combine with the cytokines TGF-β and IL-15 to control tissue-resident memory T cell fate
LK Mackay, E Wynne-Jones, D Freestone, DG Pellicci, LA Mielke, ...
Immunity 43 (6), 1101-1111, 2015
The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability
JJ Babon, EJ McManus, S Yao, DP DeSouza, LA Mielke, NS Sprigg, ...
Molecular cell 22 (2), 205-216, 2006
Nfil3 is required for the development of all innate lymphoid cell subsets
C Seillet, LC Rankin, JR Groom, LA Mielke, J Tellier, M Chopin, ...
Journal of Experimental Medicine 211 (9), 1733-1740, 2014
The comparative roles of suppressor of cytokine signaling-1 and-3 in the inhibition and desensitization of cytokine signaling
S Wormald, JG Zhang, DL Krebs, LA Mielke, J Silver, WS Alexander, ...
Journal of Biological Chemistry 281 (16), 11135-11143, 2006
Complementarity and redundancy of IL-22-producing innate lymphoid cells
LC Rankin, MJH Girard-Madoux, C Seillet, LA Mielke, Y Kerdiles, A Fenis, ...
Nature immunology 17 (2), 179, 2016
TCF-1 controls ILC2 and NKp46+ RORγt+ innate lymphocyte differentiation and protection in intestinal inflammation
LA Mielke, JR Groom, LC Rankin, C Seillet, F Masson, T Putoczki, ...
The Journal of Immunology 191 (8), 4383-4391, 2013
Tpl2 kinase regulates T cell interferon-γ production and host resistance to Toxoplasma gondii
WT Watford, BD Hissong, LR Durant, H Yamane, LM Muul, Y Kanno, ...
Journal of Experimental Medicine 205 (12), 2803-2812, 2008
Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells
P Sathe, RB Delconte, F Souza-Fonseca-Guimaraes, C Seillet, M Chopin, ...
Nature communications 5, 4539, 2014
Tumor progression locus 2 (Map3k8) is critical for host defense against Listeria monocytogenes and IL-1β production
LA Mielke, KL Elkins, L Wei, R Starr, PN Tsichlis, JJ O'Shea, WT Watford
The Journal of Immunology 183 (12), 7984-7993, 2009
Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia
BT Kile, AD Panopoulos, RA Stirzaker, DF Hacking, LH Tahtamouni, ...
Blood 110 (7), 2371-2380, 2007
Development of hydrocephalus in mice lacking SOCS7
DL Krebs, D Metcalf, TD Merson, AK Voss, T Thomas, JG Zhang, S Rakar, ...
Proceedings of the National Academy of Sciences 101 (43), 15446-15451, 2004
Regulation of interleukin‐1β by interferon‐γ is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin‐17 production
SL Masters, LA Mielke, AL Cornish, CE Sutton, J O'donnell, LH Cengia, ...
EMBO reports 11 (8), 640-646, 2010
The helix-loop-helix protein ID2 governs NK cell fate by tuning their sensitivity to interleukin-15
RB Delconte, W Shi, P Sathe, T Ushiki, C Seillet, M Minnich, TB Kolesnik, ...
Immunity 44 (1), 103-115, 2016
Deciphering the innate lymphoid cell transcriptional program
C Seillet, LA Mielke, DB Amann-Zalcenstein, S Su, J Gao, FF Almeida, ...
Cell reports 17 (2), 436-447, 2016
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