David T. Riglar
David T. Riglar
Harvard Medical School
Verified email at hms.harvard.edu
TitleCited byYear
Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte
DT Riglar, D Richard, DW Wilson, MJ Boyle, C Dekiwadia, L Turnbull, ...
Cell host & microbe 9 (1), 9-20, 2011
2802011
Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development
MJ Boyle, DW Wilson, JS Richards, DT Riglar, KKA Tetteh, DJ Conway, ...
Proceedings of the National Academy of Sciences 107 (32), 14378-14383, 2010
2062010
Interaction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites
D Richard, CA MacRaild, DT Riglar, JA Chan, M Foley, J Baum, SA Ralph, ...
Journal of Biological Chemistry 285 (19), 14815-14822, 2010
2032010
Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax
JI Fletcher, S Meusburger, CJ Hawkins, DT Riglar, EF Lee, WD Fairlie, ...
Proceedings of the National Academy of Sciences 105 (47), 18081-18087, 2008
1792008
An EGF-like protein forms a complex with PfRh5 and is required for invasion of human erythrocytes by Plasmodium falciparum
L Chen, S Lopaticki, DT Riglar, C Dekiwadia, AD Uboldi, WH Tham, ...
PLoS pathogens 7 (9), e1002199, 2011
1032011
Biosynthesis, localization, and macromolecular arrangement of the Plasmodium falciparum translocon of exported proteins (PTEX)
HE Bullen, SC Charnaud, M Kalanon, DT Riglar, C Dekiwadia, ...
Journal of Biological Chemistry 287 (11), 7871-7884, 2012
972012
Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation
DT Riglar, TW Giessen, M Baym, SJ Kerns, MJ Niederhuber, RT Bronson, ...
Nature biotechnology 35 (7), 653, 2017
802017
Spatial localisation of actin filaments across developmental stages of the malaria parasite
F Angrisano, DT Riglar, A Sturm, JC Volz, MJ Delves, ES Zuccala, ...
PloS one 7 (2), e32188, 2012
702012
Spatial association with PTEX complexes defines regions for effector export into Plasmodium falciparum-infected erythrocytes
DT Riglar, KL Rogers, E Hanssen, L Turnbull, HE Bullen, SC Charnaud, ...
Nature communications 4, 1415, 2013
622013
Membrane-wrapping contributions to malaria parasite invasion of the human erythrocyte
S Dasgupta, T Auth, NS Gov, TJ Satchwell, E Hanssen, ES Zuccala, ...
Biophysical journal 107 (1), 43-54, 2014
472014
Plasmodium falciparum merozoite invasion is inhibited by antibodies that target the PfRh2a and b binding domains
T Triglia, L Chen, S Lopaticki, C Dekiwadia, DT Riglar, AN Hodder, ...
PLoS pathogens 7 (6), e1002075, 2011
462011
Vaccination with conserved regions of erythrocyte-binding antigens induces neutralizing antibodies against multiple strains of Plasmodium falciparum
J Healer, JK Thompson, DT Riglar, DW Wilson, YHC Chiu, K Miura, ...
PloS one 8 (9), e72504, 2013
432013
Electron tomography of Plasmodium falciparum merozoites reveals core cellular events that underpin erythrocyte invasion
E Hanssen, C Dekiwadia, DT Riglar, M Rug, L Lemgruber, AF Cowman, ...
Cellular microbiology 15 (9), 1457-1472, 2013
392013
Engineering bacteria for diagnostic and therapeutic applications
DT Riglar, PA Silver
Nature Reviews Microbiology 16 (4), 214, 2018
372018
Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1
W Wong, CT Skau, DS Marapana, E Hanssen, NL Taylor, DT Riglar, ...
Proceedings of the National Academy of Sciences 108 (24), 9869-9874, 2011
362011
Subcompartmentalisation of proteins in the rhoptries correlates with ordered events of erythrocyte invasion by the blood stage malaria parasite
ES Zuccala, AM Gout, C Dekiwadia, DS Marapana, F Angrisano, ...
PloS one 7 (9), e46160, 2012
342012
Cryo-electron tomography reveals four-membrane architecture of the Plasmodium apicoplast
L Lemgruber, M Kudryashev, C Dekiwadia, DT Riglar, J Baum, ...
Malaria journal 12 (1), 25, 2013
332013
Plasmodium falciparum coronin organizes arrays of parallel actin filaments potentially guiding directional motility in invasive malaria parasites
MA Olshina, F Angrisano, DS Marapana, DT Riglar, K Bane, W Wong, ...
Malaria journal 14 (1), 280, 2015
202015
Localisation-based imaging of malarial antigens during erythrocyte entry reaffirms a role for AMA1 but not MTRAP in invasion
DT Riglar, L Whitehead, AF Cowman, KL Rogers, J Baum
J Cell Sci 129 (1), 228-242, 2016
142016
Static and Dynamic Imaging of Erythrocyte Invasion and Early Intra-erythrocytic Development in Plasmodium falciparum
DT Riglar, J Baum
Malaria, 269-280, 2012
42012
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Articles 1–20