| High-resolution X-ray structure of an early intermediate in the bacteriorhodopsin photocycle K Edman, P Nollert, A Royant, H Belrhali, E Pebay-Peyroula, J Hajdu, ... Nature 401 (6755), 822-826, 1999 | 425 | 1999 |
| X-ray structure of sensory rhodopsin II at 2.1-Å resolution A Royant, P Nollert, K Edman, R Neutze, EM Landau, E Pebay-Peyroula, ... Proceedings of the National Academy of Sciences 98 (18), 10131-10136, 2001 | 371 | 2001 |
| Helix deformation is coupled to vectorial proton transport in the photocycle of bacteriorhodopsin A Royant, K Edman, T Ursby, E Pebay-Peyroula, EM Landau, R Neutze Nature 406 (6796), 645-648, 2000 | 309 | 2000 |
| Bacteriorhodopsin: a high-resolution structural view of vectorial proton transport R Neutze, E Pebay-Peyroula, K Edman, A Royant, J Navarro, EM Landau Biochimica et Biophysica Acta (BBA)-Biomembranes 1565 (2), 144-167, 2002 | 290 | 2002 |
| Structural insight into allosteric modulation of protease-activated receptor 2 RKY Cheng, C Fiez-Vandal, O Schlenker, K Edman, B Aggeler, DG Brown, ... Nature 545 (7652), 112-115, 2017 | 240 | 2017 |
| X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate RC Wilmouth, K Edman, R Neutze, PA Wright, IJ Clifton, TR Schneider, ... Nature structural biology 8 (8), 689-694, 2001 | 141 | 2001 |
| Ligand binding mechanism in steroid receptors: from conserved plasticity to differential evolutionary constraints K Edman, A Hosseini, MK Bjursell, A Aagaard, L Wissler, A Gunnarsson, ... Structure 23 (12), 2280-2290, 2015 | 109 | 2015 |
| Analyzing protein functions in four dimensions J Hajdu, R Neutze, T Sjögren, K Edman, A Szöke, RC Wilmouth, ... Nature structural biology 7 (11), 1006-1012, 2000 | 102 | 2000 |
| Deformation of helix C in the low temperature L-intermediate of bacteriorhodopsin K Edman, A Royant, G Larsson, F Jacobson, T Taylor, D van der Spoel, ... Journal of Biological Chemistry 279 (3), 2147-2158, 2004 | 98 | 2004 |
| Novel prostaglandin D synthase inhibitors generated by fragment-based drug design M Hohwy, L Spadola, B Lundquist, P Hawtin, J Dahmén, I Groth-Clausen, ... Journal of medicinal chemistry 51 (7), 2178-2186, 2008 | 83 | 2008 |
| Early structural rearrangements in the photocycle of an integral membrane sensory receptor K Edman, A Royant, P Nollert, CA Maxwell, E Pebay-Peyroula, J Navarro, ... Structure 10 (4), 473-482, 2002 | 74 | 2002 |
| Discovery of a novel oral glucocorticoid receptor modulator (AZD9567) with improved side effect profile L Ripa, K Edman, M Dearman, G Edenro, R Hendrickx, V Ullah, ... Journal of Medicinal Chemistry 61 (5), 1785-1799, 2018 | 66 | 2018 |
| Cathepsin C inhibitors: property optimization and identification of a clinical candidate M Furber, AK Tiden, P Gardiner, A Mete, R Ford, I Millichip, L Stein, ... Journal of Medicinal Chemistry 57 (6), 2357-2367, 2014 | 65 | 2014 |
| Selective nonsteroidal glucocorticoid receptor modulators for the inhaled treatment of pulmonary diseases M Hemmerling, S Nilsson, K Edman, S Eirefelt, W Russell, R Hendrickx, ... Journal of Medicinal Chemistry 60 (20), 8591-8605, 2017 | 54 | 2017 |
| Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion K Bamberg, U Johansson, K Edman, L William-Olsson, S Myhre, ... PLoS One 13 (2), e0193380, 2018 | 51 | 2018 |
| Chemical Compounds 572 M Berger, J Dahmén, K Edman, A Eriksson, B Gabos, T Hansson, ... US Patent App. 13/429,177, 2012 | 51 | 2012 |
| The discovery of MMP7 inhibitors exploiting a novel selectivity trigger K Edman, M Furber, P Hemsley, C Johansson, G Pairaudeau, J Petersen, ... ChemMedChem 6 (5), 769-773, 2011 | 47 | 2011 |
| Spectroscopic Characterization of Bacteriorhodopsin's L‐intermediate in 3D Crystals Cooled to 170 K¶ A Royant, K Edman, T Ursby, E Pebay‐Peyroula, EM Landau, R Neutze Photochemistry and photobiology 74 (6), 794-804, 2001 | 35 | 2001 |
| The discovery of potent and selective non-steroidal glucocorticoid receptor modulators, suitable for inhalation K Edman, R Ahlgren, M Bengtsson, H Bladh, S Bäckström, J Dahmén, ... Bioorganic & medicinal chemistry letters 24 (11), 2571-2577, 2014 | 33 | 2014 |
| Dynamic allosteric communication pathway directing differential activation of the glucocorticoid receptor C Köhler, G Carlström, A Gunnarsson, U Weininger, S Tångefjord, V Ullah, ... Science Advances 6 (29), eabb5277, 2020 | 32 | 2020 |
Richard NeutzeProfessor of Biochemistry, University of GothenburgVerified email at gu.se
