Targeting Toll-like receptors with small molecule agents X Wang, C Smith, H Yin Chemical Society Reviews 42 (12), 4859-4866, 2013 | 121 | 2013 |
Engineering enzymes for noncanonical amino acid synthesis PJ Almhjell, CE Boville, FH Arnold Chemical Society Reviews 47 (24), 8980-8997, 2018 | 106 | 2018 |
Non-steroidal anti-inflammatory drugs are caspase inhibitors CE Smith, S Soti, TA Jones, A Nakagawa, D Xue, H Yin Cell chemical biology 24 (3), 281-292, 2017 | 83 | 2017 |
Lipidated cyclic γ-AApeptides display both antimicrobial and anti-inflammatory activity Y Li, C Smith, H Wu, S Padhee, N Manoj, J Cardiello, Q Qiao, C Cao, ... ACS chemical biology 9 (1), 211-217, 2014 | 81 | 2014 |
Scalable continuous evolution for the generation of diverse enzyme variants encompassing promiscuous activities G Rix, EJ Watkins-Dulaney, PJ Almhjell, CE Boville, FH Arnold, CC Liu Nature Communications 11 (1), 5644, 2020 | 80 | 2020 |
Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain X Wang, PM Grace, MN Pham, K Cheng, KA Strand, C Smith, J Li, ... The FASEB Journal 27 (7), 2713, 2013 | 73 | 2013 |
Engineered biosynthesis of β‐alkyl tryptophan analogues CE Boville, RA Scheele, P Koch, S Brinkmann‐Chen, AR Buller, ... Angewandte Chemie 130 (45), 14980-14984, 2018 | 60 | 2018 |
Improved Synthesis of 4-Cyanotryptophan and Other Tryptophan Analogues in Aqueous Solvent Using Variants of TrpB from Thermotoga maritima CE Boville, DK Romney, PJ Almhjell, M Sieben, FH Arnold The Journal of organic chemistry 83 (14), 7447-7452, 2018 | 56 | 2018 |
Short Antimicrobial Lipo‐α/γ‐AA Hybrid Peptides Y Li, C Smith, H Wu, P Teng, Y Shi, S Padhee, T Jones, AM Nguyen, ... ChemBioChem 15 (15), 2275-2280, 2014 | 52 | 2014 |
Saccharin derivatives as inhibitors of interferon-mediated inflammation A Csakai, C Smith, E Davis, A Martinko, S Coulup, H Yin Journal of Medicinal Chemistry 57 (12), 5348-5355, 2014 | 38 | 2014 |
The Development of Antimicrobial α‐AApeptides that Suppress Proinflammatory Immune Responses S Padhee, C Smith, H Wu, Y Li, N Manoj, Q Qiao, Z Khan, C Cao, H Yin, ... ChemBioChem 15 (5), 688-694, 2014 | 25 | 2014 |
Caspases come together over LPS C Smith, X Wang, H Yin Trends in immunology 36 (2), 59-61, 2015 | 22 | 2015 |
Biocatalytic synthesis of α-amino ketones SW Chun, ARH Narayan Synlett 30 (11), 1269-1274, 2019 | 21 | 2019 |
Repositioning antimicrobial agent pentamidine as a disruptor of the lateral interactions of transmembrane domain 5 of EBV latent membrane protein 1 X Wang, Z Fiorini, C Smith, Y Zhang, J Li, LR Watkins, H Yin Public Library of Science 7 (10), e47703, 2012 | 10 | 2012 |
Beta-substituted non-canonical amino acids CE Boville, S Brinkmann-Chen, AR Buller, DK Romney, CK Prier, P Koch, ... US Patent 10,612,056, 2020 | 4 | 2020 |
Method for the synthesis of tryptophan analogs in aqueous solvents at reduced temperatures CE Boville, DK Romney, PJ Almhjell, MM Sieben US Patent 10,752,927, 2020 | 1 | 2020 |
Methods and enzyme catalysts for the synthesis of non-canonical amino acids CE Boville, S Brinkmann-Chen, AR Buller, DK Romney, CK Prier, P Koch, ... US Patent App. 17/556,555, 2022 | | 2022 |
Methods and enzyme catalysts for the synthesis of non-canonical amino acids CE Boville, S Brinkmann-Chen, AR Buller, DK Romney, CK Prier, P Koch, ... US Patent 11,279,959, 2022 | | 2022 |
Characterization of Chemical Probes for Therapeutic Intervention of Innate Immune Signaling CE Boville University of Colorado, 2017 | | 2017 |
Angewandte CE Boville, RA Scheele, P Koch, S Brinkmann-Chen, AR Buller, ... | | |