The TGR5 receptor mediates bile acid–induced itch and analgesia F Alemi, E Kwon, DP Poole, TM Lieu, V Lyo, F Cattaruzza, F Cevikbas, ... The Journal of clinical investigation 123 (4), 1513-1530, 2013 | 393 | 2013 |
The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice TM Lieu, G Jayaweera, P Zhao, DP Poole, D Jensen, M Grace, P McIntyre, ... Gastroenterology 147 (6), 1417-1428, 2014 | 226 | 2014 |
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief DD Jensen, TM Lieu, ML Halls, NA Veldhuis, WL Imlach, QN Mai, ... Science Translational Medicine 9 (392), eaal3447, 2017 | 192 | 2017 |
Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4 P Zhao, TM Lieu, N Barlow, M Metcalf, NA Veldhuis, DD Jensen, M Kocan, ... Journal of Biological Chemistry 289 (39), 27215-27234, 2014 | 182 | 2014 |
G protein-coupled receptors: dynamic machines for signaling pain and itch P Geppetti, NA Veldhuis, TM Lieu, NW Bunnett Neuron 88 (4), 635-649, 2015 | 171 | 2015 |
Protease-activated receptor 2 (PAR2) protein and transient receptor potential vanilloid 4 (TRPV4) protein coupling is required for sustained inflammatory signaling DP Poole, S Amadesi, NA Veldhuis, FC Abogadie, TM Lieu, W Darby, ... Journal of biological chemistry 288 (8), 5790-5802, 2013 | 167 | 2013 |
Neutrophil elastase activates protease-activated receptor-2 (PAR2) and transient receptor potential vanilloid 4 (TRPV4) to cause inflammation and pain P Zhao, TM Lieu, N Barlow, S Sostegni, S Haerteis, C Korbmacher, ... Journal of Biological Chemistry 290 (22), 13875-13887, 2015 | 166 | 2015 |
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission RE Yarwood, WL Imlach, TM Lieu, NA Veldhuis, DD Jensen, ... Proceedings of the National Academy of Sciences 114 (46), 12309-12314, 2017 | 154 | 2017 |
Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome NN Jimenez-Vargas, LA Pattison, P Zhao, TM Lieu, R Latorre, DD Jensen, ... Proceedings of the National Academy of Sciences 115 (31), E7438-E7447, 2018 | 150 | 2018 |
Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum S Abu‐Hayyeh, C Ovadia, TM Lieu, DD Jensen, J Chambers, PH Dixon, ... Hepatology 63 (4), 1287-1298, 2016 | 145 | 2016 |
TRPV1 induction in airway vagal low-threshold mechanosensory neurons by allergen challenge and neurotrophic factors TM Lieu, AC Myers, S Meeker, BJ Undem American Journal of Physiology-Lung Cellular and Molecular Physiology 302 (9 …, 2012 | 129 | 2012 |
A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain PD Ramírez-García, JS Retamal, P Shenoy, W Imlach, M Sykes, N Truong, ... Nature Nanotechnology 14 (12), 1150-1159, 2019 | 115 | 2019 |
Role of TGR5 (GPBAR1) in liver disease V Keitel, D Häussinger Seminars in liver disease 38 (04), 333-339, 2018 | 84 | 2018 |
Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity J Castro, AM Harrington, TM Lieu, S Garcia-Caraballo, J Maddern, ... JCI insight 4 (20), 2019 | 68 | 2019 |
Neurotrophin and GDNF family ligand receptor expression in vagal sensory nerve subtypes innervating the adult guinea pig respiratory tract TM Lieu, M Kollarik, AC Myers, BJ Undem American Journal of Physiology-Lung Cellular and Molecular Physiology 300 (5 …, 2011 | 58 | 2011 |
GPBA: a GPCR for bile acids and an emerging therapeutic target for disorders of digestion and sensation T Lieu, G Jayaweera, NW Bunnett British journal of pharmacology 171 (5), 1156-1166, 2014 | 55 | 2014 |
The tyrosine kinase inhibitor bafetinib inhibits PAR2‐induced activation of TRPV4 channels in vitro and pain in vivo MS Grace, T Lieu, B Darby, FC Abogadie, N Veldhuis, NW Bunnett, ... British journal of pharmacology 171 (16), 3881-3894, 2014 | 54 | 2014 |
Parainfluenza 3-Induced Cough Hypersensitivity in the Guinea Pig Airways BJU Eric J. Zaccone , TinaMarie Lieu , Yukiko Muroi , Carl Potenzieri ... Plos One, 2016 | 53 | 2016 |
Effects of food components that activate TRPA1 receptors on mucosal ion transport in the mouse intestine LJ Fothergill, B Callaghan, LR Rivera, TM Lieu, DP Poole, HJ Cho, ... Nutrients 8 (10), 623, 2016 | 35 | 2016 |
G-CSF receptor blockade ameliorates arthritic pain and disease MC Lee, JA McCubbin, AD Christensen, DP Poole, P Rajasekhar, ... The Journal of Immunology 198 (9), 3565-3575, 2017 | 33 | 2017 |