Loretta Dorstyn
Loretta Dorstyn
Centre for Cancer Biology, University of South Australia
Verified email at unisa.edu.au - Homepage
Cited by
Cited by
Old, new and emerging functions of caspases
S Shalini, L Dorstyn, S Dawar, S Kumar
Cell Death & Differentiation 22 (4), 526-539, 2015
DRONC, an ecdysone-inducible Drosophila caspase
L Dorstyn, PA Colussi, LM Quinn, H Richardson, S Kumar
Proceedings of the National Academy of Sciences 96 (8), 4307-4312, 1999
The role of cytochrome c in caspase activation in Drosophila melanogaster cells
L Dorstyn, S Read, D Cakouros, JR Huh, BA Hay, S Kumar
The Journal of cell biology 156 (6), 1089-1098, 2002
An essential role for the caspase dronc in developmentally programmed cell death in Drosophila
LM Quinn, L Dorstyn, K Mills, PA Colussi, P Chen, M Coombe, J Abrams, ...
Journal of Biological Chemistry 275 (51), 40416-40424, 2000
A tumor suppressor function for caspase-2
LH Ho, R Taylor, L Dorstyn, D Cakouros, P Bouillet, S Kumar
Proceedings of the National Academy of Sciences 106 (13), 5336-5341, 2009
DECAY, a novel Drosophila caspase related to mammalian caspase-3 and caspase-7
L Dorstyn, SH Read, LM Quinn, H Richardson, S Kumar
Journal of Biological Chemistry 274 (43), 30778-30783, 1999
The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells
L Dorstyn, K Mills, Y Lazebnik, S Kumar
The Journal of Cell Biology 167 (3), 405-410, 2004
Caspase-2 is required for cell death induced by cytoskeletal disruption
LH Ho, SH Read, L Dorstyn, L Lambrusco, S Kumar
Oncogene 27 (24), 3393-3404, 2008
Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2
NJ Foot, HE Dalton, LM Shearwin-Whyatt, L Dorstyn, SS Tan, B Yang, ...
Blood, The Journal of the American Society of Hematology 112 (10), 4268-4275, 2008
Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons
J Howitt, U Putz, J Lackovic, A Doan, L Dorstyn, H Cheng, B Yang, ...
Proceedings of the National Academy of Sciences 106 (36), 15489-15494, 2009
Characterization of the DrosophilaCaspase, DAMM
NL Harvey, T Daish, K Mills, L Dorstyn, LM Quinn, SH Read, ...
Journal of Biological Chemistry 276 (27), 25342-25350, 2001
Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability
L Dorstyn, J Puccini, CH Wilson, S Shalini, M Nicola, S Moore, S Kumar
Cell Death & Differentiation 19 (8), 1288-1298, 2012
Structure of the Drosophila apoptosome at 6.9 resolution
S Yuan, X Yu, M Topf, L Dorstyn, S Kumar, SJ Ludtke, CW Akey
Structure 19 (1), 128-140, 2011
Caspase-2 as a tumour suppressor
J Puccini, L Dorstyn, S Kumar
Cell Death & Differentiation 20 (9), 1133-1139, 2013
Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice
S Shalini, L Dorstyn, C Wilson, J Puccini, L Ho, S Kumar
Cell Death & Differentiation 19 (8), 1370-1380, 2012
Apoptosis methods and protocols
HJM Brady
Humana Press, 2004
New insights into apoptosome structure and function
L Dorstyn, CW Akey, S Kumar
Cell Death & Differentiation 25 (7), 1194-1208, 2018
A biochemical analysis of the activation of the Drosophila caspase DRONC
L Dorstyn, S Kumar
Cell Death & Differentiation 15 (3), 461-470, 2008
Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice
J Puccini, S Shalini, AK Voss, M Gatei, CH Wilson, DK Hiwase, MF Lavin, ...
Proceedings of the National Academy of Sciences 110 (49), 19920-19925, 2013
ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis
JJ Sandow, L Dorstyn, LA O'reilly, M Tailler, S Kumar, A Strasser, ...
Cell Death & Differentiation 21 (3), 475-480, 2014
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