| Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression IS Harris, AE Treloar, S Inoue, M Sasaki, C Gorrini, KC Lee, KY Yung, ... Cancer cell 27 (2), 211-222, 2015 | 913 | 2015 |
| Advances in the molecular genetics of gliomas—implications for classification and therapy G Reifenberger, HG Wirsching, CB Knobbe-Thomsen, M Weller Nature reviews Clinical oncology 14 (7), 434-452, 2017 | 631 | 2017 |
| IDH1 (R132H) mutation increases murine haematopoietic progenitors and alters epigenetics M Sasaki, CB Knobbe, JC Munger, EF Lind, D Brenner, A Brüstle, ... Nature 488 (7413), 656-659, 2012 | 602 | 2012 |
| Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas J Reifenberger, M Wolter, CB Knobbe, B Köhler, A Schönicke, ... British Journal of Dermatology 152 (1), 43-51, 2005 | 519 | 2005 |
| D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function M Sasaki, CB Knobbe, M Itsumi, AJ Elia, IS Harris, IIC Chio, RA Cairns, ... Genes & development 26 (18), 2038-2049, 2012 | 343 | 2012 |
| Genetic alterations and aberrant expression of genes related to the phosphatidyl‐lnositol‐3′‐kinase/protein kinase B (Akt) signal transduction pathway in glioblastomas CB Knobbe, G Reifenberger Brain pathology 13 (4), 507-518, 2003 | 327 | 2003 |
| Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling M Zuckermann, V Hovestadt, CB Knobbe-Thomsen, M Zapatka, ... Nature communications 6 (1), 7391, 2015 | 305 | 2015 |
| Pten signaling in gliomas CB Knobbe, A Merlo, G Reifenberger Neuro-oncology 4 (3), 196-211, 2002 | 284 | 2002 |
| EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma QW Fan, CK Cheng, WC Gustafson, E Charron, P Zipper, RA Wong, ... Cancer cell 24 (4), 438-449, 2013 | 270 | 2013 |
| Mutation analysis of the Ras pathway genes NRAS, HRAS, KRAS and BRAF in glioblastomas CB Knobbe, J Reifenberger, G Reifenberger Acta neuropathologica 108, 467-470, 2004 | 188 | 2004 |
| Frequent alterations of Ras signaling pathway genes in sporadic malignant melanomas J Reifenberger, CB Knobbe, AA Sterzinger, B Blaschke, KW Schulte, ... International journal of cancer 109 (3), 377-384, 2004 | 179 | 2004 |
| Comprehensive analysis of genomic alterations in gliosarcoma and its two tissue components B Actor, JMJL Cobbers, R Büschges, M Wolter, CB Knobbe, ... Genes, Chromosomes and Cancer 34 (4), 416-427, 2002 | 167 | 2002 |
| The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey CB Knobbe, V Lapin, A Suzuki, TW Mak Oncogene 27 (41), 5398-5415, 2008 | 145 | 2008 |
| Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC J Reifenberger, CB Knobbe, M Wolter, B Blaschke, KW Schulte, T Pietsch, ... International journal of cancer 100 (5), 549-556, 2002 | 138 | 2002 |
| The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells A Brüstle, D Brenner, CB Knobbe, PA Lang, C Virtanen, BM Hershenfield, ... The Journal of clinical investigation 122 (12), 4698-4709, 2012 | 137 | 2012 |
| Genetic alteration and expression of the phosphoinositol‐3‐kinase/Akt pathway genes PIK3CA and PIKE in human glioblastomas CB Knobbe, A Trampe‐Kieslich, G Reifenberger Neuropathology and applied neurobiology 31 (5), 486-490, 2005 | 136 | 2005 |
| Glutathione restricts serine metabolism to preserve regulatory T cell function H Kurniawan, DG Franchina, L Guerra, L Bonetti, L Soriano-Baguet, ... Cell metabolism 31 (5), 920-936. e7, 2020 | 123 | 2020 |
| Refined mapping of 1q32 amplicons in malignant gliomas confirms MDM4 as the main amplification target MJ Riemenschneider, CB Knobbe, G Reifenberger International journal of cancer 104 (6), 752-757, 2003 | 117 | 2003 |
| The topoisomerase II inhibitor, genistein, induces G2/M arrest and apoptosis in human malignant glioma cell lines F Schmidt, CB Knobbe, B Frank, H Wolburg, M Weller Oncology reports 19 (4), 1061-1066, 2008 | 112 | 2008 |
| Gliomatosis cerebri: molecular pathology and clinical course U Herrlinger, J Felsberg, W Küker, A Bornemann, L Plasswilm, ... Annals of Neurology: Official Journal of the American Neurological …, 2002 | 97 | 2002 |
