| Cholesterol synthesis AJ Brown, HW Coates, LJ Sharpe Biochemistry of lipids, lipoproteins and membranes, 317-355, 2021 | 73 | 2021 |
| Squalene monooxygenase: a journey to the heart of cholesterol synthesis NK Chua, HW Coates, AJ Brown Progress in lipid research 79, 101033, 2020 | 68 | 2020 |
| A key mammalian cholesterol synthesis enzyme, squalene monooxygenase, is allosterically stabilized by its substrate H Yoshioka, HW Coates, NK Chua, Y Hashimoto, AJ Brown, K Ohgane Proceedings of the National Academy of Sciences 117 (13), 7150-7158, 2020 | 62 | 2020 |
| A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols R Yan, P Cao, W Song, H Qian, X Du, HW Coates, X Zhao, Y Li, S Gao, ... Science 371 (6533), eabb2224, 2021 | 56 | 2021 |
| Post-translational control of the long and winding road to cholesterol LJ Sharpe, HW Coates, AJ Brown Journal of Biological Chemistry 295 (51), 17549-17559, 2020 | 39 | 2020 |
| The mammalian cholesterol synthesis enzyme squalene monooxygenase is proteasomally truncated to a constitutively active form HW Coates, IM Capell-Hattam, AJ Brown Journal of Biological Chemistry 296, 2021 | 22 | 2021 |
| Cholesterol, cancer, and rebooting a treatment for athlete’s foot NK Chua, HW Coates, AJ Brown Science translational medicine 10 (437), eaat3741, 2018 | 14 | 2018 |
| Consulting prostate cancer cohort data uncovers transcriptional control: regulation of the MARCH6 gene HW Coates, NK Chua, AJ Brown Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 11 | 2019 |
| A wolf in sheep's clothing: unmasking the lanosterol-induced degradation of HMG-CoA reductase HW Coates, AJ Brown Journal of Lipid Research 60 (10), 1643-1645, 2019 | 10 | 2019 |
| Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase HW Coates, IM Capell-Hattam, EM Olzomer, X Du, R Farrell, H Yang, ... Elife 12, e82843, 2023 | 8 | 2023 |
| The non catalytic protein ERG28 has a functional role in cholesterol synthesis and is coregulated transcriptionally IM Capell-Hattam, NM Fenton, HW Coates, LJ Sharpe, AJ Brown Journal of Lipid Research 63 (12), 2022 | 8 | 2022 |
| The constitutively active form of a key cholesterol synthesis enzyme is lipid droplet-localized and upregulated in endometrial cancer tissues HW Coates, TB Nguyen, X Du, EM Olzomer, R Farrell, FL Byrne, H Yang, ... Journal of Biological Chemistry 300 (5), 2024 | | 2024 |
| Thesis abstract Substrate-induced activation of the rate-limiting cholesterol synthesis enzyme squalene monooxygenase HW Coates Journal and Proceedings of the Royal Society of New South Wales 156 (part 2 …, 2023 | | 2023 |
| Asters: rising stars in the cholesterol universe HW Coates, AJ Brown Nature Metabolism 5 (1), 16-18, 2023 | | 2023 |
Andrew John BrownProfessor of Biochemistry, University of New South WalesVerified email at unsw.edu.au
