Jacky Y Suen
Jacky Y Suen
Critical Care Research Group, The University of Queensland and The Prince Charles Hospital
Verified email at uq.edu.au - Homepage
Cited by
Cited by
Structure, function and pathophysiology of protease activated receptors
MN Adams, R Ramachandran, MK Yau, JY Suen, DP Fairlie, ...
Pharmacology & therapeutics 130 (3), 248-282, 2011
Biased signalling and proteinase‐activated receptors (PARs): targeting inflammatory disease
MD Hollenberg, K Mihara, D Polley, JY Suen, A Han, DP Fairlie, ...
British journal of pharmacology 171 (5), 1180-1194, 2014
Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism
J Lim, A Iyer, L Liu, JY Suen, RJ Lohman, V Seow, MK Yau, L Brown, ...
The FASEB Journal 27 (12), 4757-4767, 2013
C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling
J Lim, A Iyer, JY Suen, V Seow, RC Reid, L Brown, DP Fairlie
The FASEB Journal 27 (2), 822-831, 2013
An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats
RJ Lohman, AJ Cotterell, GD Barry, L Liu, JY Suen, DA Vesey, DP Fairlie
The FASEB Journal 26 (7), 2877-2887, 2012
Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110)
JY Suen, GD Barry, RJ Lohman, MA Halili, AJ Cotterell, GT Le, DP Fairlie
British journal of pharmacology 165 (5), 1413-1423, 2012
Novel agonists and antagonists for human protease activated receptor 2
GD Barry, JY Suen, GT Le, A Cotterell, RC Reid, DP Fairlie
Journal of medicinal chemistry 53 (20), 7428-7440, 2010
Antagonism of protease-activated receptor 2 protects against experimental colitis
RJ Lohman, AJ Cotterell, J Suen, L Liu, AT Do, DA Vesey, DP Fairlie
Journal of Pharmacology and Experimental Therapeutics 340 (2), 256-265, 2012
Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a
V Seow, J Lim, A Iyer, JY Suen, JK Ariffin, DM Hohenhaus, MJ Sweet, ...
The Journal of Immunology 191 (8), 4308-4316, 2013
Profiling gene expression induced by protease-activated receptor 2 (PAR2) activation in human kidney cells
JY Suen, B Gardiner, S Grimmond, DP Fairlie
PLoS One 5 (11), e13809, 2010
An inhibitor of phospholipase A2 group IIA modulates adipocyte signaling and protects against diet-induced metabolic syndrome in rats
A Iyer, J Lim, H Poudyal, RC Reid, JY Suen, J Webster, JB Prins, ...
Diabetes 61 (9), 2320-2329, 2012
Pathway‐selective antagonism of proteinase activated receptor 2
JY Suen, A Cotterell, RJ Lohman, J Lim, A Han, MK Yau, L Liu, ...
British journal of pharmacology 171 (17), 4112-4124, 2014
Short hydrophobic peptides with cyclic constraints are potent glucagon-like peptide-1 receptor (GLP-1R) agonists
HN Hoang, K Song, TA Hill, DR Derksen, DJ Edmonds, WM Kok, ...
Journal of medicinal chemistry 58 (9), 4080-4085, 2015
Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists
V Seow, J Lim, AJ Cotterell, MK Yau, W Xu, RJ Lohman, WM Kok, ...
Scientific reports 6 (1), 1-12, 2016
Downsizing a human inflammatory protein to a small molecule with equal potency and functionality
RC Reid, MK Yau, R Singh, JK Hamidon, AN Reed, P Chu, JY Suen, ...
Nature communications 4 (1), 1-9, 2013
PAR2-induced inflammatory responses in human kidney tubular epithelial cells
DA Vesey, JY Suen, V Seow, RJ Lohman, L Liu, GC Gobe, DW Johnson, ...
American Journal of Physiology-Renal Physiology 304 (6), F737-F750, 2013
Biased Signaling by Agonists of Protease Activated Receptor 2
Y Jiang, MK Yau, WM Kok, J Lim, KC Wu, L Liu, TA Hill, JY Suen, ...
ACS Chemical Biology 12 (5), 1217-1226, 2017
Acquired von Willebrand syndrome in respiratory extracorporeal life support: a systematic review of the literature.
M Malfertheiner, L Pimenta, V von Bahr, J Millar, N Obonyo, J Suen, ...
Crit Care Resusc 19 ((Suppl 1)), 45-52, 2017
A refined agonist pharmacophore for protease activated receptor 2
GD Barry, JY Suen, HB Low, B Pfeiffer, B Flanagan, M Halili, GT Le, ...
Bioorganic & medicinal chemistry letters 17 (20), 5552-5557, 2007
A potent antagonist of protease-activated receptor 2 that inhibits multiple signaling functions in human cancer cells
Y Jiang, MK Yau, J Lim, KC Wu, W Xu, JY Suen, DP Fairlie
Journal of Pharmacology and Experimental Therapeutics 364 (2), 246-257, 2018
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