| Sildenafil reverses ABCB1-and ABCG2-mediated chemotherapeutic drug resistance Z Shi, AK Tiwari, S Shukla, RW Robey, S Singh, IW Kim, SE Bates, ... Cancer research 71 (8), 3029-3041, 2011 | 181 | 2011 |
| Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft models AK Tiwari, K Sodani, C Dai, AH Abuznait, S Singh, ZJ Xiao, A Patel, ... Cancer letters 328 (2), 307-317, 2013 | 126 | 2013 |
| Multiple transport-active binding sites are available for a single substrate on human P-glycoprotein (ABCB1) EE Chufan, K Kapoor, HM Sim, S Singh, TT Talele, SR Durell, ... PloS one 8 (12), e82463, 2013 | 120 | 2013 |
| Neratinib reverses ATP-binding cassette B1-mediated chemotherapeutic drug resistance in vitro, in vivo, and ex vivo X Zhao, J Xie, X Chen, HM Sim, X Zhang, Y Liang, S Singh, TT Talele, ... Molecular pharmacology 82 (1), 47-58, 2012 | 94 | 2012 |
| The phosphodiesterase-5 inhibitor vardenafil is a potent inhibitor of ABCB1/P-glycoprotein transporter PR Ding, AK Tiwari, S Ohnuma, JWKK Lee, X An, CL Dai, QS Lu, S Singh, ... PloS one 6 (4), e19329, 2011 | 92 | 2011 |
| Structure-based virtual screening, synthesis and SAR of novel inhibitors of hepatitis C virus NS5B polymerase TT Talele, P Arora, SS Kulkarni, MR Patel, S Singh, M Chudayeu, ... Bioorganic & medicinal chemistry 18 (13), 4630-4638, 2010 | 92 | 2010 |
| Design and synthesis of human ABCB1 (P-glycoprotein) inhibitors by peptide coupling of diverse chemical scaffolds on carboxyl and amino termini of (S)-valine-derived thiazole … S Singh, NR Prasad, EE Chufan, BA Patel, YJ Wang, ZS Chen, ... Journal of Medicinal Chemistry 57 (10), 4058-4072, 2014 | 62 | 2014 |
| GW583340 and GW2974, human EGFR and HER-2 inhibitors, reverse ABCG2-and ABCB1-mediated drug resistance K Sodani, AK Tiwari, S Singh, A Patel, ZJ Xiao, JJ Chen, YL Sun, ... Biochemical pharmacology 83 (12), 1613-1622, 2012 | 61 | 2012 |
| Telatinib reverses chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivo K Sodani, A Patel, N Anreddy, S Singh, DH Yang, RJ Kathawala, P Kumar, ... Biochemical pharmacology 89 (1), 52-61, 2014 | 58 | 2014 |
| PD173074, a selective FGFR inhibitor, reverses ABCB1-mediated drug resistance in cancer cells. ZSC Atish Patel, Amit K. Tiwari, Eduardo E. Chufan Cancer Chemotherapy and Pharmacology, 2013 | 58 | 2013 |
| Blockade of Her2/neu Binding to Hsp90 by Emodin Azide Methyl Anthraquinone Derivative Induces Proteasomal Degradation of Her2/neu Y Yan, L Zheng, X Zhang, L Chen, S Singh, F Wang, J Zhang, Y Liang, ... Molecular pharmaceutics 8 (5), 1687-1697, 2011 | 57 | 2011 |
| The synthesis of phenylalanine-derived C5-substituted rhodanines and their activity against selected methicillin-resistant Staphylococcus aureus (MRSA) strains D Hardej, CR Ashby Jr, NS Khadtare, SS Kulkarni, S Singh, TT Talele European journal of medicinal chemistry 45 (12), 5827-5832, 2010 | 57 | 2010 |
| Saracatinib (AZD0530) is a potent modulator of ABCB1‐mediated multidrug resistance in vitro and in vivo KJ Liu, JH He, XD Su, HM Sim, JD Xie, XG Chen, F Wang, YJ Liang, ... International journal of cancer 132 (1), 224-235, 2013 | 56 | 2013 |
| Synthesis and SAR optimization of quinazolin-4 (3H)-ones as poly (ADP-ribose) polymerase-1 inhibitors SS Kulkarni, S Singh, JR Shah, WK Low, TT Talele European journal of medicinal chemistry 50, 264-273, 2012 | 49 | 2012 |
| Centrosomal kinase Nek2 cooperates with oncogenic pathways to promote metastasis TK Das, D Dana, SS Paroly, SK Perumal, S Singh, H Jhun, J Pendse, ... Oncogenesis 2 (9), e69-e69, 2013 | 46 | 2013 |
| Enhancing chemosensitivity in ABCB1-and ABCG2-overexpressing cells and cancer stem-like cells by an Aurora kinase inhibitor CCT129202 C Cheng, Z Liu, H Zhang, J Xie, X Chen, X Zhao, F Wang, Y Liang, ... Molecular Pharmaceutics 9 (7), 1971-1982, 2012 | 41 | 2012 |
| QSAR studies on benzoylaminobenzoic acid derivatives as inhibitors of β-ketoacyl-acyl carrier protein synthase III S Singh, LK Soni, MK Gupta, YS Prabhakar, SG Kaskhedikar European journal of medicinal chemistry 43 (5), 1071-1080, 2008 | 35 | 2008 |
| BIRB796, the Inhibitor of p38 Mitogen-Activated Protein Kinase, Enhances the Efficacy of Chemotherapeutic Agents in ABCB1 Overexpression Cells D He, X Zhao, X Chen, Y Fang, S Singh, TT Talele, H Qiu, Y Liang, ... PLOS ONE 8 (1), e54181, 2013 | 30 | 2013 |
| Zafirlukast antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance YL Sun, RJ Kathawala, S Singh, K Zheng, TT Talele, WQ Jiang, ZS Chen Anti-cancer drugs 23 (8), 865-873, 2012 | 28 | 2012 |
| Design, Synthesis, and Biological Evaluation of (S)‐Valine Thiazole‐Derived Cyclic and Noncyclic Peptidomimetic Oligomers as Modulators of Human P … S Singh, NR Prasad, K Kapoor, EE Chufan, BA Patel, SV Ambudkar, ... ChemBioChem 15 (1), 157-169, 2014 | 21 | 2014 |
Zhe-Sheng ChenCollege of Pharmacy and Health Sciences, St. John's UniversityVerified email at stjohns.edu
